نتائج البحث - "Flaviano Giorgini"

المصدر: Drug Discovery Today
Collier, M E W, Zhang, S, Scrutton, N & Giorgini, F 2021, ' Inflammation control and improvement of cognitive function in COVID-19 infections: Is there a role for kynurenine 3-monooxygenase inhibition? ', Drug discovery today . https://doi.org/10.1016/j.drudis.2021.02.009Test

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9a6c7e6f3e021b6ffb5f3109bc206aTest
http://europepmc.org/articles/PMC7889466Test

9

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites

المؤلفون: Shaowei Zhang, Robert Schwarcz, Derren J. Heyes, Carlo Breda, Christopher David Edlin, Flaviano Giorgini, Nigel S. Scrutton, Girdhar Singh Deora, Colin Levy, Kevin D. Read, Marina Wright Muelas, Douglas B. Kell, David Leys, Benjamin P. Ross, Philip J. R. Day, Alex D Klausing, Stephen O’Hagan, Michiyo Sakuma

المصدر: Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Zhang, S, Sakuma, M, Deora, G S, Levy, C, Klausing, A, Breda, C, Read, K D, Ross, B P, Wright Muelas, M, Day, P, O'Hagan, S, Kell, D, Schwarcz, R, Leys, D, Heyes, D, Giorgini, F & Scrutton, N 2019, ' A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites ', Communications Biology . https://doi.org/10.1038/s42003-019-0520-5Test
Communications Biology
COMMUNICATIONS BIOLOGY

مصطلحات موضوعية: Kynurenine pathway, Metabolite, Medicine (miscellaneous), Pharmacology, Neuroprotection, Article, General Biochemistry, Genetics and Molecular Biology, Pathogenesis, Mice, 03 medical and health sciences, chemistry.chemical_compound, Kynurenine 3-Monooxygenase, 0302 clinical medicine, Manchester Institute of Biotechnology, medicine, Animals, Neurodegeneration, Enzyme Inhibitors, lcsh:QH301-705.5, X-ray crystallography, 030304 developmental biology, 0303 health sciences, Drug discovery, business.industry, Brain, Neurodegenerative Diseases, Hydrogen Peroxide, Prodrug, medicine.disease, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Chemical biology, 3. Good health, chemistry, lcsh:Biology (General), Blood-Brain Barrier, General Agricultural and Biological Sciences, business, 030217 neurology & neurosurgery, Kynurenine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cef15ca27e150c8aaa51693da774887Test
http://link.springer.com/article/10.1038/s42003-019-0520-5Test

10

Dysfunction of RAB39B-Mediated Vesicular Trafficking in Lewy Body Diseases

المؤلفون: Flaviano Giorgini, Tiago F. Outeiro, Susanna Campesan, David J. Koss

المصدر: Movement disorders 36(8), 1744-1758 (2021). doi:10.1002/mds.28605

مصطلحات موضوعية: 0301 basic medicine, Lewy Body Disease, Neurite, Endosome, alpha-synuclein, GTPase, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, genetics [Lewy Body Disease], genetics [Parkinson Disease], medicine, Humans, endocytosis, ddc:610, metabolism [alpha-Synuclein], Alpha-synuclein, Lewy body, RAB39B, Autophagy, Neurodegeneration, neurodegeneration, Parkinson Disease, Lewy body diseases, medicine.disease, metabolism [Lewy Bodies], metabolism [rab GTP-Binding Proteins], 030104 developmental biology, Neurology, chemistry, rab GTP-Binding Proteins, alpha-Synuclein, genetics [alpha-Synuclein], Lewy Bodies, Neurology (clinical), Rab, genetics [rab GTP-Binding Proteins], Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174a93c41786ddafd79e4ed29cf4a7d4Test
https://pub.dzne.de/record/155579Test

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