دورية أكاديمية
The safety of warfarin therapy in the nursing home setting.
| العنوان: | The safety of warfarin therapy in the nursing home setting. |
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| المؤلفون: | Gurwitz, Jerry H., Field, Terry S., Radford, Martha J., Harrold, Leslie R., Becker, Richard C., Reed, George W., DeBellis, Kristin R., Moldoff, Jason A., Verzier, Nancy |
| المساهمون: | Department of Medicine, Division of Rheumatology, Department of Medicine, Division of Geriatric Medicine, Meyers Primary Care Institute |
| المصدر: | The American journal of medicine ; 120 ; 6 |
| بيانات النشر: | Excerpta Medica |
| سنة النشر: | 2022 |
| المجموعة: | University of Massachusetts, Medical School: eScholarship@UMMS |
| مصطلحات موضوعية: | Aged, 80 and over, Anticoagulants, Drug Monitoring, Drug Utilization, Female, Hemorrhage, Homes for the Aged, Humans, International Normalized Ratio, Male, Medication Errors, Nursing Homes, Warfarin, Health Services Research, Medicine and Health Sciences |
| الوصف: | PURPOSE: We examined the preventability of adverse warfarin-related events and potential adverse warfarin-related events ("near misses") in the nursing home setting. METHODS: We performed a cohort study of all long-term care residents of 25 nursing homes (bed size range, 90-360) in Connecticut during a 12-month observation period. The total number of residents in these facilities ranged from 2946 to 3212 per quarter. There were 490 residents who received warfarin therapy. Possible warfarin-related incidents were detected by quarterly retrospective review of nursing home records by trained nurse abstractors. Each incident was independently classified by 2 physician-reviewers to determine whether it constituted a warfarin-related event, its severity, and its preventability. The primary outcome was an adverse warfarin-related event, defined as an injury associated with the use of warfarin. Potential adverse warfarin-related events were defined as situations in which the international normalized ratio (INR) was noted to be 4.5 or greater, an error in management was noted, but no injury occurred. We also assessed time in specified INR ranges per nursing home resident day on warfarin. RESULTS: Over the 12-month observation period, 720 adverse warfarin-related events and 253 potential adverse warfarin-related events were identified. Of the adverse warfarin-related events, 625 (87%) were characterized as minor, 82 (11%) were deemed serious, and 13 (2%) were life-threatening or fatal. Overall, 29% of the adverse warfarin-related events were judged to be preventable. Serious, life-threatening, or fatal events occurred at a rate of 2.49 per 100 resident-months; 57% of these more severe events were considered preventable. Errors resulting in preventable events occurred most often at the prescribing and monitoring stages of warfarin management. The percentages of time in the less than 2, 2 to 3, and more than 3 INR ranges were 36.5%, 49.6%, and 13.9%, respectively. CONCLUSIONS: The use of warfarin in the nursing home setting ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1555-7162 |
| العلاقة: | Link to article in PubMed; http://dx.doi.org/10.1016/j.amjmed.2006.07.045Test; Am J Med. 2007 Jun;120(6):539-44. Epub 2007 Apr 26.; http://hdl.handle.net/20.500.14038/37088Test; https://escholarship.umassmed.edu/meyers_pp/47Test; 1016857; meyers_pp/47 |
| الإتاحة: | https://doi.org/20.500.14038/37088Test https://doi.org/10.1016/j.amjmed.2006.07.045Test https://hdl.handle.net/20.500.14038/37088Test https://escholarship.umassmed.edu/meyers_pp/47Test |
| رقم الانضمام: | edsbas.8AB0862C |
| قاعدة البيانات: | BASE |
| تدمد: | 15557162 |
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