المؤلفون: Francesca Mancini, Ludovica Giorgini, Emanuela Teveroni, Alfredo Pontecorvi, Fabiola Moretti

المصدر: Frontiers in Oncology, Vol 11 (2021)

مصطلحات موضوعية: cancer therapy, p53, sex, estrogen, MDM2, MDM4, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2021.698946/fullTest; https://doaj.org/toc/2234-943XTest

الوصول الحر: https://doaj.org/article/3646eba3d79b4acf910919c4de8cfd28Test

المؤلفون: Rossella Lucà, Giorgia di Blasio, Daniela Gallo, Valentina Monteleone, Isabella Manni, Laura Fici, Marianna Buttarelli, Germana Ciolli, Marsha Pellegrino, Emanuela Teveroni, Silvia Maiullari, Alessandra Ciucci, Alessandro Apollo, Francesca Mancini, Maria Pia Gentileschi, Gian Franco Zannoni, Alfredo Pontecorvi, Giovanni Scambia, Fabiola Moretti

المصدر: Cancers, Vol 11, Iss 9, p 1349 (2019)

مصطلحات موضوعية: estrogen, chemosensitivity, MDM4, sexual dimorphism, intracellular trafficking, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/11/9/1349Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/d5f148dfb2704772800f15fa0c1ac9fcTest

المؤلفون: Emanuela Teveroni, Anna Rita Bizzarri, Ilaria Moscetti, Salvatore Cannistraro, Fabiola Moretti

المصدر: International journal of nanomedicine (Online) 11 (2016): 4221–4229. doi:10.2147/IJN.S114705
info:cnr-pdr/source/autori:Moscetti, Ilaria; Teveroni, Emanuela; Moretti, Fabiola; Bizzarri, Anna Rita; Cannistraro, Salvatore/titolo:MDM2-MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance/doi:10.2147%2FIJN.S114705/rivista:International journal of nanomedicine (Online)/anno:2016/pagina_da:4221/pagina_a:4229/intervallo_pagine:4221–4229/volume:11
International Journal of Nanomedicine

مصطلحات موضوعية: 0301 basic medicine, Kinetics, atomic force spectroscopy, Biophysics, Pharmaceutical Science, Cell Cycle Proteins, Bioengineering, Nanotechnology, Plasma protein binding, Microscopy, Atomic Force, Kinetic energy, Biomaterials, MDM4, 03 medical and health sciences, MDM2, International Journal of Nanomedicine, Proto-Oncogene Proteins, Drug Discovery, Humans, Surface plasmon resonance, Original Research, Range (particle radiation), Chemistry, Spectrum Analysis, Organic Chemistry, Force spectroscopy, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, General Medicine, Characterization (materials science), Dissociation constant, Immobilized Proteins, 030104 developmental biology, surface plasmon resonance, Protein Binding

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04eefce52c145b9ca2a1247ffbf5eda3Test
https://doi.org/10.2147/ijn.s114705Test

المؤلفون: Giovanni Scambia, Maria Pia Gentileschi, Alessandra Ciucci, Emanuela Teveroni, Alessandro Apollo, Giorgia di Blasio, Marianna Buttarelli, Francesca Mancini, Valentina Monteleone, Gian Franco Zannoni, Marsha Pellegrino, Fabiola Moretti, Alfredo Pontecorvi, Silvia Maiullari, Rossella Lucà, Laura Fici, Germana Ciolli, Isabella Manni, Daniela Gallo

المصدر: Cancers (Basel) 11 (2019). doi:10.3390/cancers11091349
info:cnr-pdr/source/autori:Lucà, Rossella; Blasio, Giorgia Di; Gallo, Daniela; Monteleone, Valentina; Manni, Isabella; Fici, Laura; Buttarelli, Marianna; Ciolli, Germana; Pellegrino, Marsha; Teveroni, Emanuela; Maiullari, Silvia; Ciucci, Alessandra; Apollo, Alessandro; Mancini, Francesca; Gentileschi, Maria Pia; Zannoni, Gian Franco; Pontecorvi, Alfredo; Scambia, Giovanni; Moretti, Fabiola/titolo:Estrogens counteract platinum-chemosensitivity by modifying the subcellular localization of MDM4/doi:10.3390%2Fcancers11091349/rivista:Cancers (Basel)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1349 (2019)

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Cancer Research, Programmed cell death, medicine.drug_class, Estrogen receptor, lcsh:RC254-282, Article, 03 medical and health sciences, MDM4, Sexual dimorphism, 0302 clinical medicine, In vivo, medicine, Chemosensitivity, Cisplatin, Fulvestrant, Chemistry, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Estrogen, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Intracellular, Intracellular trafficking, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f893d894f92128c0b1601f1bf909dadbTest
http://www.scopus.com/record/display.url?eid=2-s2.0-85073385969&origin=inwardTest

المؤلفون: Francesca Mancini, Valentina Monteleone, Andrea Urbani, Emanuela Teveroni, Alfredo Pontecorvi, Marsha Pellegrino, Mara D'Onofrio, Massimiliano Mazzone, Luisa Pieroni, Giusy Di Conza, Fabiola Moretti, Ivan Arisi, Marianna Buttarelli

المصدر: Molecular cancer 16 (2017): 55. doi:10.1186/s12943-017-0626-7
info:cnr-pdr/source/autori:Mancini, Francesca; Teveroni, Emanuela; Di Conza, Giusy; Monteleone, Valentina; Arisi, Ivan; Pellegrino, Marsha; Buttarelli, Marianna; Pieroni, Luisa; D'Onofrio, Mara; Urbani, Andrea; Pontecorvi, Alfredo; Mazzone, Massimiliano; Moretti, Fabiola/titolo:MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability./doi:10.1186%2Fs12943-017-0626-7/rivista:Molecular cancer/anno:2017/pagina_da:55/pagina_a:/intervallo_pagine:55/volume:16
Molecular Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Genetically modified mouse, Cancer Research, mdm4, Cell Survival, Cell Cycle Proteins, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Cell Line, Mice, 03 medical and health sciences, Aminoacid, breast cancer, Neoplasms, Proto-Oncogene Proteins, cancer, Animals, Humans, Phosphorylation, Nutrient deprivation, PI3K/AKT/mTOR pathway, Cell Proliferation, P53, Kinase, Cell growth, Research, Ribosomal Protein S6 Kinases, TOR Serine-Threonine Kinases, Cell Cycle, Nuclear Proteins, Ribosomal Protein S6 Kinases, 70-kDa, Cell cycle, 70-kDa, 030104 developmental biology, Oncology, Cell culture, Multiprotein Complexes, MDM4, MTOR, Protein Binding, Signal Transduction, mTOR, Cancer research, Molecular Medicine, Signal transduction, metabolism

وصف الملف: Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb8808597bdd4d30b2ad10c8b513cebTest
https://doi.org/10.1186/s12943-017-0626-7Test

المؤلفون: Emilia Luca, Rossella Lucà, Riccardo Masetti, Silvia Soddu, S. Xiong, G. Lozano, Alfredo Pontecorvi, Luisa Pieroni, Valentina Monteleone, Francesca Mancini, Fabiola Moretti, Andrea Urbani, Laura Fici

المصدر: Oncogene (Basingstoke, Online) 35 (2016): 228–240. doi:10.1038/onc.2015.76
info:cnr-pdr/source/autori:Mancini F, Pieroni L, Monteleone V, Lucà R, Fici L, Luca L, Urbani A, Xiong S, Soddu S, Masetti R, Lozano G, Pontecorvi A, Moretti F./titolo:MDM4%2FHIPK2%2Fp53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response/doi:10.1038%2Fonc.2015.76/rivista:Oncogene (Basingstoke, Online)/anno:2016/pagina_da:228/pagina_a:240/intervallo_pagine:228–240/volume:35
Oncogene

مصطلحات موضوعية: 0301 basic medicine, p53, Cancer Research, Cytoplasm, MDMX, DNA damage, Ubiquitin-Protein Ligases, Molecular Sequence Data, Cell Cycle Proteins, Mice, Transgenic, HIPK2, Protein Serine-Threonine Kinases, 03 medical and health sciences, MDM4, CELL-CYCLE ARREST, Downregulation and upregulation, Proto-Oncogene Proteins, Genetics, Serine, Animals, Humans, Nuclear protein, Molecular Biology, Psychological repression, Settore BIO/10 - BIOCHIMICA, biology, Base Sequence, INTERACTING PROTEIN KINASE-2, Kinase, apoptosis, Nuclear Proteins, Epithelial Cells, Settore MED/13 - ENDOCRINOLOGIA, Fibroblasts, HCT116 Cells, Molecular biology, Mice, Inbred C57BL, 030104 developmental biology, Ser46, biology.protein, Mdm2, Phosphorylation, Original Article, Female, Tumor Suppressor Protein p53, Carrier Proteins, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa886410acf884c1204be867c8841783Test
http://hdl.handle.net/10807/94151Test

المؤلفون: Rossella Lucà, Alfredo Pontecorvi, Fabiola Moretti, Germana Ciolli, Marsha Pellegrino, Emanuela Teveroni

مصطلحات موضوعية: 0301 basic medicine, MDMX, Peptidomimetic, Antineoplastic Agents, Cell Cycle Proteins, Computational biology, Pharmacology, Biology, P53 mdm2, anticancer peptide, Patents as Topic, 03 medical and health sciences, MDM4, therapy-resistance, 0302 clinical medicine, MDM2, Neoplasms, Proto-Oncogene Proteins, Drug Discovery, Animals, Humans, p53 reactivation therapy, Treatment resistance, Drug Discovery3003 Pharmaceutical Science, dual-inhibitor, Nuclear Proteins, P53 Tumor Suppressor, Proto-Oncogene Proteins c-mdm2, Settore MED/13 - ENDOCRINOLOGIA, General Medicine, Small molecule, 030104 developmental biology, Reduced toxicity, 030220 oncology & carcinogenesis, Drug Design, Peptidomimetics, Tumor Suppressor Protein p53, Peptides, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7d0f066f84488c188276bc31097a7eTest
http://hdl.handle.net/10807/91872Test

المؤلفون: Alfredo Pontecorvi, Francesco Trimarchi, Marianna Buttarelli, Francesca Mancini, Fabiola Moretti, Giusy Di Conza

المصدر: Cell cycle (Georget. Tex.) 11 (2012): 749–760.
info:cnr-pdr/source/autori:Giusy Di Conza 1,2; Francesca Mancini 1,3; Marianna Buttarelli 1; Alfredo Pontecorvi 3; Francesco Trimarchi 2; Fabiola Moretti 1/titolo:MDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage/doi:/rivista:Cell cycle (Georget. Tex.)/anno:2012/pagina_da:749/pagina_a:760/intervallo_pagine:749–760/volume:11

مصطلحات موضوعية: Conformational change, MDMX, mdm4, DNA damage, Ubiquitin-Protein Ligases, Regulator, Cell Line, Mice, Proto-Oncogene Proteins, Genetic model, Animals, Humans, Immunoprecipitation, Molecular Biology, Cells, Cultured, biology, Protein Stability, Reverse Transcriptase Polymerase Chain Reaction, Proto-Oncogene Proteins c-mdm2, Settore MED/13 - ENDOCRINOLOGIA, Cell Biology, Ubiquitin ligase, Cell biology, Proteasome, Biochemistry, biology.protein, Mdm2, Tumor Suppressor Protein p53, DNA Damage, Protein Binding, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0398ef48e1fcac24b3ce80b2446a04b1Test
http://hdl.handle.net/10807/12478Test

المؤلفون: Fabiola Moretti

المصدر: Molecular & Cellular Oncology 3 (2016): e1066923. doi:10.1080/23723556.2015.1066923
info:cnr-pdr/source/autori:Fabiola Moretti/titolo:Novel insights about the MDM2%2FMDM4 heterodimer/doi:10.1080%2F23723556.2015.1066923/rivista:Molecular & Cellular Oncology/anno:2016/pagina_da:e1066923/pagina_a:/intervallo_pagine:e1066923/volume:3

مصطلحات موضوعية: p53, 0301 basic medicine, Cancer Research, MDMX, DNA damage, Apoptosis, Biology, Molecular biology, Cell biology, MDM4, 03 medical and health sciences, DDB1, 030104 developmental biology, MDM2, heterodimer, Transcriptional repression, biology.protein, Molecular Medicine, Mdm2, Phosphorylation, Protein kinase A, Author's View

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647d746d9b18a084a4621ec651aaba11Test
https://doi.org/10.1080/23723556.2015.1066923Test

المؤلفون: Francesca Mancini, Giusy Di Conza, Marsha Pellegrino, Cinzia Rinaldo, Andrea Prodosmo, Simona Giglio, Igea D'Agnano, Fulvio Florenzano, Lara Felicioni, Fiamma Buttitta, Antonio Marchetti, Ada Sacchi, Alfredo Pontecorvi, Silvia Soddu, Fabiola Moretti

المساهمون: Mancini, Francesca, Di Conza, Giusy, Pellegrino, Marsha, Rinaldo, Cinzia, Prodosmo, Andrea, Giglio, Simona, D'Agnano, Igea, Florenzano, Fulvio, Felicioni, Lara, Buttitta, Fiamma, Marchetti, Antonio, Sacchi, Ada, Pontecorvi, Alfredo, Soddu, Silvia, Moretti, Fabiola

مصطلحات موضوعية: mdm4, mdmx, p53, bcl2, p53ser46(P), mitochondrial apoptosis

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/19521340; info:eu-repo/semantics/altIdentifier/wos/WOS:000267806700011; volume:28; issue:13; firstpage:1926; lastpage:1939; numberofpages:14; journal:EMBO JOURNAL; http://hdl.handle.net/11573/1122314Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-67650501132

الإتاحة: https://doi.org/10.1038/emboj.2009.154Test
http://hdl.handle.net/11573/1122314Test