المؤلفون: Minki Kim, Muhammad Irfan, Man Hee Rhee

المصدر: Journal of Ginseng Research, Vol 44, Iss 1, Pp 24-32 (2020)
Journal of Ginseng Research

مصطلحات موضوعية: 0301 basic medicine, MKK4, mitogen-activated protein kinase kinase 4, Ginsenosides, Syk, spleen tyrosine kinase, PPD, protopanaxadiol, AA, arachidonic acid, Review, vWF, von Willebrand factor, Pharmacology, ERK, extracellular signal–regulated kinase, chemistry.chemical_compound, Ginseng, 0302 clinical medicine, MLC, myosin light chain, lcsh:Botany, Medicine, PAR, proteinase-activated receptor, TS, total saponin, AC, adenylyl cyclase, media_common, GPVI, glycoprotein VI, [Ca2+]i, intracellular calcium ion, PI3K, phosphatidylinositol 3-kinase, lcsh:QK1-989, cAMP, cyclic adenosine monophosphate, IC50, half maximal (50%) inhibitory concentration, Ginsenoside, 030220 oncology & carcinogenesis, IP3, inositol-1,4,5-triphosphate, JNK, c-Jun N-terminal kinase, Nutraceutical, Biotechnology, Drug, Korean ginseng, ATP, adenosine triphosphate, media_common.quotation_subject, CRP, collagen-related peptide, aPTT, activated partial thromboplastin time, Biochemistry, Genetics and Molecular Biology (miscellaneous), World health, 03 medical and health sciences, PT, prothrombin time, PKC, protein kinase C, Antiplatelet, TxAS, thromboxane-A synthase, Platelet activation, ASA, acetylsalicylic acid, PAF, platelet-activating factor, TxB2, thromboxane B2, business.industry, cPLA2α, cytosolic phospholipase A2α, PLA2, phospholipase A2, Synergism, TxA2, thromboxane A2, PPT, protopanaxatriol, Anti platelet, ADP, adenosine diphosphate, COX, cyclooxygenase, 030104 developmental biology, CSF, crude saponin fraction, Complementary and alternative medicine, chemistry, ROCK, Rho-associated protein kinase, Structural modification, TxR, thromboxane receptor, Akt, protein kinase B, PLCγ2, phospholipase C gamma-2, PKG, protein kinase G, SFK, Src family kinase, PKA, protein kinase A, business, VASP, vasodilator-stimulated phosphoprotein, MAPK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77592e2f7358ae138f91eeb44c16a0d7Test
http://www.sciencedirect.com/science/article/pii/S1226845319301332Test

المؤلفون: Matthias Epple, Yana Dautova, Kevin Pappert, Alexander N. Kapustin, Martin D. Bootman, Hanneke Okkenhaug, Diane Proudfoot, Simon J. Cook, Catherine M. Shanahan

المصدر: Journal of Molecular and Cellular Cardiology
Dautova, Y, Kapustin, A, Pappert, K, Epple, M, Okkenhaug, H, Cook, S J, Shanahan, C M, Bootman, M D & Proudfoot, D 2017, ' Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells : A role for spleen tyrosine kinase and exosome release ', Journal of Molecular and Cellular Cardiology . https://doi.org/10.1016/j.yjmcc.2017.12.007Test

مصطلحات موضوعية: 0301 basic medicine, Calcium Phosphates, Male, BM, basal culture medium, Vascular smooth muscle, Inflammasomes, Interleukin-1beta, Syk, Exosomes, Muscle, Smooth, Vascular, SYK, Phosphorylation, Cells, Cultured, Caspase 1, Inflammasome, Middle Aged, CaP, calcium phosphate, Cell biology, VSMC, vascular smooth muscle cells, Caspase-1, Cytokines, LPS, lipopolysaccharide, Female, Cardiology and Cardiovascular Medicine, medicine.drug, Adult, IL-1β, interleukin-1β, ATP, adenosine triphosphate, Myocytes, Smooth Muscle, Chemie, chemistry.chemical_element, Calcium, Exosome, MSU, monosodium urate, Article, SYK, spleen tyrosine kinase, 03 medical and health sciences, Young Adult, medicine, SFM, serum-free medium, Humans, Syk Kinase, Secretion, NLRP3: nucleotide-binding domain, leucine-rich repeat/pyrin domain-containing-3, Molecular Biology, Calcium phosphate particles, Enzyme Activation, 030104 developmental biology, chemistry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d86e001074dcd1dcf16d9ed519a5db8Test
http://europepmc.org/articles/PMC5823844Test

المؤلفون: Edina Simon, Attila Mócsai, Dániel Csete, Zoltán Jakus, Petra Aradi, Dávid Győri, Szilvia Benkő, Ahmad Alatshan, Csaba Dobó-Nagy

المصدر: Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, lcsh:Immunologic diseases. Allergy, VAV1, mice, Immunology, Cre recombinase, Syk, Mice, Transgenic, chemical and pharmacologic phenomena, Biology, Bone resorption, Bone and Bones, Bone remodeling, 03 medical and health sciences, 0302 clinical medicine, Osteoclast, hemic and lymphatic diseases, medicine, Animals, Syk Kinase, Immunology and Allergy, Bone Resorption, Original Research, SYK (spleen tyrosine kinase), tyrosine kinase, hemic and immune systems, Organ Size, Hematopoietic Stem Cells, Cell biology, enzymes and coenzymes (carbohydrates), Haematopoiesis, in vivo, 030104 developmental biology, medicine.anatomical_structure, osteoclasts, Cre-Lox, biological phenomena, cell phenomena, and immunity, lcsh:RC581-607, Tyrosine kinase, Gene Deletion, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbcbb4bcf10f859bc6960f7c058a1b5Test

المؤلفون: Mingjiang Zhu, Mingming Zhao, Shanshan Zhong, Xinli Xue, Shuyuan Guo, L. L. Li, Jianhong Lu, Yongzhen Tao, Buxing Chen, Qun Chen, Mengqing Xiao, Yujuan Zhuo, Chunzhao Yin, Huiyong Yin, Lemin Zheng, Xia Shen

المصدر: Redox Biology, Vol 21, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: RT, retention time, Male, TLR4, Toll like receptor 4, BEP-CE, Bicyclic endoperoxide and hydroperoxide cholesterol ester, CHD, coronary heart disease, Biochemistry, Mass Spectrometry, Mice, 0302 clinical medicine, LXRα, liver X receptor α, oxLA-CE, oxidized LA-CE, Myocardial infarction, HMGCR, HMG-CoA reductase, CBD, cerebrovascular diseases, lcsh:QH301-705.5, chol-d7, cholesterol-d7, Idol, inducible degrader of the LDL receptor, AMVN, 2, 2′-azobis(2,4-dimethylvaleronitrile), GW, GW 3965, LDLR, LDL receptor, mmLDL, minimally modified LDL, Cholesterol, WT, wide type, Cardiovascular Diseases, Knockout mouse, MI, myocardial infarction, Cholesterol Esters, lcsh:Medicine (General), ch-HpETE, cholesteryl-hydroperoxy-eicosatetraenoate, medicine.medical_specialty, NH4OAc, ammonium acetate, LA-CEOH, LA-CE hydroxide, Lipid peroxidation, CVD, cardiovascular disease, SYK, spleen tyrosine kinase, 03 medical and health sciences, PUFA, polyunsaturated fatty acid, Humans, Aged, TLC, thin layer chromatography, Macrophages, ch-HpODE, cholesteryl-hydroperoxy-octadecadienoate, Lipid Metabolism, medicine.disease, Dil-LDL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl-indocarbocyanine perchlorate labeled LDL, 030104 developmental biology, Endocrinology, LA-CE, cholesteryl linoleate, LDL oxidation, Biomarkers, 030217 neurology & neurosurgery, MRM, multiple reaction monitoring, 0301 basic medicine, CE19:0, cholesteryl nonadecanoate, Clinical Biochemistry, ch-HODE, cholesteryl-hydroxy-octadecadienoate, Endogeny, LDL, low density lipoprotein, Pathogenesis, Cholesterol/metabolism, chemistry.chemical_compound, BSTFA+TMCS, Bis-(trimethylsilyl)-trifluoroacetamide+Trimethylchlorosilane, Cholesterol uptake, IS, internal standard, PPh3, triphenylphosphine, CEOH, CE hydroxide, Liver X Receptors, lcsh:R5-920, CEOOH, cholesterol ester hydroperoxide, Chemistry, BMDM, bone marrow-derived macrophage, Middle Aged, CVD, ch-13c,t-HpODE, cholesteryl-13(cis, trans)-hydroperoxy-octadecadienoate, ch-HETE, cholesteryl-hydroxy-eicosatetraenoate, Metabolome, LXR, Female, lipids (amino acids, peptides, and proteins), oxCE, oxidized CE, Research Paper, IPA, isopropanol, AA-CE, cholesteryl arachidonate, Cholesterol ester hydroperoxides, CE, cholesterol ester, T09, T0901317, ROS, reactive oxygen species, Internal medicine, BHT, butylated hydroxytoluene, medicine, Animals, oxLDL, oxidized LDL, Organic Chemistry, IP, intraperitoneal injection, Disease Models, Animal, LDLR, Receptors, LDL, lcsh:Biology (General), NaOMe, sodium methoxide, Lipidomics, LDL receptor, Hepatocytes, Chromatography, Liquid, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1989f770bc806092616979f001bbee92Test
http://www.sciencedirect.com/science/article/pii/S2213231718310851Test

المؤلفون: Palash Chandra Maity, Michael Reth, Kathrin Klaesener, Jianying Yang

المصدر: Biochimica et Biophysica Acta

مصطلحات موضوعية: Nanocluster, Syk, spleen tyrosine kinase, Cell, Receptors, Cell Surface, Biology, Article, PALM, photoactivated localization microscopy, Cell membrane, dSTORM, direct stochastic optical reconstruction microscopy, Cell Compartmentation, medicine, Animals, Humans, TEM, transmission electron microscopy, Molecular Biology, B cell antigen receptor, Protein islands, B-Lymphocytes, PLA, proximity ligation assay, BN-PAGE, blue native polyacrylamide gel electrophoresis, Cell Membrane, breakpoint cluster region, Models, Immunological, Biological membrane, Cell Biology, BCR, B cell antigen receptor, Cell biology, medicine.anatomical_structure, Membrane, Membrane protein, PM, plasma membrane, Nanoparticles, Fluid mosaic model, TM, transmembrane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436c2176277ef379c869f11a5ff32c87Test
http://europepmc.org/articles/PMC4547082Test

المؤلفون: Richard Leigh, David Proud

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: Rhinovirus, Syk, spleen tyrosine kinase, Respiratory Tract Diseases, RIP-1, receptor interacting protein-1, Epithelial cells, ICAM-1, intercellular adhesion molecule-1, Cystic fibrosis, Human rhinovirus, OAS, 2′5′-oligoadenylate synthetase, TRAF-3, TNF receptor-associated factor-3, Pathogenesis, CCL, chemokine (C-C motif) ligand, Pharmacology (medical), Respiratory system, mda-5, melanoma differentiation-associated gene-5, Innate immunity, COPD, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, Airway remodeling, CXCR, C-X-C chemokine receptor, VEGF, vascular endothelial growth factor, medicine.anatomical_structure, iNOS, inducible nitric oxide synthase, PAMP, pathogen-associated molecular pattern, TRIF, TIR-domain-containing adapter-inducing interferon-β, IPS-1, interferon-β promoter stimulating protein-1, COAST, Childhood Origins of Asthma, RT-PCR, reverse transcription-polymerase chain reaction, T helper 2, Th2, GM-CSF, granulocyte–macrophage colony-stimulating factor, HRV, human rhinovirus, ERK, extracellular-signal-regulated kinase, Antiviral Agents, Virus, Article, LABA, Long-acting β2-adrenergic agonist, medicine, Animals, Humans, ISG, interferon-stimulated gene, IFN, interferon, TLR, toll-like receptor, OCT, octamer transcription factor, Asthma, Respiratory Sounds, Pharmacology, CF, cystic fibrosis, CXCL, chemokine (C-X-C motif) ligand, FADD, fas-associated protein with death domain, MUC5AC, Mucin 5AC, NO, nitric oxide, Picornaviridae Infections, business.industry, MMP-9, matrix metalloproteinase-9, medicine.disease, G-CSF, granulocyte colony-stimulating factor, ICS, inhaled corticosteroids, Immunity, Innate, respiratory tract diseases, IL, interleukin, RIG-I, retinoic acid inducible gene-I, COPD, chronic obstructive pulmonary disease, PI-3 kinase, phosphatidylinositol-4,5-bisphosphate 3-kinase, PRR, pattern recognition receptors, Immunology, RNA, ribonucleic acid, dsRNA, double-stranded RNA, RSV, respiratory syncytial virus, business, Airway, Respiratory tract, IRF, interferon regulatory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceb543ec1943de9596fcd25ba010883Test
https://pubmed.ncbi.nlm.nih.gov/25550230Test

المؤلفون: Michelle Haber, Glenn M. Marshall, Jennifer A. Byrne, David S. Ziegler, Murray D. Norris, Federica Saletta, Geoffrey McCowage, Carol Wadham

المساهمون: Saletta, Federica, Wadham, Carol, Ziegler, David S, Marshall, Glenn M, Haber, Michelle, McCowage, G, Norris, Murray D, Byrne, Jennifer A

المصدر: BBA Clinical

مصطلحات موضوعية: CAR, chimeric antigen receptor, AURKB, aurora kinase B, PARP, poly(ADP-ribose) polymerase, medicine.medical_treatment, Hsp90, heat shock protein 90, Review, Bioinformatics, Ph +, Philadelphia chromosome-positive, Targeted therapy, SHH, sonic hedgehog, AURKA, aurora kinase A, IGF-1R, insulin-like growth factor type 1 receptor, HDAC, histone deacetylases, Medicine, Profiling (information science), PI3K, phosphatidylinositol 3′-kinase, BET, bromodomain and extra terminal, AML, acute myeloid leukemia, food and beverages, targeted therapy, 3. Good health, PLK1, polo-like kinase 1, AML - Acute myeloid leukemia, Molecular Medicine, RMS, rhabdomyosarcoma, ODC1, ornithine decarboxylase 1, DFMO, difluoromethylornithine, Childhood cancer, mAbs, monoclonal antibodies, mTOR, mammalian target of rapamycin, Pathology and Forensic Medicine, SYK, spleen tyrosine kinase, molecular diagnostics, CML, chronic myeloid leukemia, VEGF/VEGFR, vascular endothelial growth factor/receptor, IGF/IGFR, insulin-like growth factor/receptor, Physiology (medical), NSCLC, non-small cell lung cancer, Molecular diagnostics, childhood cancer, mAb, monoclonal antibody, TRAIL, TNF-related apoptosis-inducing ligand, business.industry, ALK, anaplastic lymphoma kinase, biomarkers, TOP1/TOP2, DNA topoisomerase 1/2, PDGFRA/B, platelet derived growth factor alpha/beta, CAR - Chimeric antigen receptor, ALL, acute lymphoblastic leukemia, EGFR, epidermal growth factor receptor, ERMS, embryonal rhabdomyosarcoma, DIPG, diffuse intrinsic pontine glioma, Non small lung cancer, ARMS, alveolar rhabdomyosarcoma, AT/RT, atypical teratoid/rhabdoid tumor, sense organs, business, ALL - Acute lymphoblastic leukemia, Biomarkers, SMO, smoothened

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d23899601b6c04d286e686871c94b25Test

المؤلفون: Marites P. Melancon, Jun Zhao, Min Zhou

المصدر: EBioMedicine
EBioMedicine, Vol 2, Iss 6, p 486 (2015)

مصطلحات موضوعية: Radiation-Sensitizing Agents, medicine.medical_treatment, Fusion Proteins, bcr-abl, lcsh:Medicine, Gene Expression, Syk, Apoptosis, Mice, SCID, medicine.disease_cause, Radiation Tolerance, Mice, Mice, Inbred NOD, BPL, B-precursor acute lymphoblastic leukemia, Cancer, lcsh:R5-920, education.field_of_study, Leukemia, Precision medicine, Intracellular Signaling Peptides and Proteins, General Medicine, Total body irradiation, Protein-Tyrosine Kinases, Combined Modality Therapy, Haematopoiesis, Treatment Outcome, Original Article, lcsh:Medicine (General), Whole-Body Irradiation, Bone marrow transplantation, Radiation resistance, Population, Mice, Transgenic, Disease-Free Survival, General Biochemistry, Genetics and Molecular Biology, SYK, spleen tyrosine kinase, Cell Line, Tumor, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, medicine, Animals, Humans, Syk Kinase, education, Protein Kinase Inhibitors, business.industry, lcsh:R, medicine.disease, Xenograft Model Antitumor Assays, Personalized medicine, LNP, liposomal nanoparticles, Mice, Inbred C57BL, Transplantation, Radiation therapy, Immunology, Liposomes, Commentary, Cancer research, Nanoparticles, business, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2148b1eab398c50110fdb4b1bb1ca272Test