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المؤلفون: Derek H. Oakley, Caitlin Commins, Matthew P. Frosch, Simon Dujardin, Mirra Chung, Bradley T. Hyman, Rachel E. Bennett, Naomi Klickstein
المصدر: The Journal of Neuroscience
مصطلحات موضوعية: Male, 0301 basic medicine, Programmed cell death, Cell Survival, Induced Pluripotent Stem Cells, PSEN1 L435F, tau Proteins, medicine.disease_cause, Mice, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Neurobiology of Disease, neurotoxicity, mental disorders, MAPT, Presenilin-1, medicine, PSEN1, Animals, Humans, Induced pluripotent stem cell, Research Articles, Cells, Cultured, Aged, 80 and over, Mutation, iPSC, tau aggregation, Chemistry, General Neuroscience, Neurotoxicity, Alzheimer's disease, tau seeding, Middle Aged, medicine.disease, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Tauopathies, nervous system, Cell culture, Female, Neurotoxicity Syndromes, Neuron, FTLD, 030217 neurology & neurosurgery, Intracellular
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb21addd0ffb109091b3e2bb911d6459Test
https://doi.org/10.1523/jneurosci.2590-20.2021Test -
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المؤلفون: Caitlin Commins, Bradley T. Hyman, Naomi Klickstein, Matthew P. Frosch, Simon Dujardin, Tarun V. Kamath, Analiese R. Fernandes, Derek H. Oakley
المصدر: Brain Communications
مصطلحات موضوعية: 0301 basic medicine, Future studies, Growth phase, Tau protein, Kinetics, 03 medical and health sciences, 0302 clinical medicine, propagation, medicine, Bioassay, tau, biology, Chemistry, AcademicSubjects/SCI01870, General Engineering, Human brain, Patient specific, medicine.disease, Editor's Choice, 030104 developmental biology, medicine.anatomical_structure, kinetics, biology.protein, Biophysics, Original Article, AcademicSubjects/MED00310, Alzheimer's disease, heterogeneity, 030217 neurology & neurosurgery, seeding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4578b1f2f301413149cb507766d9d9cTest
https://pubmed.ncbi.nlm.nih.gov/34222869Test -
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المؤلفون: Judith A. Steen, Dinorah Jean-Gilles, Pieter Beerepoot, Naomi Klickstein, Bradley T. Hyman, Mark B. De Los Santos, Tarun V. Kamath, Renee Moore, Arthur Viode, Aurélien Lathuilière, Lori B. Chibnik, Matthew P. Frosch, Ryan C. Clark, Derek H. Oakley, Alberto Serrano-Pozo, Benjamin D. Moore, Fiona Elwood, Rudolph E. Tanzi, Diana L. Corjuc, Simon Dujardin, Analiese R. Fernandes, Matthew E. Kennedy, Patrick M. Dooley, Bianca T. Corjuc, Kristina Mullin, Caitlin Commins, Kevin Atchison
المصدر: Nat Med
Nature medicine, Vol. 26, No 8 (2020) pp. 1256-1263مصطلحات موضوعية: 0301 basic medicine, Male, Cerebral Cortex / metabolism, Neurofibrillary Tangles / pathology, Disease, Protein aggregation, Severity of Illness Index, 0302 clinical medicine, Neurofibrillary Tangles / metabolism, Cognitive Dysfunction / pathology, Age of Onset, Phosphorylation, Aged, 80 and over, Cerebral Cortex, Tau Proteins / genetics, Cognition, Neurofibrillary Tangles, General Medicine, Middle Aged, Phenotype, 3. Good health, Alzheimer Disease / genetics, medicine.anatomical_structure, Cerebral Cortex / pathology, Cerebral cortex, 030220 oncology & carcinogenesis, Female, tau Proteins, Biology, Protein Aggregation, Pathological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Genetic Heterogeneity, Alzheimer Disease, Protein Aggregation, Pathological / genetics, medicine, Humans, Cognitive Dysfunction, Aged, Protein Aggregation, Pathological / pathology, Genetic heterogeneity, Neurofibrillary Tangles / genetics, Alzheimer Disease / pathology, Cancer, medicine.disease, Alzheimer Disease / metabolism, 030104 developmental biology, Cognitive Dysfunction / genetics, Age of onset, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7bb689b9606b3271da239615caaeaaTest
https://pubmed.ncbi.nlm.nih.gov/33514949Test -
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المؤلفون: Bradley T. Hyman, Naomi Klickstein, Marc Aurel Busche, George A. Carlson, Tarun V. Kamath, Julia Schiantarelli, Israel Nelken, Susanne Wegmann, Simon Dujardin, Caitlin Commins
المصدر: Nature reviews / Neuroscience 22(1), 57-64 (2018). doi:10.1038/s41593-018-0289-8
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, genetics [Plaque, Amyloid], pathology [Nerve Net], genetics [Alzheimer Disease], Plaque, Amyloid, tau Proteins, Article, 03 medical and health sciences, pathology [Alzheimer Disease], Mice, 0302 clinical medicine, In vivo, pathology [Brain], Alzheimer Disease, ddc:570, Gene expression, mental disorders, Biological neural network, medicine, Gene silencing, pathology [Neurons], Animals, Cognitive decline, metabolism [Nerve Net], Neurons, Neocortex, Chemistry, General Neuroscience, Brain, Neurofibrillary Tangles, Entorhinal cortex, metabolism [Plaque, Amyloid], metabolism [tau Proteins], genetics [tau Proteins], Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, metabolism [Neurofibrillary Tangles], metabolism [Brain], metabolism [Neurons], pathology [Neurofibrillary Tangles], Nerve Net, Neuroscience, 030217 neurology & neurosurgery, metabolism [Alzheimer Disease]
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29983d3e8c01d73ef951fcb7d2301504Test
https://pubmed.ncbi.nlm.nih.gov/30559471Test