المؤلفون: Nicola Pavese, Jacopo Pasquini, David J. Brooks

المصدر: Mov Disord Clin Pract
Pasquini, J, Brooks, D J & Pavese, N 2021, ' The Cholinergic Brain in Parkinson's Disease ', Movement Disorders Clinical Practice, vol. 8, no. 7, pp. 1012-1026 . https://doi.org/10.1002/mdc3.13319Test

مصطلحات موضوعية: Parkinson's disease, BASAL FOREBRAIN, Reviews, Hippocampus, Amygdala, BASAL FOREBRAIN ATROPHY, cholinergic, VISUAL HALLUCINATIONS, falls, medicine, Cognitive decline, OLFACTORY DYSFUNCTION, Mesopontine, Denervation, Basal forebrain, business.industry, ACETYLTRANSFERASE ACTIVITY, medicine.disease, ALZHEIMERS-DISEASE, SUBSTANTIA INNOMINATA, medicine.anatomical_structure, SLEEP BEHAVIOR DISORDER, Neurology, LATENCY AFFERENT INHIBITION, Cholinergic, PEDUNCULOPONTINE NUCLEUS, NUCLEUS BASALIS, Neurology (clinical), business, Neuroscience, dementia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6209dace9244f31b3a7821d391277cTest
https://doi.org/10.1002/mdc3.13319Test

المؤلفون: Gaia Rizzo, Paul M. Matthews, Jan Passchier, Robert A. Comley, Anne Lingford-Hughes, Hideo Tsukada, Courtney A. Bishop, Ashwin V. Venkataraman, Laigao Chen, Richard Hargreaves, David J. Brooks, Ayla Mansur, Laurent Martarello, James B. Rowe, Roger N. Gunn, Eugenii A. Rabiner, Adam J. Schwarz, Yvonne Lewis, Mickael Huiban, Ece Kocagoncu

مصطلحات موضوعية: Nuclear magnetic resonance, medicine.anatomical_structure, Neurite, Chemistry, Fractional anisotropy, medicine, Parietal lobe, Hippocampus, Alzheimer's disease, Grey matter, medicine.disease, Temporal lobe, Diffusion MRI

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::36a1470caa30c0c57536da263a5026c2Test
https://doi.org/10.1101/2021.11.23.21266746Test

المؤلفون: Anne M. Landau, Majken B. Thomsen, Heidi Kaastrup Müller, Jan Jacobsen, Dariusz Orlowski, Aage Kristian Olsen Alstrup, Thea P. Lillethorup, Simone L. Baerentzen, Ove Noer, Betina Elfving, Anna C. Schacht, David J. Brooks

المصدر: Thomsen, M B, Schacht, A C, Alstrup, A K O, Jacobsen, J, Lillethorup, T P, Bærentzen, S L, Noer, O, Orlowski, D, Elfving, B, Müller, H K, Brooks, D J & Landau, A M 2020, ' Preclinical PET Studies of [ 11 C]UCB-J Binding in Minipig Brain ', Molecular Imaging and Biology, vol. 22, no. 5, pp. 1290-1300 . https://doi.org/10.1007/s11307-020-01506-8Test

مصطلحات موضوعية: Cancer Research, education.field_of_study, medicine.diagnostic_test, Chemistry, Population, Synaptic vesicle, 030218 nuclear medicine & medical imaging, White matter, Synapse, 03 medical and health sciences, fluids and secretions, 0302 clinical medicine, medicine.anatomical_structure, Oncology, In vivo, Positron emission tomography, embryonic structures, Centrum semiovale, medicine, Biophysics, Radiology, Nuclear Medicine and imaging, education, SV2A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692ef3bc0973db1969e21b8c07830caTest
https://doi.org/10.1007/s11307-020-01506-8Test

المؤلفون: Per Borghammer, Karen Østergaard, Peter Parbo, Arne Møller, Kristian Stær, David J. Brooks, Nicola Pavese, Alicia Garrido, Eduardo Tolosa, Morten Gersel Stokholm, Mónica Serradell, María José Martí, Alex Iranzo

المصدر: Stokholm, M G, Garrido, A, Tolosa, E, Serradell, M, Iranzo, A, Ostergaard, K, Borghammer, P, Moller, A, Parbo, P, Staer, K, Brooks, D J, Jose Marti, M & Pavese, N 2020, ' Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers ', Journal of Neurology, vol. 267, no. 8, pp. 2296-2300 . https://doi.org/10.1007/s00415-020-09830-3Test
Journal of Neurology

مصطلحات موضوعية: 0301 basic medicine, PENETRANCE, medicine.medical_specialty, Parkinson's disease, Neurology, Dopamine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Asymptomatic, DISEASE, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, medicine, Humans, Movement disorders, Neuroinflammation, Subclinical infection, Original Communication, Microglia, business.industry, Parkinsonism, SYNUCLEINOPATHIES, Parkinson Disease, medicine.disease, nervous system diseases, PATHOLOGY, PET, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Clinical neurology, Mutation, Parkinson’s disease, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d9ae05a56f269dd603e6775f67cce3Test
https://doi.org/10.1007/s00415-020-09830-3Test

المؤلفون: Joan Santamaria, Tatyana D. Fedorova, Kotaro Hiraoka, Alicia Garrido, Marit Otto, Nobuyuki Okamura, Anette Torvin Møller, Alex Iranzo, Carles Gaig, Dolores Vilas, M. Gersel Stokholm, Eduard Tolosa, Karen Østergaard, David J. Brooks, Nicola Pavese, Per Borghammer, Mónica Serradell, K. Bacher Svendsen

المصدر: Gersel Stokholm, M, Iranzo, A, Østergaard, K, Serradell, M, Otto, M, Bacher Svendsen, K, Garrido, A, Vilas, D, Fedorova, T D, Santamaria, J, Møller, A, Gaig, C, Hiraoka, K, Brooks, D J, Okamura, N, Borghammer, P, Tolosa, E & Pavese, N 2020, ' Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder ', European Journal of Neurology, vol. 27, no. 4, pp. 644-652 . https://doi.org/10.1111/ene.14127Test

مصطلحات موضوعية: DOPAMINERGIC DEFICITS, Male, Cingulate cortex, positron emission tomography, Parkinson's disease, Polysomnography, REM Sleep Behavior Disorder, Lewy body disease, DIAGNOSIS, 03 medical and health sciences, 0302 clinical medicine, PARKINSONS-DISEASE, mental disorders, MANAGEMENT, medicine, Cholinesterases, Humans, Dementia, 030212 general & internal medicine, rapid eye movement sleep behaviour disorder, Aged, Temporal cortex, Dementia with Lewy bodies, business.industry, DEMENTIA, Parkinsonism, NEURODEGENERATION, Brain, Montreal Cognitive Assessment, ACETYLTRANSFERASE ACTIVITY, Middle Aged, COGNITIVE IMPAIRMENT, medicine.disease, LEWY BODIES, Denervation, acetylcholine, Dihydroxyphenylalanine, ALZHEIMERS-DISEASE, Dorsolateral prefrontal cortex, medicine.anatomical_structure, Neurology, Positron-Emission Tomography, Female, Neurology (clinical), business, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6bb785d695e7d8b6bc98668eed9bcbTest
http://hdl.handle.net/10097/00130915Test

المؤلفون: Eugenii A. Rabiner, G. Pagano, K. Ray Chaudhuri, Nicola Pavese, S. Molloy, David J. Brooks, Peter G. Bain

المصدر: Pagano, G, Molloy, S, Bain, P G, Rabiner, E A, Ray Chaudhuri, K, Brooks, D J & Pavese, N 2021, ' Impulse control disorders are associated with lower ventral striatum dopamine D3 receptor availability in Parkinson's disease : A [ 11 C]-PHNO PET study ', Parkinsonism and Related Disorders, vol. 90, pp. 52-56 . https://doi.org/10.1016Test/j.parkreldis.2021.06.025
Pagano, G, Molloy, S, Bain, P G, Rabiner, E A, Ray Chaudhuri, K, Brooks, D J & Pavese, N 2021, ' Impulse control disorders are associated with lower ventral striatum dopamine D3 receptor availability in Parkinson's disease : A [11C]-PHNO PET study ', Parkinsonism & Related Disorders, vol. 90, pp. 52-56 . https://doi.org/10.1016Test/j.parkreldis.2021.06.025

مصطلحات موضوعية: medicine.medical_specialty, Parkinson's disease, Impulse control disorder, business.industry, Dopaminergic, Ventral striatum, Impulse control disorders, medicine.disease, medicine.anatomical_structure, Endocrinology, Neurology, nervous system, PHNO PET, Dopamine receptor, Dopamine receptor D3, Dopamine, Internal medicine, Radioligand, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Dopaminergic receptor type 3, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ff649aed11a34e9bce84ebf953dd9eTest
https://pure.au.dk/portal/da/publications/impulse-control-disorders-are-associated-with-lower-ventral-striatum-dopamine-d3-receptor-availability-in-parkinsons-diseaseTest(c4f22c42-b744-435f-99c0-a48155600d39).html

المؤلفون: Karen Østergaard, Carles Gaig, David J. Brooks, Kristine Farmen, Eduardo Tolosa, Mónica Serradell, Per Borghammer, Kristina Bacher Svendsen, Alicia Garrido, Morten Gersel Stokholm, Marit Otto, Alex Iranzo, Sara K. Nissen, Arne Møller, Nicola Pavese, Joan Santamaria, Dolores Vilas, Marina Romero-Ramos

المصدر: Farmen, K, Nissen, S K, Stokholm, M G, Iranzo, A, Østergaard, K, Serradell, M, Otto, M, Svendsen, K B, Garrido, A, Vilas, D, Borghammer, P, Santamaria, J, Møller, A, Gaig, C, Brooks, D J, Tolosa, E, Pavese, N & Romero-Ramos, M 2021, ' Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 10, e2020858118 . https://doi.org/10.1073/pnas.2020858118Test
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, Positron emission tomography, ALPHA-SYNUCLEIN, Inflammation, Substantia nigra, REM Sleep Behavior Disorder, REM sleep behavior disorder, Monocytes, Immune system, Neuroinflammation, PARKINSONS-DISEASE, medicine, Humans, TLR4, Aged, Neurons, Synucleinopathies, CD11b Antigen, Multidisciplinary, business.industry, Parkinsonism, Monocyte, HLA-DR Antigens, Biological Sciences, Middle Aged, medicine.disease, Substantia Nigra, Toll-Like Receptor 4, medicine.anatomical_structure, Positron-Emission Tomography, CELLS, Immunology, Female, CD163, medicine.symptom, monocytes, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2becded01064f4f976e0f987f5c183a5Test
https://doi.org/10.1073/pnas.2020858118Test

المؤلفون: Stefan Carver, Naghma Malik, Craig W. Ritchie, Sanara Raza, John E Harrison, Salman Karim, Gregor Russell, David J. Brooks, Clive Holmes, George Tadros, Gail Busza, Vandana Mate, Sajeev Kshemendran, Anthony Peter Passmore, Basil H. Ridha, Thalia van der Doef, Lucy Knight, Kehinde Junaid, Elizabeth Coulthard, Ben Underwood, Hilary Archer, Tricia Tan, Sharon Love, Zuzana Walker, Paul Koranteng, Ajayverma Macharouthu, Bernadette McGuinness, Andrew Donaldson, Simon Thacker, Clive Ballard, Grazia Daniela Femminella, Paul Edison, Valeria Calsolaro, Aparna Prasanna, Ramin Nilforooshan, Nicholas R Livingston, Christian Hölscher, Robert M. Lawrence, Carol Bannister, Brady McFarlane, Eleni Frangou

المساهمون: Femminella, G. D., Livingston, N. R., Raza, S., van der Doef, T., Frangou, E., Love, S., Busza, G., Calsolaro, V., Carver, S., Holmes, C., Ritchie, C. W., Lawrence, R. M., Mcfarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B., Prasanna, A., Koranteng, P., Karim, S., Junaid, K., Mcguinness, B., Passmore, A. P., Nilforooshan, R., Macharouthu, A., Donaldson, A., Thacker, S., Russell, G., Malik, N., Mate, V., Knight, L., Kshemendran, S., Tan, T., Holscher, C., Harrison, J., Brooks, D. J., Ballard, C., Edison, P.

المصدر: Femminella, G D, Livingston, N R, Raza, S, van der Doef, T, Frangou, E, Love, S, Busza, G, Calsolaro, V, Carver, S, Holmes, C, Ritchie, C W, Lawrence, R M, McFarlane, B, Tadros, G, Ridha, B H, Bannister, C, Walker, Z, Archer, H, Coulthard, E, Underwood, B, Prasanna, A, Koranteng, P, Karim, S, Junaid, K, McGuinness, B, Passmore, A P, Nilforooshan, R, Macharouthu, A, Donaldson, A, Thacker, S, Russell, G, Malik, N, Mate, V, Knight, L, Kshemendran, S, Tan, T, Holscher, C, Harrison, J, Brooks, D J, Ballard, C & Edison, P 2021, ' Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? ', Alzheimer's Research and Therapy, vol. 13, 47 (2021) . https://doi.org/10.1186/s13195-021-00784-wTest
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2021)
Femminella, G D, Livingston, N R, Raza, S, Van Der Doef, T, Frangou, E, Love, S, Busza, G, Calsolaro, V, Carver, S, Holmes, C, Ritchie, C W, Lawrence, R M, Mcfarlane, B, Tadros, G, Ridha, B H, Bannister, C, Walker, Z, Archer, H, Coulthard, E, Underwood, B, Prasanna, A, Koranteng, P, Karim, S, Junaid, K, Mcguinness, B, Passmore, A P, Nilforooshan, R, Macharouthu, A, Donaldson, A, Thacker, S, Russell, G, Malik, N, Mate, V, Knight, L, Kshemendran, S, Tan, T, Holscher, C, Harrison, J, Brooks, D J, Ballard, C & Edison, P 2021, ' Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects? ', Alzheimer's research & therapy, vol. 13, no. 1 . https://doi.org/10.1186/s13195-021-00784-wTest
Femminella, G D, Livingston, N R, Raza, S, van der Doef, T, Frangou, E, Love, S, Busza, G, Calsolaro, V, Carver, S, Holmes, C, Ritchie, C W, Lawrence, R M, McFarlane, B, Tadros, G, Ridha, B H, Bannister, C, Walker, Z, Archer, H, Coulthard, E, Underwood, B, Prasanna, A, Koranteng, P, Karim, S, Junaid, K, McGuinness, B, Passmore, A P, Nilforooshan, R, Macharouthu, A, Donaldson, A, Thacker, S, Russell, G, Malik, N, Mate, V, Knight, L, Kshemendran, S, Tan, T, Holscher, C, Harrison, J, Brooks, D J, Ballard, C & Edison, P 2021, ' Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? ', Alzheimer's Research & Therapy, vol. 13, no. 1, pp. 47 . https://doi.org/10.1186/s13195-021-00784-wTest
Femminella, G D, Livingston, N R, Raza, S, van der Doef, T, Frangou, E, Love, S, Busza, G, Calsolaro, V, Carver, S, Holmes, C, Ritchie, C W, Lawrence, R M, McFarlane, B, Tadros, G, Ridha, B H, Bannister, C, Walker, Z, Archer, H, Coulthard, E, Underwood, B, Prasanna, A, Koranteng, P, Karim, S, Junaid, K, McGuinness, B, Passmore, A P, Nilforooshan, R, Macharouthu, A, Donaldson, A, Thacker, S, Russell, G, Malik, N, Mate, V, Knight, L, Kshemendran, S, Tan, T, Holscher, C, Harrison, J, Brooks, D J, Ballard, C & Edison, P 2021, ' Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? ', Alzheimer's research & therapy, vol. 13, 47 . https://doi.org/10.1186/s13195-021-00784-wTest

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Type 2 diabetes, lcsh:RC346-429, 0302 clinical medicine, 11 Medical and Health Sciences, education.field_of_study, Brain, Alzheimer's disease, Magnetic Resonance Imaging, medicine.anatomical_structure, Neurology, Homeostatic model assessment, Life Sciences & Biomedicine, Alzheimer’s disease, Human, medicine.medical_specialty, Cognitive Neuroscience, Population, Clinical Neurology, Carbohydrate metabolism, Grey matter, lcsh:RC321-571, 03 medical and health sciences, Insulin resistance, Magnetic resonance imaging, SDG 3 - Good Health and Well-being, Alzheimer Disease, Fluorodeoxyglucose F18, Internal medicine, medicine, Humans, Positron emission tomography imaging, education, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, lcsh:Neurology. Diseases of the nervous system, Science & Technology, business.industry, Insulin, Research, Neurosciences, medicine.disease, Hyperintensity, 030104 developmental biology, Endocrinology, Glucose, Diabetes Mellitus, Type 2, Positron-Emission Tomography, Neurology (clinical), Neurosciences & Neurology, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abff61b5a79367e8f0ad4dae69e46610Test
https://research-information.bris.ac.uk/ws/files/277990943/s13195_021_00784_w.pdfTest

المؤلفون: David J. Brooks, Richard Nicholas, Sujata Sridharan, Paolo A. Muraro, David R. Owen, Roger N. Gunn, Chris Record, Ashwini Nandoskar, David J. Sharp, Joel Raffel

المساهمون: Medical Research Council (MRC), Imperial College Healthcare NHS Trust- BRC Funding, Alzheimer's Research UK (ARUK), National Institute for Health Research

المصدر: Sridharan, S, Raffel, J, Nandoskar, A, Record, C, Brooks, D, Owen, D, Sharp, D, Muraro, P, Gunn, R & Nicholas, R 2019, ' Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [ 18 F]GE-180 : a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter ', Multiple Sclerosis Journal, vol. 21, no. 5, pp. 935-944 . https://doi.org/10.1007/s11307-019-01323-8Test

مصطلحات موضوعية: Cancer Research, Grey matter, Occupancy plot, 030218 nuclear medicine & medical imaging, Multiple sclerosis, 03 medical and health sciences, 0302 clinical medicine, In vivo, Translocator protein, medicine, Radioligand, [ C]PBR28, Radiology, Nuclear Medicine and imaging, [ F]GE-180, Receptor, [11C]PBR28, Volume of distribution, [18F]GE-180, biology, medicine.diagnostic_test, Chemistry, 1103 Clinical Sciences, 0606 Physiology, medicine.disease, Molecular biology, Polymorphism plot, Nuclear Medicine & Medical Imaging, PET, medicine.anatomical_structure, Oncology, Positron emission tomography, biology.protein, XBD173

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1357100ca4d9a95a191965559dd24a8Test
https://doi.org/10.1007/s11307-019-01323-8Test

المؤلفون: Allan K Hansen, Martin B. Kinnerup, Katrine B. Andersen, Per Borghammer, Michael Sommerauer, Nathalie Van Den Berge, Adjmal Nahimi, Tatyana D. Fedorova, Kim Vang, Nicola Pavese, David J. Brooks, Karoline Knudsen

المصدر: Andersen, K B, Hansen, A K, Sommerauer, M, Fedorova, T D, Knudsen, K, Vang, K, Van Den Berge, N, Kinnerup, M, Nahimi, A, Pavese, N, Brooks, D J & Borghammer, P 2020, ' Altered sensorimotor cortex noradrenergic function in idiopathic REM sleep behaviour disorder-A PET study ', Parkinsonism & Related Disorders, vol. 75, pp. 63-69 . https://doi.org/10.1016Test/j.parkreldis.2020.05.013
Andersen, K B, Hansen, A K, Sommerauer, M, Fedorova, T D, Knudsen, K, Vang, K, Van Den Berge, N, Kinnerup, M, Nahimi, A, Pavese, N, Brooks, D J & Borghammer, P 2020, ' Altered sensorimotor cortex noradrenergic function in idiopathic REM sleep behaviour disorder : A PET study ', Parkinsonism & Related Disorders, vol. 75, pp. 63-69 . https://doi.org/10.1016Test/j.parkreldis.2020.05.013

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Parkinson's disease, Morpholines, Idiopathic rapid-eye-movement (REM) sleep behaviour disorder (RBD), REM Sleep Behavior Disorder, Primary motor-sensory cortex, Statistical parametric mapping, Norepinephrine, 03 medical and health sciences, 0302 clinical medicine, Thalamus, Internal medicine, Humans, Medicine, Aged, C-MeNER positron emission tomography (PET), Denervation, biology, business.industry, Putamen, Binding potential, Parkinson Disease, Middle Aged, Ligand (biochemistry), medicine.disease, Dihydroxyphenylalanine, Cortex (botany), 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Neurology, Norepinephrine transporter, Positron-Emission Tomography, Noradrenaline, biology.protein, Motor cortex, Female, Sensorimotor Cortex, Neurology (clinical), Geriatrics and Gerontology, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57f9c52285071388567f1d52f24f364Test
https://pure.au.dk/portal/da/publications/altered-sensorimotor-cortex-noradrenergic-function-in-idiopathic-rem-sleep-behaviour-disorder--a-pet-studyTest(91764d3c-2a82-47e2-b9f5-a6781bf47d10).html