Development and Evaluation of Maze-Like Puzzle Games to Assess Cognitive and Motor Function in Aging and Neurodegenerative Diseases

التفاصيل البيبلوغرافية
العنوان: Development and Evaluation of Maze-Like Puzzle Games to Assess Cognitive and Motor Function in Aging and Neurodegenerative Diseases
المؤلفون: Tobias Nef, Alvin Chesham, Narayan Schütz, Angela Amira Botros, Tim Vanbellingen, Jean-Marc Burgunder, Julia Müllner, René Martin Müri, Prabitha Urwyler
المصدر: Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 12 (2020)
Nef, Tobias; Chesham, Alvin; Schütz, Narayan; Botros, Angela Amira; Vanbellingen, Tim; Burgunder, Jean-Marc; Müllner, Julia; Müri, René Martin; Urwyler, Prabitha (2020). Development and Evaluation of Maze-Like Puzzle Games to Assess Cognitive and Motor Function in Aging and Neurodegenerative Diseases. Frontiers in aging neuroscience, 12(87), p. 87. Frontiers Research Foundation 10.3389/fnagi.2020.00087 <http://dx.doi.org/10.3389/fnagi.2020.00087Test>
بيانات النشر: Frontiers Media SA, 2020.
سنة النشر: 2020
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Aging, Cognitive Neuroscience, 610 Medicine & health, Disease, Motor function, lcsh:RC321-571, cognitive assessment, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Age groups, medicine, neurodegenerative diseases, puzzle video games, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, Psychomotor learning, Neurodegeneration, Neuropsychology, Cognition, medicine.disease, maze task, 030104 developmental biology, 570 Life sciences, biology, Cognitive Assessment System, 030217 neurology & neurosurgery, Neuroscience
الوصف: There is currently a need for engaging, user-friendly, and repeatable tasks for assessment of cognitive and motor function in aging and neurodegenerative diseases. This study evaluated the feasibility of a maze-like Numberlink puzzle game in assessing differences in game-based measures of cognition and motor function due to age and neurodegenerative diseases. Fifty-five participants, including young (18–31 years, n = 18), older (64–79 years, n = 14), and oldest adults (86–98 years, n = 14), and patients with Parkinson’s (59–76 years, n = 4) and Huntington’s disease (HD; 35–66 years, n = 5) played different difficulty levels of the Numberlink puzzle game and completed usability questionnaires and tests for psychomotor, attentional, visuospatial, and constructional and executive function. Analyses of Numberlink game-based cognitive (solving time and errors) and motor [mean velocity and movement direction changes (MDC)] performance metrics revealed statistically significant differences between age groups and between patients with HD and older adults. However, patients with Parkinson’s disease (PD) did not differ from older adults. Correlational analyses showed significant associations between game-based performance and movement metrics and performance on neuropsychological tests for psychomotor, attentional, visuospatial, and constructional and executive function. Furthermore, varying characteristics of the Numberlink puzzle game succeeded in creating graded difficulty levels. Findings from this study support recent suggestions that data from a maze-like puzzle game provide potential “digital biomarkers” to assess changes in psychomotor, visuoconstructional, and executive function related to aging and neurodegeneration. In particular, game-based movement measures from the maze-like puzzle Numberlink games are promising as a tool to monitor the progression of motor impairment in neurodegenerative diseases. Further studies are needed to more comprehensively establish the cognitive validity and test–retest reliability of using Numberlink puzzles as a valid cognitive assessment tool.
وصف الملف: application/pdf
اللغة: English
تدمد: 1663-4365
DOI: 10.3389/fnagi.2020.00087
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09181e458b90de0ed80bf6d8a2e8802cTest
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....09181e458b90de0ed80bf6d8a2e8802c
قاعدة البيانات: OpenAIRE
الوصف
تدمد:16634365
DOI:10.3389/fnagi.2020.00087