المؤلفون: Christian U. Blank, Paulien Cornelissen-Steijger, Aida Shahrabi, Oscar Krijgsman, Petra Ross-Macdonald, Daniel S. Peeper, John B. A. G. Haanen, Martin Del Castillo Velasco-Herrera, Kristel Kemper, Maarten A. Ligtenberg, Sofia Ibanez Molero, David W. Vredevoogd, Julia Boshuizen, Roelof J.C. Kluin, Ji-Ying Song, Thomas Kuilman, Elisa A. Rozeman, Beaunelle de Bruijn, David J. Adams

المصدر: Clinical Cancer Research. 27:5389-5400

مصطلحات موضوعية: Cancer Research, business.industry, Melanoma, Programmed Cell Death 1 Receptor, Cell, RNA, medicine.disease, Immune checkpoint, Blockade, Transplantation, Mice, medicine.anatomical_structure, Oncology, CTLA-4, Tumor Microenvironment, Cancer research, Animals, Humans, Medicine, Cytotoxic T cell, CTLA-4 Antigen, business, Immune Checkpoint Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f4efae16e2251e152c52de002875ffTest
https://doi.org/10.1158/1078-0432.ccr-20-4218Test

المؤلفون: Simone Brokamp, Annegien Broeks, Christian U. Blank, Petra Herzig, Marlous van den Braber, Daniela S. Thommen, Alfred Zippelius, Marjolein de Bruijn, Joyce Sanders, Ton N. Schumacher, Lisanne M. Roelofsen, Koen J. Hartemink, John B. A. G. Haanen, Kim Monkhorst, Paula Voabil, Sanne H. Hendriks

المصدر: Nature Medicine. 27:1250-1261

مصطلحات موضوعية: business.industry, medicine.medical_treatment, Cell, Cancer, General Medicine, Immunotherapy, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Blockade, medicine.anatomical_structure, Immune system, Cell culture, medicine, Cancer research, Pd 1 blockade, business, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c45c19b51a9c099f12311a77da46c458Test
https://doi.org/10.1038/s41591-021-01398-3Test

المؤلفون: Sanne Patiwael, Christian U. Blank, Ton N. Schumacher, Antoni Ribas, John B. A. G. Haanen, Anastasia Gangaev, Daisy Philips, Dirk Schadendorf, Joost H. van den Berg, Maartje W. Rohaan, Bastian Schilling, Elisa A. Rozeman, Pia Kvistborg, Olga I. Isaeva

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 43

مصطلحات موضوعية: Male, Receptors, Antigen, T-Cell, alpha-beta, Programmed Cell Death 1 Receptor, Medizin, Epitopes, T-Lymphocyte, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Epitope, Cohort Studies, Epitopes, melanoma-reactive CD8 T cells, Receptors, PD-1, 80 and over, Cytotoxic T cell, CTLA-4 Antigen, Hepatitis A Virus Cellular Receptor 2, Immune Checkpoint Inhibitors, Melanoma, Cancer, alpha-beta, Aged, 80 and over, Multidisciplinary, Middle Aged, Biological Sciences, medicine.anatomical_structure, 5.1 Pharmaceuticals, Antigen, Female, Development of treatments and therapeutic interventions, medicine.symptom, Melanoma-Specific Antigens, Adult, Receptors, CXCR5, T cell, In Vitro Techniques, Clinical Research, medicine, Humans, Aged, business.industry, Compartment (ship), T-Cell, medicine.disease, CXCR5, Blockade, Kinetics, T-Lymphocyte, Mechanism of action, CTLA-4, Cancer research, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994323e563648a11d8ffa0127b701604Test
https://doi.org/10.1073/pnas.2102849118Test

المؤلفون: B.A. van de Wiel, Charlotte L. Zuur, Serigne Lo, Michel W.J.M. Wouters, Carolien Bierman, María Jesús González González, Elena Shklovskaya, Christian U. Blank, Willem M.C. Klop, Elisa A. Rozeman, Robert V. Rawson, J.B.A.G. Haanen, Omgo E. Nieweg, James S. Wilmott, Andrew J. Spillane, Robyn P. M. Saw, J.V. van Thienen, C. Adhikari, Sydney Ch'ng, A.C.J. van Akkooi, Michael T. Tetzlaff, Hanna Eriksson, Helen Rizos, Alexander Guminski, Richard A. Scolyer, Kerwin F. Shannon, W.J. van Houdt, Jonathan R. Stretch, Georgina V. Long, A.M. Menzies

المصدر: Annals of Oncology, 32(6), 766-777. ELSEVIER

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Skin Neoplasms, medicine.medical_treatment, Ipilimumab, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, Internal medicine, medicine, Humans, Melanoma, Pathological, Lymph node, business.industry, neoadjuvant, Reproducibility of Results, Hematology, Immunotherapy, medicine.disease, Neoadjuvant Therapy, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Biomarker (medicine), immunotherapy, Nivolumab, business, pathological response, medicine.drug, metastatic melanoma

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb61a837c13200f2514a9ed7c1f22afTest
https://hdl.handle.net/1887/3276136Test

المؤلفون: Christian U. Blank, B. Schermers, Sara H. Muller, A.C.J. van Akkooi, Annemarie Bruining, B.A. van de Wiel, Viola Franke, Carolien Bierman, W.J. van Houdt, Theo J.M. Ruers, B. ten Haken, Elisa A. Rozeman, Michel W.J.M. Wouters

المساهمون: Nanobiophysics, Magnetic Detection and Imaging, Technical Medicine

المصدر: The British Journal of Surgery
British journal of surgery, 106(5), 519-522. Wiley

مصطلحات موضوعية: Oncology, Male, medicine.medical_specialty, medicine.medical_treatment, UT-Hybrid-D, Pilot Projects, 030230 surgery, 03 medical and health sciences, Magnetics, 0302 clinical medicine, Antineoplastic Agents, Immunological, Internal medicine, Surgical removal, Medicine, Humans, Stage III melanoma, In patient, General, Rapid Research Communication, Lymph node, Melanoma, Neoadjuvant therapy, Neoplasm Staging, Ultrasonography, business.industry, Node (networking), Immunotherapy, Middle Aged, Ipilimumab, Neoadjuvant Therapy, Dissection, medicine.anatomical_structure, Nivolumab, Lymphatic Metastasis, Lymph Node Excision, Surgery, Female, Lymph Nodes, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e573d5fff633f1dd2bc58d6eb5e9d35Test
http://www.scopus.com/inward/record.url?scp=85063523883&partnerID=8YFLogxKTest

المؤلفون: Giampaolo Tortora, Bernard A. Fox, Ramy Ibrahim, Christian U. Blank, Alexander M.M. Eggermont, Michael Lahn, Anna Maria Di Giacomo, Michele Maio, R. Bryan Bell, Andrea Necchi

المساهمون: Maio, M., Blank, C., Necchi, A., Di Giacomo, A. M., Ibrahim, R., Lahn, M., Fox, B. A., Bell, R. B., Tortora, G., Eggermont, A. M. M.

مصطلحات موضوعية: 0301 basic medicine, Oncology, PD-L1, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Neoadjuvant trials, Biomarkers, Bladder cancer, CTLA-4, Head and neck cancer, Immunotherapy, Melanoma, Pancreatic cancer, PD-1, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Internal medicine, Tumor Microenvironment, medicine, Humans, CTLA-4 Antigen, Immune Checkpoint Inhibitors, Lymph node, business.industry, Cancer, medicine.disease, Head and neck squamous-cell carcinoma, Neoadjuvant Therapy, 030104 developmental biology, medicine.anatomical_structure, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Adenocarcinoma, Neoplasm Recurrence, Local, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba278732050d946d514842ba857bccaTest
https://hdl.handle.net/11365/1233299Test

المؤلفون: Ton N. Schumacher, Elisa A. Rozeman, Bastian Schilling, Maartje W. Rohaan, John B. A. G. Haanen, Pia Kvistborg, Antoni Ribas, Dirk Schadendorf, Sanne Patiwael, Joost H. van den Berg, Anastasia Gangaev, Daisy Philips, Christian U. Blank

مصطلحات موضوعية: business.industry, Melanoma, T cell, medicine.disease, Epitope, Peripheral, Blockade, medicine.anatomical_structure, Mechanism of action, CTLA-4, Cancer research, Medicine, Cytotoxic T cell, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::55f4778522d652e945a423a387342f2dTest
https://doi.org/10.1101/2020.12.15.422827Test

المؤلفون: Christian U. Blank, Elisa A. Rozeman, David W. Vredevoogd, Hugo M. Horlings, Stephanie A. Blankenstein, Marieke Brüggemann, Julia Boshuizen, Beaunelle de Bruijn, Juliana C.N. Kenski, Max F. Madu, Keith T. Flaherty, Alexander C.J. van Akkooi, Ji-Ying Song, Dennie T. Frederick, Mara Parren, Oscar Krijgsman, Daniel S. Peeper, Maarten A. Ligtenberg, Genevieve M. Boland

المساهمون: Plastic, Reconstructive and Hand Surgery

المصدر: Nature communications, 11(1):3946. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, Skin Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, General Physics and Astronomy, Cancer immunotherapy, 02 engineering and technology, Mice, Antineoplastic Agents, Immunological, Tumor Microenvironment, Cytotoxic T cell, RNA-Seq, lcsh:Science, Melanoma, education.field_of_study, Multidisciplinary, 021001 nanoscience & nanotechnology, Gene Expression Regulation, Neoplastic, Cancer therapeutic resistance, medicine.anatomical_structure, Female, 0210 nano-technology, Proto-Oncogene Proteins B-raf, Science, Tumour heterogeneity, T cell, Population, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immune system, Antigen, Cell Line, Tumor, medicine, Animals, Humans, education, neoplasms, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, business.industry, Brain-Derived Neurotrophic Factor, General Chemistry, Immunotherapy, medicine.disease, Xenograft Model Antitumor Assays, HEK293 Cells, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, lcsh:Q, Tumor Escape, business, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169ac84a0fc19e200b0badf8c6a353cfTest
https://pure.amc.nl/en/publications/reversal-of-preexisting-ngfrdriven-tumor-and-immune-therapy-resistanceTest(dda4d8a2-a72f-4a5a-b05a-12bc7aa97702).html

المؤلفون: Christian U. Blank, Astrid A M van der Veldt, Alfonsus J M van den Eertwegh, Ellen Kapiteijn, Anne M. May, Djura Piersma, Rik J Verheijden, Geke A. P. Hospers, Michel W.J.M. Wouters, Maureen J.B. Aarts, Marye Boers-Sonderen, Karijn P M Suijkerbuijk, Albert J. ten Tije, Franchette W P J van den Berkmortel, Jacobus J.M. van der Hoeven, Rozemarijn S. van Rijn, Jan Willem B. de Groot, Michiel C T van Zeijl, John B. A. G. Haanen, Gerard Vreugdenhil

المساهمون: CCA - Cancer Treatment and quality of life, CCA - Cancer biology and immunology, AII - Cancer immunology, Medical oncology, Radiology & Nuclear Medicine, Medical Oncology, Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: ESMO OPEN, 5(6):000945. BMJ Publishing Group
Esmo Open, 5, 6
Esmo Open, 5
ESMO Open, 5(6):e000945. BMJ Publishing Group
ESMO Open, Vol 5, Iss 6 (2020)
ESMO Open, 5(6):000945. BMJ Publishing Group
ESMO Open, 5(6):000945. BMJ PUBLISHING GROUP
Verheijden, R J, May, A M, Blank, C U, van der Veldt, A A M, Boers-Sonderen, M J, Aarts, M J B, van den Berkmortel, F W P J, van den Eertwegh, A J M, de Groot, J W B, van der Hoeven, J J M, Hospers, G A P, Piersma, D, van Rijn, R S, ten Tije, A J, Vreugdenhil, G, van Zeijl, M C T, Wouters, M W J M, Haanen, J B A G, Kapiteijn, E & Suijkerbuijk, K P M 2020, ' Lower risk of severe checkpoint inhibitor toxicity in more advanced disease ', ESMO OPEN, vol. 5, no. 6, 000945 . https://doi.org/10.1136/esmoopen-2020-000945Test
ESMO Open, 5(6). BMJ PUBLISHING GROUP
ESMO Open

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, MONOTHERAPY, Disease, Lower risk, lcsh:RC254-282, Gastroenterology, Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18], Antineoplastic Agents, Immunological, Internal medicine, checkpoint inhibition, medicine, melanoma, Humans, immune-related adverse event (irAE), Prospective Studies, Stage (cooking), IMMUNOTHERAPY, anti-PD1, Adverse effect, Lymph node, Original Research, Retrospective Studies, DMTR, Performance status, IMMUNE CHECKPOINTS, business.industry, Melanoma, IPILIMUMAB, NIVOLUMAB, ASSOCIATION, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, CANCER, medicine.anatomical_structure, Oncology, Relative risk, SURVIVAL, Female, ADVERSE EVENTS, business, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b2810a24d327b462bf0cdb07832e35Test
https://research.vumc.nl/en/publications/7b0f1470-b2db-489e-b295-a031e5347867Test

المؤلفون: Adina Weinberger, Ron Shaoul, Morgan G. I. Langille, Alexandria P. Cogdill, Giuseppe Mallel, Talia Golan, Anat Ronai, Arnon Meltser, Vancheswaran Gopalakrishnan, Christian U. Blank, Jennifer A. Wargo, Einav Yehuda-Shnaidman, Tali Dadosh, Maya Dadiani, Daniel S. Peeper, Merav Rokah, Alon Ben-Nun, Reetakshi Arora, Elinor Gigi, Aviram Nissan, Keren Levanon, Zachary A. Cooper, Tatiana Dorfman, Gavin M. Douglas, Iris Kamer, Gabriel Ologun, Ilana Livyatan, Zvi R. Cohen, Iris Barshack, Noam Shental, Elisa A. Rozeman, Nicola Baldini, Einav Nili Gal-Yam, Nancy Gavert, Shlomit Yust-Katz, Ran Kremer, Eran Segal, Ravid Straussman, Roi Weiser, Yaara Zwang, Yuval Bussi, Hagit Shapira, Tehila Atlan, Dan J. Raz, Amnon Amit, Smadar Levin-Zaidman, Bella Kaufman, Aviva Rotter-Maskowitz, Keren Bahar-Shany, Tali Siegal, Abdul Wadud Khan, Judith Sandbank, Deborah Nejman, Gili Perry, Jair Bar, Maya Lotan-Pompan, Sofia Avnet, Ofra Golani, Garold Fuks, Leore T. Geller, Sagi Harnof

المساهمون: Nejman D., Livyatan I., Fuks G., Gavert N., Zwang Y., Geller L.T., Rotter-Maskowitz A., Weiser R., Mallel G., Gigi E., Meltser A., Douglas G.M., Kamer I., Gopalakrishnan V., Dadosh T., Levin-Zaidman S., Avnet S., Atlan T., Cooper Z.A., Arora R., Cogdill A.P., Khan M.A.W., Ologun G., Bussi Y., Weinberger A., Lotan-Pompan M., Golani O., Perry G., Rokah M., Bahar-Shany K., Rozeman E.A., Blank C.U., Ronai A., Shaoul R., Amit A., Dorfman T., Kremer R., Cohen Z.R., Harnof S., Siegal T., Yehuda-Shnaidman E., Gal-Yam E.N., Shapira H., Baldini N., Langille M.G.I., Ben-Nun A., Kaufman B., Nissan A., Golan T., Dadiani M., Levanon K., Bar J., Yust S., Barshack I., Peeper D.S., Raz D.J., Segal E., Wargo J.A., Sandbank J., Shental N., Straussman R.

المصدر: Science

مصطلحات موضوعية: 0301 basic medicine, Male, Colon, Macrophage, medicine.medical_treatment, Biology, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, RNA, Ribosomal, 16S, medicine, Microbiome, Breast, Lung, Multidisciplinary, Bacteria, Melanoma, Intracellular parasite, Microbiota, Ovary, Cancer, Immunotherapy, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Neoplasm, Female, Pancreas, Human

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c3a1966e5196491836aaf3aaf203f3Test
http://hdl.handle.net/11585/780581Test