نتائج البحث - "egfr inhibitors"

1

p85β alters response to EGFR inhibitor in ovarian cancer through p38 MAPK-mediated regulation of DNA repair

المؤلفون: Victor Cy Mak, Ling Rao, Yuan Zhou, Xinran Li, Lydia W.T. Cheung, Sai Wah Tsao

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 7, Pp 718-730 (2021)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.disease_cause, p38 Mitogen-Activated Protein Kinases, PI3K, Mice, 0302 clinical medicine, Epidermal growth factor receptor, RC254-282, EGFR inhibitors, Ovarian Neoplasms, biology, Disease Management, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Class Ia Phosphatidylinositol 3-Kinase, ErbB Receptors, Gene Expression Regulation, Neoplastic, Erlotinib, 030220 oncology & carcinogenesis, Female, Disease Susceptibility, Signal Transduction, medicine.drug, Original article, DNA Copy Number Variations, DNA damage, DNA repair, p38 MAPK, Models, Biological, 03 medical and health sciences, Cell Line, Tumor, DNA Repair Protein, p85 regulatory subunit, medicine, Animals, Humans, Protein Kinase Inhibitors, business.industry, medicine.disease, Disease Models, Animal, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, biology.protein, Ovarian cancer, Carcinogenesis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ecad4c612d528a8bee41b800d44cefTest
http://www.sciencedirect.com/science/article/pii/S1476558621000348Test

2

Foxq1 promotes metastasis of nasopharyngeal carcinoma by inducing vasculogenic mimicry via the EGFR signaling pathway

المؤلفون: Xuemin Ma, Yunfan Luo, Xiaoxiao Yu, Xiang-Ping Li, Juan Lu, Jie Wang, Fan Wang, Xiaohong Peng, Xiong Liu

المصدر: Cell Death and Disease, Vol 12, Iss 5, Pp 1-16 (2021)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunology, Article, Metastasis, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Drug Delivery Systems, medicine, Nimotuzumab, Humans, Vasculogenic mimicry, Neoplasm Metastasis, Head and neck cancer, EGFR inhibitors, Nasopharyngeal Carcinoma, QH573-671, business.industry, Promoter, Forkhead Transcription Factors, Nasopharyngeal Neoplasms, Cell Biology, medicine.disease, ErbB Receptors, stomatognathic diseases, 030104 developmental biology, Nasopharyngeal carcinoma, 030220 oncology & carcinogenesis, Drug delivery, Cancer research, Erlotinib, business, Cytology, Tumour angiogenesis, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4635294b85579aef868158d2f41a73bTest
https://doaj.org/article/3c91e31f98d64886a99973a8e48f9875Test

3

Third‐generation EGFR inhibitor HS ‐10296 in combination with famitinib, a multi‐targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR ‐mutant non‐small cell lung cancer cells

المؤلفون: Mi Zhang, Haitian Quan, Yun Li, Haoyu Fu, Li Fu, Liguang Lou

المصدر: Thoracic Cancer. 12:1210-1218

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7e142a9e73e3bf49a2269d1fe7041408Test
https://doi.org/10.1111/1759-7714.13902Test

4

Optimized EGFR Blockade Strategies in EGFR Addicted Gastroesophageal Adenocarcinomas

المؤلفون: Salvatore Siena, Daniel Moya-Rull, Andrea Sartore-Bianchi, Emanuele Rausa, Annalisa Petrelli, Annunziata Gloghini, Brian M. Alexander, Daniela Conticelli, Asa Dahle-Smith, Sara Erika Bellomo, Filippo Pietrantonio, J. Lee, Siraj M. Ali, Giovanni Sgroi, Vincent A. Miller, Federica Morano, Salvatore Corallo, Uberto Fumagalli, Silvia Giordano, Maria Di Bartolomeo, Caterina Marchiò, Giovanni de Manzoni, Anna Sapino, Antonino Sottile, Stefano De Pascale, Gian Luca Baiocchi, Laura D'Errico, Silvia Marsoni, Rossella Reddavid, Simona Corso, Michele Prisciandaro, Stefania Durando, Zosia Miedzybrodzka, Cristina Migliore, Alexa B. Schrock, Russell D. Petty, Maria Apicella, Jeffrey S. Ross, Maurizio Degiuli, Sarah Molfino, Maria Bencivenga, Stefano Ughetto

المصدر: Clinical Cancer Research. 27:3126-3140

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Esophageal Neoplasms, medicine.medical_treatment, Adenocarcinoma, medicine.disease_cause, Antibodies, Targeted therapy, Cohort Studies, Mice, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, Trastuzumab, Internal medicine, Monoclonal, Tumor Cells, Cultured, medicine, Animals, Humans, Molecular Targeted Therapy, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, EGFR inhibitors, Cultured, Everolimus, Cetuximab, business.industry, TOR Serine-Threonine Kinases, Antibodies, Monoclonal, Cancer, Protein-Tyrosine Kinases, medicine.disease, Tumor Cells, ErbB Receptors, HEK293 Cells, 030104 developmental biology, 030220 oncology & carcinogenesis, KRAS, business, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e624f3cd608d4d41c6dba93cb628009Test
https://doi.org/10.1158/1078-0432.ccr-20-0121Test

5

Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression

المؤلفون: Wei-Chung Cheng, Yuh Pyng Sher, Chia-Chien Lo, Guan-Chin Tseng, Yu-Kai Huang, Ching Chan Lin, Jin-Yuan Shih, Ting-Ting Kuo, K. S. Clifford Chao, Jennifer L. Hsu, Tzu-Hung Hsiao, Liang-Chuan Lai, Xian Sun, Mien Chie Hung, Chia-Fong Cho, Pei-Chih Lee, Yu-Huei Liu, Yu Sen Lin, Wei Chao Chang

المصدر: Theranostics

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, BASP1, Medicine (miscellaneous), Kaplan-Meier Estimate, combination therapy, Mice, 0302 clinical medicine, Arsenic Trioxide, Antineoplastic Combined Chemotherapy Protocols, Medicine, EGFR-TKI acquired resistance, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Lung, EGFR inhibitors, Feedback, Physiological, Brain Neoplasms, Brain, Prognosis, ErbB Receptors, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Adenocarcinoma, Tyrosine kinase, Research Paper, Signal Transduction, Brain Acid Soluble Protein 1, Adenocarcinoma of Lung, Nerve Tissue Proteins, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Lung cancer, Protein Kinase Inhibitors, business.industry, Gene Expression Profiling, Cell Membrane, Membrane Proteins, medicine.disease, lung adenocarcinoma, Xenograft Model Antitumor Assays, Repressor Proteins, 030104 developmental biology, Membrane protein, Tumor progression, Drug Resistance, Neoplasm, Tissue Array Analysis, Mutation, Proteolysis, Cancer research, business, Brain metastasis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2344f6f2a08d9c4a6bfcefe84f2dbda9Test
http://europepmc.org/articles/PMC7532684Test

6

Fibroblast growth factor receptor 4 increases epidermal growth factor receptor (EGFR) signaling by inducing amphiregulin expression and attenuates response to EGFR inhibitors in colon cancer

المؤلفون: Jo-Heon Kim, Eun Gene Sun, Chaeyong Jung, Kyung Keun Kim, Ji-Na Choi, Jun-Eul Hwang, Sang-Hee Cho, Hyun-Jeong Shim, Hyeong-Rok Kim, D.E. Kim, Chang-Soo Hong, Woo Kyun Bae, Ik-Joo Chung, Kyung-Hyun Ryu

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Colorectal cancer, EGFR, Cetuximab, Amphiregulin, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Cell, Molecular, and Stem Cell Biology, Cell Line, Tumor, medicine, Humans, ERBB3, Receptor, Fibroblast Growth Factor, Type 4, Epidermal growth factor receptor, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Protein Kinase Inhibitors, EGFR inhibitors, biology, business.industry, Gene Expression Profiling, Cancer, General Medicine, Fibroblast growth factor receptor 4, Original Articles, medicine.disease, AREG, digestive system diseases, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, colon cancer, 030220 oncology & carcinogenesis, Colonic Neoplasms, Cancer research, biology.protein, FGFR4, Original Article, business, Proto-Oncogene Proteins c-akt, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7135087a80d25740ca044fcde67a6da7Test
http://europepmc.org/articles/PMC7469799Test

7

miR-206 inhibits liver cancer stem cell expansion by regulating EGFR expression

المؤلفون: Wei Wang, Xingyang Zhong, Caifeng Liu, Jun Li, Feng Xu, Junhua Lu

المصدر: Cell Cycle

مصطلحات موضوعية: 0301 basic medicine, Carcinoma, Hepatocellular, Carcinogenesis, Down-Regulation, Apoptosis, Biology, Transfection, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Gefitinib, Biomarkers, Tumor, medicine, Humans, Epidermal growth factor receptor, Cell Self Renewal, Molecular Biology, EGFR inhibitors, Liver Neoplasms, Epithelial cell adhesion molecule, Hep G2 Cells, Cell Biology, Cell Dedifferentiation, HCCS, medicine.disease, digestive system diseases, ErbB Receptors, MicroRNAs, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Cancer research, biology.protein, Stem cell, Liver cancer, Signal Transduction, Research Paper, Developmental Biology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc59e93f0b8f97f8fb68024c6fe6a826Test
https://doi.org/10.1080/15384101.2020.1739808Test

8

Feedback activation of EGFR is the main cause for STAT3 inhibition-irresponsiveness in pancreatic cancer cells

المؤلفون: Jiayuh Lin, Chenglong Li, Zhiguo Liu, Ri Cui, Liangxing Wang, Lehe Yang, Chengguang Zhao, Guang Liang, Youqun Xiang, Huang Xiaoying, Xiaojing Du, Congying Xie, Yun Yu, Feng Zhou

المصدر: Oncogene. 39:3997-4013

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8b5bbf5117b09383646c8d43ff57a24aTest
https://doi.org/10.1038/s41388-020-1271-yTest

9

EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy

المؤلفون: Shuli Liu, Ling Zhang, Jingzhou Hu, Houyu Ju, Shengming Xu, Guoxin Ren, Yang Wang, Yong Han, Xiangkai Zhang, Liu Liu, Weimin Ye, Weiya Xia, Zhiyuan Zhang

المصدر: Theranostics

مصطلحات موضوعية: Male, 0301 basic medicine, Carcinogenesis, Medicine (miscellaneous), medicine.disease_cause, HNSCC, Epiregulin, Mice, 0302 clinical medicine, Epidermal growth factor receptor, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), EGFR inhibitors, Aged, 80 and over, Gene knockdown, biology, Middle Aged, Up-Regulation, ErbB Receptors, Gene Expression Regulation, Neoplastic, Erlotinib, Head and Neck Neoplasms, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Female, Signal transduction, Research Paper, medicine.drug, Adult, EGFR, Proto-Oncogene Proteins c-myc, Erlotinib Hydrochloride, 03 medical and health sciences, Cell Line, Tumor, C-Myc, medicine, Animals, Humans, neoplasms, Aged, Squamous Cell Carcinoma of Head and Neck, business.industry, Gene Expression Profiling, medicine.disease, Xenograft Model Antitumor Assays, Head and neck squamous-cell carcinoma, stomatognathic diseases, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6b3cfe9747cc5cfa3c818bf64aa768Test
https://doi.org/10.7150/thno.47176Test

10

HUNK phosphorylates EGFR to regulate breast cancer metastasis

المؤلفون: Elizabeth S. Yeh, Kendall Phelps-Polirer, Christina J. Williams, Kent Armeson, Scott T. Eblen, Ivan P. Dingle, Elizabeth G. Hill, Carly Bess Williams, Matthew J. Rhett

المصدر: Oncogene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342c84afe804ee741cc87125f4fcf258Test
http://europepmc.org/articles/PMC6989402Test

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