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المؤلفون: Jörg R. P. Geiger, Henrike Planert, Franz Xaver Mittermaier, Henrik Alle, Ulf C. Schneider, Yangfan Peng
المصدر: eLife
eLife, Vol 8 (2019)مصطلحات موضوعية: Patch-Clamp Techniques, Mouse, QH301-705.5, Computer science, Science, Cortical slice, General Biochemistry, Genetics and Molecular Biology, Software, Automated patch clamp, Humans, Patch clamp, Biology (General), Throughput (business), microcircuit, Neurons, General Immunology and Microbiology, Subthreshold conduction, business.industry, General Neuroscience, multipatch, Pipette, Brain, Usability, Small sample, General Medicine, human physiology, Tools and Resources, connectivity, Medicine, Rat, Nerve Net, business, automated patch-clamp, human cortex, Neuroscience, Human
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455ff15bf59cc2957b125ea55e0bbbcdTest
https://doi.org/10.7554/elife.48178Test -
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المؤلفون: Kirstine Calloe, Søren Friis, Dagmar S Trachsel, Salomé Rognant, Catherine Shaughnessy, Dan A. Klaerke
المصدر: Research in Veterinary Science. 123:239-246
مصطلحات موضوعية: Drug, 0303 health sciences, General Veterinary, Diphenhydramine hydrochloride, 040301 veterinary sciences, business.industry, media_common.quotation_subject, 04 agricultural and veterinary sciences, Drug interaction, Pharmacology, Cyproheptadine Hydrochloride, 0403 veterinary science, 03 medical and health sciences, Acepromazine, Automated patch clamp, medicine, Repolarization, Patch clamp, business, 030304 developmental biology, media_common, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::89314c49504f3e42e329248451756166Test
https://doi.org/10.1016/j.rvsc.2019.01.009Test -
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المصدر: PLoS ONE, Vol 16, Iss 3, p e0243645 (2021)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Physiology, Action Potentials, Biochemistry, Ion Channels, 0302 clinical medicine, Calcium Channels, N-Type, Automated patch clamp, Transient Transfection Assay, Cricetinae, Medicine and Health Sciences, Membrane Electrophysiology, Analgesics, Multidisciplinary, Chemistry, Physics, NAV1.7 Voltage-Gated Sodium Channel, Transfection, Electrophysiology, Bioassays and Physiological Analysis, Physical Sciences, 293T cells, Cell lines, Medicine, Biological cultures, Research Article, Science, Biophysics, Neurophysiology, Pain, CHO Cells, Research and Analysis Methods, Calcium Phosphate Transfection, 03 medical and health sciences, Signs and Symptoms, Cricetulus, FuGENE, Animals, Humans, Patch clamp, Molecular Biology Techniques, Molecular Biology, Ion channel, Voltage-gated ion channel, Sodium channel, Electrophysiological Techniques, Biology and Life Sciences, Proteins, High-Throughput Screening Assays, 030104 developmental biology, HEK293 Cells, Microscopy, Fluorescence, Lipofectamine, Calcium Channels, Clinical Medicine, Patch Clamp Techniques, 030217 neurology & neurosurgery, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b541cc5ff952fab70a9d767a58884ec2Test
https://doaj.org/article/f089b070a4b446cb8df4ca680b12c11cTest -
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المؤلفون: Abby Sewell, Glenn E. Kirsch, Caiyun Wu, Arianne L. Motter, Fedorov Nikolai, Yuri A. Kuryshev, Lucas C. Armstrong, Michael S. Orr, Zhiqi Liu, Carmine Leggett
المصدر: Slas Discovery
مصطلحات موضوعية: 0301 basic medicine, Agonist, Patch-Clamp Techniques, medicine.drug_class, Genetic Vectors, Gene Expression, Receptors, Nicotinic, Pharmacology, Nucleus accumbens, Transfection, Biochemistry, Cell Line, Analytical Chemistry, Small Molecule Libraries, Nicotine, 03 medical and health sciences, 0302 clinical medicine, Automated patch clamp, Drug Discovery, medicine, Humans, Patch clamp, nicotinic acetylcholine receptor, Cloning, Molecular, Original Research, Acetylcholine receptor, Chemistry, Electrophysiological Phenomena, High-Throughput Screening Assays, Protein Subunits, Nicotinic acetylcholine receptor, 030104 developmental biology, Nicotinic agonist, ion channel, electrophysiological screening, Molecular Medicine, automated patch clamp, Ion Channel Gating, 030217 neurology & neurosurgery, Biotechnology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1e31ebce6f9b777c6201a00c062cd3Test
https://doi.org/10.1177/2472555217696794Test -
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المصدر: Simo Vicens, R, Sauter, D R P, Grunnet, M, Diness, J G & Bentzen, B H 2017, ' Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels ', European Journal of Pharmacology, vol. 803, pp. 118-123 . https://doi.org/10.1016/j.ejphar.2017.03.039Test
European Journal of Pharmacologyمصطلحات موضوعية: Faculty of Health and Medical Sciences, 0301 basic medicine, Small-Conductance Calcium-Activated Potassium Channels, antiarrhythmic drug, Dofetilide, Propafenone, 030204 cardiovascular system & hematology, Pharmacology, SK channel, 03 medical and health sciences, 0302 clinical medicine, kca2 channel, calcium-activated potassium channel, Atrial Fibrillation, medicine, Humans, Sinus rhythm, Patch clamp, Chemistry, Atrial fibrillation, Cardiac action potential, medicine.disease, Calcium-activated potassium channel, 3. Good health, HEK293 Cells, 030104 developmental biology, automated patch clamp, Anti-Arrhythmia Agents, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f591c9b789054b93669329815b683aTest
https://doi.org/10.1016/j.ejphar.2017.03.039Test -
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المؤلفون: Michael M. Poe, Nina Y. Yuan, Christopher M. Witzigmann, Leggy A. Arnold, Douglas C. Stafford, James M. Cook
المصدر: Journal of Pharmacological and Toxicological Methods. 82:109-114
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Agonist, medicine.drug_class, GABAA receptor, Allosteric regulation, Long-term potentiation, Biology, Toxicology, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Automated patch clamp, medicine, GABAergic, Patch clamp, Induced pluripotent stem cell, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3855ddab73e494432f8f613ce9564cf4Test
https://doi.org/10.1016/j.vascn.2016.08.006Test -
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المؤلفون: Sylvain Feliciangeli, Vincent Probst, B.B. Ribeiro de Oliveira Mendes, Franck C. Chatelain, B. Ollivier, Jérôme Montnach, F. Kyndt, S. Nicolas, Florian Lesage, Gildas Loussouarn, Isabelle Denjoy, M. De Waard
المصدر: Archives of Cardiovascular Diseases Supplements. 12:257
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, biology, business.industry, High-throughput screening, Electroporation, hERG, Transfection, Computational biology, Potassium channel, Automated patch clamp, FuGENE, biology.protein, Medicine, cardiovascular diseases, Patch clamp, Cardiology and Cardiovascular Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::48b64222c03c0b877391f85d739f4066Test
https://doi.org/10.1016/j.acvdsp.2020.03.138Test -
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المؤلفون: Takayuki Oka, Alison Obergrussberger, Søren Friis, Hatsue Furukawa, Nina Brinkwirth, Sonja Stoelzle-Feix, Atsushi Ohtsuki, Yuka Hasegawa, Kiyoshi Takasuna, Niels Fertig, Masafumi Doi, Nadine Becker
المصدر: Journal of Pharmacological and Toxicological Methods. 105:106884
مصطلحات موضوعية: ERG1 Potassium Channel, Patch-Clamp Techniques, hERG, Drug Evaluation, Preclinical, Dofetilide, CHO Cells, 030204 cardiovascular system & hematology, Polypropylenes, Toxicology, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Automated patch clamp, Drug Discovery, Phenethylamines, medicine, Animals, Humans, Patch clamp, Polytetrafluoroethylene, Ion channel, Pharmacology, Sulfonamides, biology, Chemistry, Drug discovery, Safety pharmacology, Reproducibility of Results, Arrhythmias, Cardiac, Cardiovascular Agents, Heart, Astemizole, Reference Standards, Benchmarking, HEK293 Cells, Calibration, biology.protein, Terfenadine, medicine.drug, Biomedical engineering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a232b0cdc1e86e3a7f7560e3afb49141Test
https://doi.org/10.1016/j.vascn.2020.106884Test -
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المؤلفون: Sonja Stölzle-Feix, Nadine Becker, Alison Obergrussberger, Andrea Brüggemann, Clemens Möller, Niels Fertig
المصدر: Channels
مصطلحات موضوعية: Patch-Clamp Techniques, Biophysics, Quantitative Structure-Activity Relationship, Nanotechnology, cardiomyocytes, Review, Biochemistry, Ion, Cell membrane, Small Molecule Libraries, action potential, Automated patch clamp, safety pharmacology, Drug Discovery, medicine, Potassium Channel Blockers, Animals, Humans, Patch clamp, Integral membrane protein, Ion channel, Chemistry, screening, ion channels, temperature, High-Throughput Screening Assays, Electrophysiology, medicine.anatomical_structure, impedance, Flux (metabolism), Sodium Channel Blockers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2d55d35260852adabdde2d95a3d964Test
http://europepmc.org/articles/PMC4850050Test -
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المؤلفون: Mika Sugiura, Chizuko Nishizawa-Harada, Tadashi Kimura, Kyoko Kikuchi
المصدر: Biotechnology Reports, Vol 7, Iss C, Pp 17-23 (2015)
Biotechnology Reportsمصطلحات موضوعية: Screen method, lcsh:Biotechnology, Biology, medicine.disease_cause, Applied Microbiology and Biotechnology, Article, Planar patch clamp, Microbiology, Automated patch clamp, lcsh:TP248.13-248.65, medicine, Escherichia coli, Giant spheroplast, Patch clamp, Ion channel, Human Kv2.1, 4-AP (4-aminopyridine), fungi, Spheroplast, TEA (tetraethylammonium), Electrophysiology, Drug screening, Biophysics, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503d1e009dd3ba587d1302ff3ef61e82Test