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1دورية أكاديمية
المؤلفون: Rukhlenko, Oleksii S., Khorsand, Fahimeh, Krstic, Aleksandar, Rozanc, Jan, Alexopoulos, Leonidas G., Rauch, Nora, Erickson, Keesha E., Hlavacek, William S., Posner, Richard G., Gómez-Coca, Silvia, Rosta, Edina, Fitzgibbon, Cheree, Matallanas, David, Rauch, Jens, Kolch, Walter, Kholodenko, Boris N.
المصدر: Rukhlenko , O S , Khorsand , F , Krstic , A , Rozanc , J , Alexopoulos , L G , Rauch , N , Erickson , K E , Hlavacek , W S , Posner , R G , Gómez-Coca , S , Rosta , E , Fitzgibbon , C , Matallanas , D , Rauch , J , Kolch , W & Kholodenko , B N 2018 , ' Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling ' , Cell Systems . https://doi.org/10.1016/j.cels.2018.06.002Test
مصطلحات موضوعية: RAF inhibitors, drug resistance, mathematical modeling, MAPK pathway, oncogenic RAS, drug synergy, RAF dimerization, conformational transitions of the DFG motif and αC helix
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.cels.2018.06.002Test
https://kclpure.kcl.ac.uk/portal/en/publications/d98610c5-93c1-4665-bb82-ec0c15fb5cc6Test
https://kclpure.kcl.ac.uk/ws/files/100137399/CELL_SYSTEMS_D_17_00367_R1.pdfTest -
2دورية أكاديمية
المؤلفون: Rukhlenko, Oleksii S., Khorsand, Fahimeh, Krstic, Aleksandar, Rozanc, Jan, Alexopoulos, Leonidas G., Rauch, Nora, Erickson, Keesha E., Hlavacek, William S., Posner, Richard G., Gómez-Coca, Silvia, Rosta, Edina, Fitzgibbon, Cheree, Matallanas, David, Rauch, Jens, Kolch, Walter, Kholodenko, Boris N.
المصدر: Rukhlenko , O S , Khorsand , F , Krstic , A , Rozanc , J , Alexopoulos , L G , Rauch , N , Erickson , K E , Hlavacek , W S , Posner , R G , Gómez-Coca , S , Rosta , E , Fitzgibbon , C , Matallanas , D , Rauch , J , Kolch , W & Kholodenko , B N 2018 , ' Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling ' , Cell Systems . https://doi.org/10.1016/j.cels.2018.06.002Test
مصطلحات موضوعية: RAF inhibitors, drug resistance, mathematical modeling, MAPK pathway, oncogenic RAS, drug synergy, RAF dimerization, conformational transitions of the DFG motif and αC helix
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.cels.2018.06.002Test
https://kclpure.kcl.ac.uk/portal/en/publications/dissecting-raf-inhibitor-resistance-by-structurebased-modeling-reveals-ways-to-overcome-oncogenic-ras-signalingTest(d98610c5-93c1-4665-bb82-ec0c15fb5cc6).html
https://kclpure.kcl.ac.uk/ws/files/100137399/CELL_SYSTEMS_D_17_00367_R1.pdfTest -
3دورية أكاديمية
المؤلفون: Rukhlenko, Oleksii S., Khorsand, Fahimeh, Krstic, Aleksandar, Rauch, Nora, Fitzgibbon, Cheree, Matallanas, David, Rauch, Jens, Kolch, Walter, Kholodenko, Boris N.
مصطلحات موضوعية: RAF inhibitors, Drug resistance, Mathematical modeling, MAPK pathway, Oncogenic RAS, Drug synergy, RAF dimerization, Conformational transitions of the DFG motif and αC helix
وصف الملف: Print-Electronic
العلاقة: Cell Systems; http://hdl.handle.net/10197/10852Test; 161; 179.e14; 750688 — SAMNets; SFI - 14/IA/2395; Mel-Plex - 642295; SmartNanoTox - 686098; NanoCommons - 731032; NIH/NIGMS - R01GM111510