نتائج البحث - "Horvitz, H. Robert"

المصدر: Omura, Daniel T., Damon A. Clark, Aravinthan D.T. Samuel, and H. Robert Horvitz. 2012. Dopamine signaling is essential for precise rates of locomotion by C. elegans. PLoS ONE 7(6): e38649.

العلاقة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374838/pdfTest/; PLoS ONE

الوصول الحر: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10403688Test

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النص الكامل

4

Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans

المؤلفون: H. Robert Horvitz, Holly Johnsen

المساهمون: Massachusetts Institute of Technology. Department of Biology, Horvitz, H. Robert, Johnsen, Holly L.

المصدر: BMC Biology
BioMed Central

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Engulfment, Physiology, Phagocytosis, Cell, Apoptosis, Plant Science, Phagoptosis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Structural Biology, medicine, Animals, RNA, Messenger, Assisted suicide, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Ecology, Evolution, Behavior and Systematics, Caspase, Agricultural and Biological Sciences(all), biology, Biochemistry, Genetics and Molecular Biology(all), Cell Biology, biology.organism_classification, 3. Good health, Cell biology, Repressor Proteins, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Caspases, C. elegans, biology.protein, General Agricultural and Biological Sciences, Plasmids, Research Article, Developmental Biology, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395d66ab728b244804a1769f95a8d855Test
https://doi.org/10.1186/s12915-016-0262-5Test

5

Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel to the Canonical Pathway for Apoptosis in Caenorhabditis elegans

المؤلفون: H. Robert Horvitz, Victoria Hatch, Daniel P. Denning

المساهمون: Massachusetts Institute of Technology. Department of Biology, Denning, Daniel Prudden, Hatch, Victoria, Horvitz, H. Robert

المصدر: PLoS
PLoS Genetics
PLoS Genetics, Vol 9, Iss 3, p e1003341 (2013)

مصطلحات موضوعية: Cancer Research, Programmed cell death, lcsh:QH426-470, Cell, Gene Identification and Analysis, Embryonic Development, Apoptosis, Cell Fate Determination, Molecular Genetics, 03 medical and health sciences, 0302 clinical medicine, parasitic diseases, Genetics, medicine, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Biology, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, Caspase, Tissue homeostasis, 030304 developmental biology, 0303 health sciences, biology, Calcium-Binding Proteins, Intrinsic apoptosis, fungi, Gene Expression Regulation, Developmental, biology.organism_classification, Embryonic stem cell, Molecular biology, 3. Good health, Cell biology, lcsh:Genetics, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Caspases, Mutation, biology.protein, Animal Genetics, 030217 neurology & neurosurgery, Research Article, Developmental Biology, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d2086428e76eb207daaff90ea338e8Test
https://orcid.org/0000-0002-9964-9613Test

6

The Caenorhabditis elegans Synthetic Multivulva Genes Prevent Ras Pathway Activation by Tightly Repressing Global Ectopic Expression of lin-3 EGF

المؤلفون: Adam M. Saffer, Dong hyun Kim, H. Robert Horvitz, Alexander van Oudenaarden

المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Horvitz, Howard Robert, Saffer, Adam M., Kim, Dong hyun, van Oudenaarden, Alexander, Horvitz, H. Robert

المصدر: PLoS Genetics
PLoS Genetics, Vol 7, Iss 12, p e1002418 (2011)
PLoS

مصطلحات موضوعية: Cancer Research, Organogenesis, Mutant, Gene Expression, medicine.disease_cause, Cell Fate Determination, 0302 clinical medicine, Gene expression, Pattern Formation, Promoter Regions, Genetic, Genetics (clinical), Caenorhabditis elegans, Genetics, 0303 health sciences, Mutation, biology, Gene targeting, Gene Expression Regulation, Developmental, Cell Differentiation, Animal Models, Phenotype, 3. Good health, Cell biology, Female, RNA Interference, Research Article, Signal Transduction, Transcriptional Activation, lcsh:QH426-470, MAP Kinase Signaling System, Vulva, Molecular Genetics, 03 medical and health sciences, Model Organisms, medicine, Animals, Gene Regulation, Caenorhabditis elegans Proteins, Molecular Biology, Gene, Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Epidermal Growth Factor, Molecular Development, biology.organism_classification, Signaling, Morphogens, lcsh:Genetics, Germ Cells, ras Proteins, Ectopic expression, Organism Development, Animal Genetics, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1542184b87f8f16815405af966e4c713Test
http://europepmc.org/articles/PMC3248470Test

7

Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans

المؤلفون: Aravinthan D. T. Samuel, H. Robert Horvitz, Damon A. Clark, Daniel T. Omura

المساهمون: Massachusetts Institute of Technology. Department of Biology, McGovern Institute for Brain Research at MIT, Horvitz, Howard Robert, Omura, Daniel T., Horvitz, H. Robert

المصدر: PLoS
PLoS ONE, Vol 7, Iss 6, p e38649 (2012)
PLoS ONE

مصطلحات موضوعية: Anatomy and Physiology, Heredity, Dopamine, Gene Identification and Analysis, lcsh:Medicine, Molecular neuroscience, GTP-Binding Protein alpha Subunits, Gi-Go, Biochemistry, Behavioral Neuroscience, 0302 clinical medicine, Neuromodulation, Neural Pathways, Molecular Cell Biology, Membrane Receptor Signaling, lcsh:Science, Caenorhabditis elegans, Genetics, 0303 health sciences, Multidisciplinary, Dopaminergic, Neurotransmitter Receptor Signaling, Neurochemistry, Animal Models, Neurotransmitters, 3. Good health, Cell biology, Phenotypes, medicine.anatomical_structure, Neurology, Dopamine receptor, Medicine, Neurochemicals, Signal transduction, Locomotion, Signal Transduction, Research Article, medicine.drug, Biology, Neurological System, Molecular Genetics, 03 medical and health sciences, Model Organisms, Genetic Mutation, Motor system, medicine, Animals, Gene Regulation, Caenorhabditis elegans Proteins, 030304 developmental biology, Motor Systems, Receptors, Dopamine D2, lcsh:R, biology.organism_classification, Mutagenesis, Mutation, Genetics of Disease, lcsh:Q, Molecular Neuroscience, 030217 neurology & neurosurgery, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b440556c2304e4b437c9a1b46bf4b8cTest
https://orcid.org/0000-0002-9964-9613Test

8

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

المساهمون: Massachusetts Institute of Technology. Department of Biology, Horvitz, H. Robert, University of Groningen

المصدر: Oxford Journals
Human molecular genetics, vol 18, iss 3
Human Molecular Genetics
Human Molecular Genetics, 18(3), 472-481. Oxford University Press

مصطلحات موضوعية: Male, Candidate gene, ELONGATOR, Morpholino, Genome-wide association study, SUSCEPTIBILITY, Medical and Health Sciences, AMYOTROPHIC-LATERAL-SCLEROSIS, DISEASE, Transgenic, Mice, MITOCHONDRIA, 80 and over, WIDE ASSOCIATION, Amyotrophic lateral sclerosis, Genetics (clinical), Zebrafish, Histone Acetyltransferases, Genetics, Aged, 80 and over, Motor Neurons, Genetics & Heredity, Neurodegeneration, General Medicine, Articles, Middle Aged, Biological Sciences, GENOME, POOLED DNA, Drosophila, Female, Adult, European Continental Ancestry Group, Mice, Transgenic, Nerve Tissue Proteins, and over, Biology, TARDBP, ELP3, White People, medicine, Animals, Humans, Genetic Predisposition to Disease, Molecular Biology, Gene, Aged, MUTATIONS, Amyotrophic Lateral Sclerosis, Genetic Variation, medicine.disease, POLYMORPHISM, Mutation

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0c2ce1af151c9cda2320ca0babfd8dTest
https://orcid.org/0000-0002-9964-9613Test

9

The Caenorhabditis elegans Iodotyrosine Deiodinase Ortholog SUP-18 Functions through a Conserved Channel SC-Box to Regulate the Muscle Two-Pore Domain Potassium Channel SUP-9

المؤلفون: Long Ma, Ignacio Perez de la Cruz, H. Robert Horvitz

المساهمون: Massachusetts Institute of Technology. Department of Biology, de la Cruz, Ignacio Perez, Horvitz, H. Robert

المصدر: PLoS Genetics
PLoS Genetics, Vol 10, Iss 2, p e1004175 (2014)
PLoS

مصطلحات موضوعية: Cancer Research, Potassium Channels, lcsh:QH426-470, Protein subunit, medicine.disease_cause, Iodide Peroxidase, 03 medical and health sciences, Model Organisms, 0302 clinical medicine, Genetics, medicine, Animals, Myocyte, Caenorhabditis elegans, Caenorhabditis elegans Proteins, music, Biology, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, Mutation, music.instrument, biology, Muscles, Membrane Proteins, biology.organism_classification, Potassium channel, Protein Structure, Tertiary, 3. Good health, lcsh:Genetics, Phenotype, Membrane protein, Biochemistry, Iodotyrosine deiodinase, medicine.symptom, 030217 neurology & neurosurgery, Research Article, Muscle contraction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df75ad9f786bb0db195ace3e9cc6a06Test
https://doi.org/10.1371/journal.pgen.1004175Test

10

A Neuronal Acetylcholine Receptor Regulates the Balance of Muscle Excitation and Inhibition in Caenorhabditis elegans

المؤلفون: Tamara M. Stawicki, Kim Schuske, Erik M. Jorgensen, Yishi Jin, H. Robert Horvitz, Jean-Louis Bessereau, Yingchuan Qi, Maelle Jospin, Thomas Boulin

المساهمون: Department of Biology [Utah], University of Utah, Physiologie intégrative, cellulaire et moléculaire (PICM), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Division of Biological Sciences [San Diego], University of California [San Diego] (UC San Diego), University of California-University of California, Biologie Cellulaire de la Synapse Normale et Pathologique, Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Biology, Howard Hughes Medical Institute (HHMI)-Massachusetts Institute of Technology (MIT), This work was supported initially by a Jane Coffin Childs postdoctoral fellowship to YJ. Further support was from National Institute of Health grants NS035546 to YJ, NS034307 to EJ, GM024663 to HRH, INSERM Junior Contract to TB, Association FranÃƒ§aise Contre les Myopathies and ANR-07-NEURO-032-01 grants to J-LB, and Human Frontier Science Program long term fellowship to MJ. YBQ is an associate of, and YJ, EJ, and HRH are investigators of the Howard Hughes Medical Institute., Massachusetts Institute of Technology. Department of Biology, McGovern Institute for Brain Research at MIT, Horvitz, H. Robert, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), School of Biological Sciences [Univ California San Diego] (UC San Diego), University of California (UC)-University of California (UC), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Autard, Delphine

المصدر: PLoS Biology
PLoS Biology, Public Library of Science, 2009, 7 (12), pp.e1000265. ⟨10.1371/journal.pbio.1000265⟩
PLoS Biology, Vol 7, Iss 12, p e1000265 (2009)
PLoS
PLoS Biology, 2009, 7 (12), pp.e1000265. ⟨10.1371/journal.pbio.1000265⟩

مصطلحات موضوعية: MESH: Muscle Contraction, Xenopus, MESH: Amino Acid Sequence, MESH: gamma-Aminobutyric Acid, Receptors, Nicotinic, Synaptic Transmission, 0302 clinical medicine, MESH: Xenopus, MESH: Animals, Biology (General), Receptor, gamma-Aminobutyric Acid, Motor Neurons, 0303 health sciences, Neuroscience/Behavioral Neuroscience, General Neuroscience, MESH: Caenorhabditis elegans Proteins, Cell biology, Genetics and Genomics/Gene Function, MESH: Receptors, Nicotinic, GABAergic, medicine.symptom, General Agricultural and Biological Sciences, MESH: Motor Neurons, Locomotion, Acetylcholine, Muscle Contraction, Research Article, medicine.drug, Muscle contraction, medicine.medical_specialty, MESH: Mutation, QH301-705.5, Molecular Sequence Data, MESH: Locomotion, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, macromolecular substances, Neurotransmission, Biology, General Biochemistry, Genetics and Molecular Biology, gamma-Aminobutyric acid, 03 medical and health sciences, MESH: Caenorhabditis elegans, Internal medicine, MESH: Synaptic Transmission, medicine, Animals, Amino Acid Sequence, Caenorhabditis elegans, Caenorhabditis elegans Proteins, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, 030304 developmental biology, Acetylcholine receptor, MESH: Molecular Sequence Data, General Immunology and Microbiology, MESH: Acetylcholine, Endocrinology, Mutation, Cholinergic, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d49a8148971c137fbb0f6732644645Test
https://doi.org/10.1371/journal.pbio.1000265Test

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