المؤلفون: Francesca Mancini, Ludovica Giorgini, Emanuela Teveroni, Alfredo Pontecorvi, Fabiola Moretti

المصدر: Frontiers in Oncology, Vol 11 (2021)

مصطلحات موضوعية: cancer therapy, p53, sex, estrogen, MDM2, MDM4, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2021.698946/fullTest; https://doaj.org/toc/2234-943XTest

الوصول الحر: https://doaj.org/article/3646eba3d79b4acf910919c4de8cfd28Test

المؤلفون: Susanna Dolci, Bruno Botta, Pamela Bielli, Deborah Quaglio, Eugenia Guida, Fabiola Moretti, Mattia Mori, Marco Barchi, Francesca Ghirga, Federica Todaro, Cinzia Caggiano, Paola Grimaldi, Emmanuele A. Jannini, Pellegrino Rossi

المصدر: Cell Death Discovery 6 (2020). doi:10.1038/s41420-020-00345-4
info:cnr-pdr/source/autori:Caggiano, Cinzia; Guida, Eugenia; Todaro, Federica; Bielli, Pamela; Mori, Mattia; Ghirga, Francesca; Quaglio, Deborah; Botta, Bruno; Moretti, Fabiola; Grimaldi, Paola; Rossi, Pellegrino; Jannini, Emmanuele A.; Barchi, Marco; Dolci, Susanna/titolo:Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells/doi:10.1038%2Fs41420-020-00345-4/rivista:Cell Death Discovery/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:6
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-15 (2020)

مصطلحات موضوعية: 0301 basic medicine, p53, Cancer Research, Nucleolus, Immunology, tumor cells, lcsh:RC254-282, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Testicular cancer, Downregulation and upregulation, MDM2, Transcription (biology), Target identification, Null cell, RNA polymerase I, E2F1, sempervirin, lcsh:QH573-671, Settore BIO/16, lcsh:Cytology, Cell growth, Chemistry, Sempervirine, RNA polymerase, Cell Biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell biology, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e667e20866f31450db2b3bb2d7347753Test
http://www.cnr.it/prodotto/i/449477Test

المؤلفون: Emanuela Teveroni, Anna Rita Bizzarri, Ilaria Moscetti, Salvatore Cannistraro, Fabiola Moretti

المصدر: International journal of nanomedicine (Online) 11 (2016): 4221–4229. doi:10.2147/IJN.S114705
info:cnr-pdr/source/autori:Moscetti, Ilaria; Teveroni, Emanuela; Moretti, Fabiola; Bizzarri, Anna Rita; Cannistraro, Salvatore/titolo:MDM2-MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance/doi:10.2147%2FIJN.S114705/rivista:International journal of nanomedicine (Online)/anno:2016/pagina_da:4221/pagina_a:4229/intervallo_pagine:4221–4229/volume:11
International Journal of Nanomedicine

مصطلحات موضوعية: 0301 basic medicine, Kinetics, atomic force spectroscopy, Biophysics, Pharmaceutical Science, Cell Cycle Proteins, Bioengineering, Nanotechnology, Plasma protein binding, Microscopy, Atomic Force, Kinetic energy, Biomaterials, MDM4, 03 medical and health sciences, MDM2, International Journal of Nanomedicine, Proto-Oncogene Proteins, Drug Discovery, Humans, Surface plasmon resonance, Original Research, Range (particle radiation), Chemistry, Spectrum Analysis, Organic Chemistry, Force spectroscopy, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, General Medicine, Characterization (materials science), Dissociation constant, Immobilized Proteins, 030104 developmental biology, surface plasmon resonance, Protein Binding

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04eefce52c145b9ca2a1247ffbf5eda3Test
https://doi.org/10.2147/ijn.s114705Test

المؤلفون: Francesca Mancini, Rossella Lucà, Roberto Pellicciari, Nicola Giacchè, Marsha Pellegrino, Tiziana Bruno, Mara D'Onofrio, Ivan Arisi, Rossella Brandi, Laura Fici, Alfredo Pontecorvi, Antonio Macchiarulo, Isabella Manni, Jean-Christophe Marine, Marianna Buttarelli, Alice Coletti, Emanuela Teveroni, Fabiola Moretti, Giulia Piaggio, Fulvio Florenzano, Maurizio Fanciulli

المصدر: Cancer research (Chic. Ill.) 75 (2015): 4560–4572. doi:10.1158/0008-5472.CAN-15-0439
info:cnr-pdr/source/autori:Pellegrino, Marsha; Mancini, Francesca; Luca, Rossella; Coletti, Alice; Giacche, Nicola; Manni, Isabella; Arisi, Ivan; Florenzano, Fulvio; Teveroni, Emanuela; Buttarelli, Marianna; Fici, Laura; Brandi, Rossella; Bruno, Tiziana; Fanciulli, Maurizio; D'Onofrio, Mara; Piaggio, Giulia; Pellicciari, Roberto; Pontecorvi, Alfredo; Marine, Jean Christophe; Macchiarulo, Antonio; Moretti, Fabiola/titolo:Targeting the MDM2%2FMDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy/doi:10.1158%2F0008-5472.CAN-15-0439/rivista:Cancer research (Chic. Ill.)/anno:2015/pagina_da:4560/pagina_a:4572/intervallo_pagine:4560–4572/volume:75

مصطلحات موضوعية: p53, mdm2, Male, Cancer Research, Mice, Nude, Mutagenesis (molecular biology technique), Apoptosis, Cell Cycle Proteins, Peptide, Plasma protein binding, Mice, Proto-Oncogene Proteins c-mdm2, Ubiquitin, Cell Line, Tumor, Neoplasms, Proto-Oncogene Proteins, Animals, Humans, Molecular Targeted Therapy, Nuclear protein, Mice, Knockout, chemistry.chemical_classification, biology, target therapy, Ubiquitination, Nuclear Proteins, Settore MED/13 - ENDOCRINOLOGIA, HCT116 Cells, Cell biology, Oxidative Stress, Oncology, chemistry, MCF-7 Cells, biology.protein, Cancer research, Mdm2, Tumor Suppressor Protein p53, Peptides, Reactive Oxygen Species, Function (biology), Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5394eea26cda0ad1c3bfa4f2ebcfabTest
https://doi.org/10.1158/0008-5472.can-15-0439Test

المؤلفون: Emilia Luca, Rossella Lucà, Riccardo Masetti, Silvia Soddu, S. Xiong, G. Lozano, Alfredo Pontecorvi, Luisa Pieroni, Valentina Monteleone, Francesca Mancini, Fabiola Moretti, Andrea Urbani, Laura Fici

المصدر: Oncogene (Basingstoke, Online) 35 (2016): 228–240. doi:10.1038/onc.2015.76
info:cnr-pdr/source/autori:Mancini F, Pieroni L, Monteleone V, Lucà R, Fici L, Luca L, Urbani A, Xiong S, Soddu S, Masetti R, Lozano G, Pontecorvi A, Moretti F./titolo:MDM4%2FHIPK2%2Fp53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response/doi:10.1038%2Fonc.2015.76/rivista:Oncogene (Basingstoke, Online)/anno:2016/pagina_da:228/pagina_a:240/intervallo_pagine:228–240/volume:35
Oncogene

مصطلحات موضوعية: 0301 basic medicine, p53, Cancer Research, Cytoplasm, MDMX, DNA damage, Ubiquitin-Protein Ligases, Molecular Sequence Data, Cell Cycle Proteins, Mice, Transgenic, HIPK2, Protein Serine-Threonine Kinases, 03 medical and health sciences, MDM4, CELL-CYCLE ARREST, Downregulation and upregulation, Proto-Oncogene Proteins, Genetics, Serine, Animals, Humans, Nuclear protein, Molecular Biology, Psychological repression, Settore BIO/10 - BIOCHIMICA, biology, Base Sequence, INTERACTING PROTEIN KINASE-2, Kinase, apoptosis, Nuclear Proteins, Epithelial Cells, Settore MED/13 - ENDOCRINOLOGIA, Fibroblasts, HCT116 Cells, Molecular biology, Mice, Inbred C57BL, 030104 developmental biology, Ser46, biology.protein, Mdm2, Phosphorylation, Original Article, Female, Tumor Suppressor Protein p53, Carrier Proteins, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa886410acf884c1204be867c8841783Test
http://hdl.handle.net/10807/94151Test

المؤلفون: Rossella Lucà, Alfredo Pontecorvi, Fabiola Moretti, Germana Ciolli, Marsha Pellegrino, Emanuela Teveroni

مصطلحات موضوعية: 0301 basic medicine, MDMX, Peptidomimetic, Antineoplastic Agents, Cell Cycle Proteins, Computational biology, Pharmacology, Biology, P53 mdm2, anticancer peptide, Patents as Topic, 03 medical and health sciences, MDM4, therapy-resistance, 0302 clinical medicine, MDM2, Neoplasms, Proto-Oncogene Proteins, Drug Discovery, Animals, Humans, p53 reactivation therapy, Treatment resistance, Drug Discovery3003 Pharmaceutical Science, dual-inhibitor, Nuclear Proteins, P53 Tumor Suppressor, Proto-Oncogene Proteins c-mdm2, Settore MED/13 - ENDOCRINOLOGIA, General Medicine, Small molecule, 030104 developmental biology, Reduced toxicity, 030220 oncology & carcinogenesis, Drug Design, Peptidomimetics, Tumor Suppressor Protein p53, Peptides, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7d0f066f84488c188276bc31097a7eTest
http://hdl.handle.net/10807/91872Test

المؤلفون: Francesca Mancini, Fabiola Moretti

المصدر: Ovarian Cancer-Basic Science Perspective

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Mutation, biology, Serous carcinoma, medicine.disease_cause, medicine.disease, Molecular oncology, Hedgehog signaling pathway, Internal medicine, Ovarian carcinoma, Cancer research, medicine, biology.protein, Mdm2, Ovarian cancer, Gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2163f710b546b81a6d768c239c734846Test
https://doi.org/10.5772/28765Test

المؤلفون: Olimpia Monti, Marianna Buttarelli, Fabiola Moretti, Katia Scotlandi, Giusy Di Conza, Francesca Mancini, Alfredo Pontecorvi, Marsha Pellegrino

مصطلحات موضوعية: Cancer Research, Cell, Down-Regulation, Antineoplastic Agents, Apoptosis, Bone Neoplasms, Context (language use), Sarcoma, Ewing, Receptor, IGF Type 1, EWING SARCOMA, Downregulation and upregulation, Growth factor receptor, Cell Line, Tumor, medicine, Humans, Furans, Cell Proliferation, biology, Cell growth, Proto-Oncogene Proteins c-mdm2, Settore MED/13 - ENDOCRINOLOGIA, medicine.disease, medicine.anatomical_structure, Oncology, Cell culture, Immunology, Cancer research, biology.protein, Mdm2, Sarcoma, Tumor Suppressor Protein p53

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e020e01960864e60bfa847ca01dc94c4Test
http://hdl.handle.net/10807/22550Test

المؤلفون: Alfredo Pontecorvi, Francesco Trimarchi, Marianna Buttarelli, Francesca Mancini, Fabiola Moretti, Giusy Di Conza

المصدر: Cell cycle (Georget. Tex.) 11 (2012): 749–760.
info:cnr-pdr/source/autori:Giusy Di Conza 1,2; Francesca Mancini 1,3; Marianna Buttarelli 1; Alfredo Pontecorvi 3; Francesco Trimarchi 2; Fabiola Moretti 1/titolo:MDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage/doi:/rivista:Cell cycle (Georget. Tex.)/anno:2012/pagina_da:749/pagina_a:760/intervallo_pagine:749–760/volume:11

مصطلحات موضوعية: Conformational change, MDMX, mdm4, DNA damage, Ubiquitin-Protein Ligases, Regulator, Cell Line, Mice, Proto-Oncogene Proteins, Genetic model, Animals, Humans, Immunoprecipitation, Molecular Biology, Cells, Cultured, biology, Protein Stability, Reverse Transcriptase Polymerase Chain Reaction, Proto-Oncogene Proteins c-mdm2, Settore MED/13 - ENDOCRINOLOGIA, Cell Biology, Ubiquitin ligase, Cell biology, Proteasome, Biochemistry, biology.protein, Mdm2, Tumor Suppressor Protein p53, DNA Damage, Protein Binding, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0398ef48e1fcac24b3ce80b2446a04b1Test
http://hdl.handle.net/10807/12478Test

المؤلفون: Fabiola Moretti

المصدر: Molecular & Cellular Oncology 3 (2016): e1066923. doi:10.1080/23723556.2015.1066923
info:cnr-pdr/source/autori:Fabiola Moretti/titolo:Novel insights about the MDM2%2FMDM4 heterodimer/doi:10.1080%2F23723556.2015.1066923/rivista:Molecular & Cellular Oncology/anno:2016/pagina_da:e1066923/pagina_a:/intervallo_pagine:e1066923/volume:3

مصطلحات موضوعية: p53, 0301 basic medicine, Cancer Research, MDMX, DNA damage, Apoptosis, Biology, Molecular biology, Cell biology, MDM4, 03 medical and health sciences, DDB1, 030104 developmental biology, MDM2, heterodimer, Transcriptional repression, biology.protein, Molecular Medicine, Mdm2, Phosphorylation, Protein kinase A, Author's View

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647d746d9b18a084a4621ec651aaba11Test
https://doi.org/10.1080/23723556.2015.1066923Test