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المؤلفون: Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Sheena Pinto, Jens Pahl, Susanne Wingert, Joachim Koch, Björn Önfelt
المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
مصطلحات موضوعية: Pharmacology, Antibody-dependent cell-mediated cytotoxicity, Cancer Research, CD30, biology, Chemistry, medicine.drug_class, Immunology, Cell, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Monoclonal antibody, Immunological synapse, medicine.anatomical_structure, Cell killing, Oncology, medicine, Cancer research, biology.protein, Molecular Medicine, Immunology and Allergy, Cytotoxic T cell, Antibody, RC254-282
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b100f0a38751dbd8cb307946ee8d85Test
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adfTest -
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المؤلفون: Armin Beez, Sheena Pinto, Joachim Koch, Uwe Reusch, Jens Pahl, Arndt Schottelius, Susanne Wingert, Sabrina Purr
المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
مصطلحات موضوعية: Pharmacology, Cancer Research, Chemistry, Phagocytosis, Immunology, Cell, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Tumor cells, Cell biology, medicine.anatomical_structure, Oncology, medicine, Molecular Medicine, Immunology and Allergy, Macrophage, RC254-282
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753cab66c676cb1fc5a7c8dfa46be9d2Test
https://doi.org/10.1136/jitc-2021-sitc2021.880Test -
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المؤلفون: Sheena Pinto, Bruno Kyewski, Benedikt Brors, Corey N. Miller, Chloé Michel, Rita Küchler, Mark S. Anderson
المصدر: The Journal of Immunology. 199:3488-3503
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Cellular differentiation, Immunology, Cell, Apoptosis, Thymus Gland, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Agglutinin, Pregnancy, Lectins, medicine, Animals, Humans, Immunology and Allergy, Cell Lineage, Cells, Cultured, Mice, Knockout, Regulation of gene expression, MHC class II, biology, Histocompatibility Antigens Class II, FOXN1, Cell Differentiation, Epithelial Cells, Rats, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, biology.protein, Female, Biomarkers, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fefd1ab5ec945e00696024102c279fTest
https://doi.org/10.4049/jimmunol.1700203Test -
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المؤلفون: Gabriele Hintzen, Erich Rajkovic, Uwe Reusch, Jens Pahl, Arndt Schottelius, Torsten Haneke, Christian Breunig, Wolfgang Fischer, Andreas Harstrick, Sheena Pinto, Joachim Koch, Cassandra Choe-Juliak
المصدر: Cancer Research. 81:1881-1881
مصطلحات موضوعية: Antibody-dependent cell-mediated cytotoxicity, Cancer Research, Innate immune system, medicine.drug_class, business.industry, Cell, Cancer, Monoclonal antibody, medicine.disease, medicine.disease_cause, Immune system, medicine.anatomical_structure, Oncology, medicine, Cancer research, KRAS, business, EGFR inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::648b22f37267ea46b5922c3d8fa34cdbTest
https://doi.org/10.1158/1538-7445.am2021-1881Test -
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المؤلفون: Christoph Steeneck, Olaf Kinzel, Simon Anderhub, Aurélie Mallinger, Marta Czekańska, Sheena Pinto, Barbara Morschhaeuser, Christina Sonnek, Martin Hornberger, Thomas J. Hoffmann, Michael Albers, Yansong Wang
المصدر: Bioorganic & Medicinal Chemistry Letters. 33:127738
مصطلحات موضوعية: Lipopolysaccharides, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, Bridged Bicyclo Compounds, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Pharmacokinetics, Drug Discovery, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Enzyme Inhibitors, Molecular Biology, Heme, Kynurenine, ADME, Whole blood, Oxamic Acid, Dose-Response Relationship, Drug, Molecular Structure, Bicyclic molecule, 010405 organic chemistry, Organic Chemistry, Amides, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, chemistry, Hepatocyte, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373dcfd00c06df0df2fd5d34994a7c3eTest
https://doi.org/10.1016/j.bmcl.2020.127738Test -
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المؤلفون: Matthias Kuhn, Karen Cerosaletti, Anna Lissina, Georgia Afonso, Raphael Scharfmann, Jean-Paul Beressi, Etienne Larger, Francesco Dotta, Bruno Kyewski, Laura Nigi, Howard W. Davidson, Guido Sebastiani, David Price, Manuela Battaglia, Roberto Mallone, Søren Buus, Klaudia Kuranda, Sheena Pinto, Slobodan Culina, Ezio Bonifacio, James E. McLaren, Victor Appay, Ana Inés Lalanne, Thomas Osterbye, Kristin Ladell, Sophie Caillat-Zucman, Anne Eugster, Alicia Maugein
المساهمون: Mallone, Roberto, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Sorbonne Paris Cité (USPC), Université Paris Descartes - Paris 5 (UPD5), Translational Research Program [Seattle, WA, USA], Benaroya Research Institute [Seattle, WA, USA], Division of Developmental Immunology [Heidelberg, Germany], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Department of Medicine, Surgery and Neuroscience [Siena, Italy] (Diabetes Unit), University Hospital of Siena [Italy]-Fondazione Umberto di Mario ONLUS [Siena, Italy]-Toscana Life Sciences [Siena, Italy], CRTD-DFG Research Center for Regenerative Therapies Dresden [Dresden, Germany] (Medical Faculty), Technische Universität Dresden = Dresden University of Technology (TU Dresden), Department of Immunology and Microbiology [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Division of Infection and Immunity [Cardiff, UK] (School of Medicine), Cardiff University, Service de diabétologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Diabétologie [CH Versailles André Mignot, Le Chesnay], Centre Hospitalier de Versailles André Mignot (CHV), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Departement Hospitalo- Universitaire - Fight Ageing and STress [Paris] (DHU - FAST), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Barbara Davis Center for Childhood Diabetes (BDC), University of Colorado Anschutz [Aurora], Vaccine Research Center [Bethesda, MD, USA], National Institutes of Health [Bethesda] (NIH), Institut für Medizinische Informatik und Biometrie [Dresden, Germany] (Medical Faculty), Diabetes Research Institute [Milan, Italy], IRCCS Ospedale San Raffaele [Milan, Italy], Immunologie, génétique et traitement des maladies métaboliques et du diabète (UMR_S 561), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Jean Dausset d'Immunologie et d'Histocompatibilité [AP-HP Hôpital Saint-Louis], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], This work was performed within the Département Hospitalo-Universitaire AutHorS, supported by the Programme Hospitalier de Recherche Clinique ImMaDiab, Lilly France, the INSERM-Transfert Proof-of-Concept program acDC, the Ile-de-France CORDDIM, and grants from the JDRF (1-PNF-2014-155-A-V and 2-SRA-2016-164- Q-R), the Aviesan/Astra Zeneca 'Diabetes and the Vessel Wall Injury' program, the Société Francophone du Diabète, the Agence Nationale de la Recherche (ANR-2015-CE17-0018-01), the Fondation pour la Recherche Médicale (Equipe FRM DEQ20140329520), and the Helmsley Charitable Trust George S. Eisenbarth nPOD Award for Team Science (2015PG-T1D052) (to R.M.), a JDRF Biomarkers grant (17-2012-598) (to K.C.), an NIH R01 grant (DK052068) (to H.W.D.), Lilly and Fondation Bettencourt-Schueller funds (to R.S.), a European Research Council grant (ERC-2012-AdG) (to B.K.), and funds from JDRF, the Wellcome Trust, and the National Institute for Health Research Cambridge Biomedical Research Centre [to the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory (Cambridge Institute for Medical Research, University of Cambridge), which provided PBMC samples from the JDRF D-GAP study]. Samples from at-risk patients were obtained through a TrialNet ancillary study to the TN-01 Pathway to Prevention study funded by NIH grants U01 DK061010, U01 DK061034, U01 DK061042, U01 DK061058, U01 DK085465, U01 DK085453, U01 DK085461, U01 DK085463, U01 DK085466, U01 DK085499, U01 DK085504, U01 DK085505, U01 DK085509, U01 DK103180, U01- DK103153, U01-DK085476, and U01-DK103266 and by JDRF. D.A.P. is a Wellcome Trust Senior Investigator (100326Z/12/Z). This research was performed with the support of the nPOD, a collaborative T1D research project funded by JDRF. Organ procurement organizations partnering with nPOD to provide research resources are listed at www.jdrfnpod.org/ for-partners/npod-partners/. This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (INNODIA, no. 115797). This Joint Undertaking receives support from the Union’s Horizon 2020 research and innovation program and the European Federation of Pharmaceutical Industries and Associations, JDRF, and the Leona M. and Harry B. Helmsley Charitable Trust., Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Institutes of Health [Bethesda] (NIH)-National Institutes of Health, Bethesda
المصدر: Science Immunology
Science Immunology, 2018, 3 (20), ⟨10.1126/sciimmunol.aao4013⟩
Science Immunology, American Association for the Advancement of Science, 2018, 3 (20), ⟨10.1126/sciimmunol.aao4013⟩مصطلحات موضوعية: 0301 basic medicine, geography, endocrine system, geography.geographical_feature_category, endocrine system diseases, [SDV.IMM] Life Sciences [q-bio]/Immunology, T cell, Immunology, General Medicine, Biology, Islet, Epitope, 3. Good health, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Antigen, Cell culture, Interferon, medicine, Cytotoxic T cell, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD8, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a7fec2e9c93b9cae858cfe4689cdaTest
https://www.hal.inserm.fr/inserm-01918833/documentTest -
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المؤلفون: Bruno Kyewski, Sheena Pinto, Iris Martin, Chloé Michel, Rita Küchler
المصدر: Journal of immunological methods. 457
مصطلحات موضوعية: 0301 basic medicine, Immunology, Population, Cell Count, Thymus Gland, 03 medical and health sciences, Mice, In vivo, medicine, Immunology and Allergy, Animals, education, Lymph node, Cell Proliferation, education.field_of_study, DNA synthesis, Staining and Labeling, Chemistry, Cell growth, Cell Differentiation, Epithelial Cells, Flow Cytometry, Deoxyuridine, Small intestine, Epithelium, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Administration, Intravenous, Ex vivo
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634e4971f547692a8c9a8b9769d7dceeTest
https://pubmed.ncbi.nlm.nih.gov/29605230Test -
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المؤلفون: Sheena Pinto, Gisela Eisenhardt, Thomas J. Hoffmann, Larisa Buselic-Wölfel, Christoph Steeneck, Ulrich Deuschle, Claus Kremoser, Manfred Birkel, Michael Albers, Simon Anderhub
المصدر: Cancer Research. 79:1210-1210
مصطلحات موضوعية: Cancer Research, biology, Chemistry, T cell, medicine.medical_treatment, respiratory system, Aryl hydrocarbon receptor, Interleukin 22, Immune system, medicine.anatomical_structure, Oncology, Cancer immunotherapy, Cancer cell, Cancer research, biology.protein, medicine, Cytotoxic T cell, CD8
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::49b671b22ab8f90e48cb999731a57b9fTest
https://doi.org/10.1158/1538-7445.am2019-1210Test -
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المؤلفون: Evis Havari, HuiJuan Lv, Roderick T. Bronson, Kai W. Wucherpfennig, Bruno Kyewski, Myra A. Lipes, Shannon J. Turley, Raju V. S. R. K. Gottumukkala, Anne L. Fletcher, Ross O. Smith, Sheena Pinto, Khadir Raddassi, Anthony Rosenzweig, Lizbeth Cornivelli, Takashi Matsui
المصدر: Journal of Clinical Investigation. 121:1561-1573
مصطلحات موضوعية: Stromal cell, Myocarditis, HLA-DQ Antigen, T cell, macromolecular substances, General Medicine, Biology, musculoskeletal system, medicine.disease_cause, medicine.disease, Autoimmunity, Immune tolerance, medicine.anatomical_structure, Immunology, Myosin, medicine, MYH6, tissues
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::20199e382883a91197bd1bc761dfed2aTest
https://doi.org/10.1172/jci44583Test -
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المؤلفون: Stefanie Rösch, Bruno Kyewski, Klaus Hexel, Sheena Pinto, Jens Derbinski
المصدر: Proceedings of the National Academy of Sciences. 105:657-662
مصطلحات موضوعية: T cell, Locus (genetics), Thymus Gland, Autoimmune Diseases, Mice, Gene expression, medicine, Animals, Lactation, Gene, Mice, Knockout, Regulation of gene expression, Mice, Inbred C3H, Stochastic Processes, Multidisciplinary, biology, Caseins, Epithelial Cells, Biological Sciences, Milk Proteins, Autoimmune regulator, Molecular biology, medicine.anatomical_structure, Gene Expression Regulation, B7-1 Antigen, Lactalbumin, biology.protein, Female, Whey Acidic Protein, Central tolerance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4054052ee86818f40e8a10740f41a8aaTest
https://doi.org/10.1073/pnas.0707486105Test