المؤلفون: de Frutos, Sergio, Luengo, Alicia, García-Jérez, Andrea, Hatem-Vaquero, Marco, Griera, Mercedes, O'Valle, Francisco, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura

مصطلحات موضوعية: Chronic renal disease, Epithelial-to-mesenchymal transition, Fibrosis, Inflammation, Integrin-linked kinase, Tubulointerstitial damage, Actins, Adenine, Animals, Cadherins, Creatinine, Diet, Disease Models, Animal, Extracellular Matrix, Gene Expression Regulation, Gene Knockdown Techniques, Humans, Kidney Tubules, Male, Mice, Inbred C57BL, Transgenic, Protein Serine-Threonine Kinases, Renal Insufficiency, Chronic, Signal Transduction, Snail Family Transcription Factors, Transforming Growth Factor beta1, Urea

العلاقة: http://hdl.handle.net/10668/13525Test; https://doi.org/10.1016/j.bbadis.2019.01.024Test

الإتاحة: https://doi.org/10.1016/j.bbadis.2019.01.024Test
http://hdl.handle.net/10668/13525Test

المؤلفون: Zulong Sheng, Gaoliang Yan, Zhongpu Chen, Xiaodong Pan, Chengchun Tang, Renhua Sun

المصدر: Drug Design, Development and Therapy

مصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, Hypertension, Pulmonary, Myocytes, Smooth Muscle, Down-Regulation, Pharmaceutical Science, Protein Serine-Threonine Kinases, Pulmonary Artery, Heterogeneous-Nuclear Ribonucleoproteins, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Western blot, polypyrimidine tract-binding protein 1, pulmonary hypertension, Drug Discovery, Gene expression, medicine, Animals, Integrin-linked kinase, Original Research, Pharmacology, Gene knockdown, integrin-linked kinase, Drug Design, Development and Therapy, medicine.diagnostic_test, biology, Chemistry, Kinase, Hypoxia (medical), medicine.disease, Phenotype, Pulmonary hypertension, Cell Hypoxia, Rats, Cell biology, 030104 developmental biology, Gene Expression Regulation, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, biology.protein, medicine.symptom, pulmonary artery smooth muscle cells, Polypyrimidine Tract-Binding Protein

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef47584d32b5b7486301657f9d8c98e2Test
https://www.dovepress.com/ptbp1-targets-ilk-to-regulate-the-hypoxia-induced-phenotypic-transform-peer-reviewed-fulltext-article-DDDTTest

المساهمون: Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Moleküler Biyoloji ve Genetik Bölümü., orcid:0000-0002-1459-5485, Uz, Elif, 13807893000

مصطلحات موضوعية: Genetics & heredity, Integrin-linked kinase, Craniofacial region, Sequencing data, Cell-migration, Angiogenesis, Mechanism, Complex, Lesions, Growth, Bone, Adaptor proteins, signal transducing, Adult, Alleles, Animals, Bone and bones, Cell movement, Cytoskeletal proteins, Evolution, molecular, Female, Homozygote, Humans, Male, Mutation, Phenotype, Phylogeny, Rac GTP-binding proteins, Rac1 GTP-binding protein

وصف الملف: application/pdf

العلاقة: 108S420; K030-T439; 2011K120020; Makale - Uluslararası Hakemli Dergi; American Journal of Human Genetics; Yurt içi; Yurt dışı; Sanayi; Çetinkaya, A. vd. (2016). "Loss-of-function mutations in ELMO2 cause intraosseous vascular malformation by impeding RAC1 signaling". American Journal of Human Genetics, 99(2), 299-317.; https://doi.org/10.1016/j.ajhg.2016.06.008Test; https://www.sciencedirect.com/science/article/pii/S0002929716302105Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974086Test/; http://hdl.handle.net/11452/29550Test; 000381617200004; 2-s2.0-84979752469; 299; 317; 99

الإتاحة: https://doi.org/10.1016/j.ajhg.2016.06.008Test
http://hdl.handle.net/11452/29550Test
https://www.sciencedirect.com/science/article/pii/S0002929716302105Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974086Test/

المؤلفون: Haoliang Xue, Shuo Wu, Yiduo Zhou, Baixin Shen, Jie Gao, Liucheng Ding, Yi Huang, Yunpeng Shao, Zhongqing Wei

المصدر: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Stem Cell Research & Therapy

مصطلحات موضوعية: CD31, Male, Vascular Endothelial Growth Factor A, Angiogenesis, Basic fibroblast growth factor, Proliferation, Medicine (miscellaneous), Bone Marrow Cells, Protein Serine-Threonine Kinases, Mesenchymal Stem Cell Transplantation, Biochemistry, Genetics and Molecular Biology (miscellaneous), Bone marrow-derived mesenchymal stem cells, Streptozocin, Diabetes Mellitus, Experimental, Andrology, Rats, Sprague-Dawley, lcsh:Biochemistry, chemistry.chemical_compound, Bone Marrow, Antiapoptosis, Medicine, Animals, Humans, lcsh:QD415-436, Integrin-linked kinase, lcsh:R5-920, Glycogen Synthase Kinase 3 beta, business.industry, Research, Mesenchymal stem cell, Mesenchymal Stem Cells, Cell Biology, Streptozotocin, Rats, Vascular endothelial growth factor, Endothelial stem cell, medicine.anatomical_structure, chemistry, Molecular Medicine, Bone marrow, Diabetic cystopathy, business, lcsh:Medicine (General), medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ae9c134ea107c51f4cfb06af5d2651Test
http://link.springer.com/article/10.1186/s13287-020-01795-4Test

المؤلفون: Dezhong Yang, Ping Zhou, Xin Jiang, Wei Eric Wang, Yuqiang Fang, Rongchuan Yue, Xiaoli Yang

المصدر: Journal of Cardiovascular Translational Research

مصطلحات موضوعية: Male, 0301 basic medicine, Pharmaceutical Science, Connexin, 030204 cardiovascular system & hematology, Pharmacology, Rats, Sprague-Dawley, 0302 clinical medicine, Heart Rate, Akt Inhibitor MK2206, Myocytes, Cardiac, Phosphorylation, Integrin-linked kinase, Genetics (clinical), Ventricular Remodeling, biology, Kinase, Ventricular Fibrillation, embryonic structures, Ventricular arrhythmia, cardiovascular system, Molecular Medicine, Original Article, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents, Signal Transduction, Ischemia, Enzyme Activators, Myocardial Reperfusion Injury, Protein Serine-Threonine Kinases, 03 medical and health sciences, Genetics, medicine, Animals, cardiovascular diseases, Ventricular remodeling, Protein kinase B, business.industry, Isolated Heart Preparation, medicine.disease, Enzyme Activation, Disease Models, Animal, Ischemia reperfusion, 030104 developmental biology, Connexin 43, Tachycardia, Ventricular, biology.protein, business, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509a436583756fe3ded90bcbd4f6c2b6Test
https://doi.org/10.1007/s12265-020-09979-2Test

المؤلفون: Zhongjian Cheng, Maria Cimini, Chunlin Wang, Venkata Naga Srikanth Garikipati, Cindy Benedict, Rajika Roy, Yujia Yue, Grace Huang, Raj Kishore, May Truongcao, Walter J. Koch

المصدر: Circ Res

مصطلحات موضوعية: Male, 0301 basic medicine, Physiology, Myocardial Infarction, Inflammation, Protein Serine-Threonine Kinases, 030204 cardiovascular system & hematology, Exosomes, Systemic inflammation, Exosome, Endothelial progenitor cell, Ventricular Function, Left, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Integrin-linked kinase, Cells, Cultured, Endothelial Progenitor Cells, Wound Healing, biology, Tumor Necrosis Factor-alpha, Chemistry, Myocardium, NF-kappa B, Microvesicles, Interleukin-10, Cell biology, Mice, Inbred C57BL, Interleukin 10, 030104 developmental biology, embryonic structures, cardiovascular system, biology.protein, Stem cell, medicine.symptom, Cardiology and Cardiovascular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b20b9c07ea0d0c16f4e4261fe87d36dTest
https://doi.org/10.1161/circresaha.119.315829Test

المؤلفون: Nada Bulus, Charles R. Sanders, Ambra Pozzi, Glenda Mernaugh, Anika Böttcher, Xinyu Dong, Reinhard Fässler, Roy Zent, Kyle L. Brown

المصدر: Journal of Biological Chemistry
The Journal of Biological Chemistry
J. Biol. Chem. 296:100361 (2021)

مصطلحات موضوعية: IPP, ILK–pinch–parvin, Male, CD, collecting duct, Kidney development, Kidney, Cell morphology, Biochemistry, Mice, 0302 clinical medicine, Mice, Knockout, 0303 health sciences, biology, medicine.diagnostic_test, Chemistry, Microfilament Proteins, PBS, paxillin-binding site, LIM Domain Proteins, MD, molecular dynamics, ILK, integrin-linked kinase, Cell biology, Pleckstrin homology domain, embryonic structures, Female, Research Article, PH, pleckstrin homology, DMEM, Dulbecco's minimal essential media, Molecular Dynamics Simulation, Protein Serine-Threonine Kinases, Cell Line, 03 medical and health sciences, Protein Domains, Western blot, Cell Adhesion, medicine, Animals, Integrin-linked kinase, Cell adhesion, Molecular Biology, Adaptor Proteins, Signal Transducing, 030304 developmental biology, cell culture, Focal Adhesions, western blot, molecular modeling, Membrane Proteins, PC, principal component, Cell Biology, molecular dynamics, Mice, Inbred C57BL, Cell culture, biology.protein, Paxillin, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad61ae4ef7134c8112c643b4b35e5fccTest

المؤلفون: Kee-Pyo Kim, Wolfgang Berger, Ralf H. Adams, Kenichi Kanai, Hongryeol Park, Lea Ambühl, Hiroyuki Yamamoto, Harald J. Junge, Alessia Fraccaroli, Inga Schmidt, Lucas Mohn, Eloi Montanez, Silke Feil

المساهمون: University of Zurich, Adams, Ralf H

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, 10 (1)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Integrins, Angiogenesis, Familial Exudative Vitreoretinopathies, General Physics and Astronomy, Neovascularization, 11124 Institute of Medical Molecular Genetics, Mice, chemistry.chemical_compound, 0302 clinical medicine, Protein kinases, Blood-Retinal Barrier, lcsh:Science, Vascular diseases, Wnt Signaling Pathway, Multidisciplinary, Kinase, Microfilament Proteins, Wnt signaling pathway, 3100 General Physics and Astronomy, Metabolisme, Retinal diseases, 3. Good health, Cell biology, Phenotype, Malalties de la retina, 030220 oncology & carcinogenesis, embryonic structures, Female, medicine.symptom, Cèl·lules, Cells, Science, Neovascularization, Physiologic, 610 Medicine & health, 1600 General Chemistry, Protein Serine-Threonine Kinases, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Gene product, 10127 Institute of Evolutionary Biology and Environmental Studies, 03 medical and health sciences, 1300 General Biochemistry, Genetics and Molecular Biology, Human Umbilical Vein Endothelial Cells, medicine, Genetics, Animals, Humans, Integrin-linked kinase, Endothelial Cells, Retinal Vessels, Retinal, General Chemistry, medicine.disease, Proteïnes quinases, 030104 developmental biology, Metabolism, chemistry, biology.protein, Familial exudative vitreoretinopathy, 570 Life sciences, biology, lcsh:Q, Genètica

وصف الملف: application/pdf; application/application/pdf; 41467_2019_Article_13220.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cafe2130107c5d777f0d43c09e464cTest
http://link.springer.com/article/10.1038/s41467-019-13220-3Test

المؤلفون: Li Kang, Rory J. McCrimmon, Chandani K. Hennayake, Chenshi Lin, David H. Wasserman, Michael L.J. Ashford, Annie Hasib, Aimée R. Bugler-Lamb, Xiong Weng, Roland H Stimson

المصدر: Bugler-Lamb, A R, Hasib, A, Weng, X, Hennayake, C K, Lin, C, McCrimmon, R J, Stimson, R H, Ashford, M L J, Wasserman, D H & Kang, L 2021, ' Adipocyte Integrin-Linked Kinase Plays a Key Role in the Development of Diet-Induced Adipose Insulin Resistance in Male Mice ', Molecular Metabolism . https://doi.org/10.1016/j.molmet.2021.101197Test
Molecular Metabolism
Molecular Metabolism, Vol 49, Iss, Pp 101197-(2021)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, medicine.medical_treatment, Glucose uptake, Adipose Tissue, White, Lipolysis, Adipose tissue, 030209 endocrinology & metabolism, Intra-Abdominal Fat, Protein Serine-Threonine Kinases, Diet, High-Fat, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Insulin resistance, Downregulation and upregulation, Adipose Tissue, Brown, Internal medicine, Adipocyte, 3T3-L1 Cells, medicine, Adipocytes, Animals, Insulin, Integrin-linked kinase, Insulin clamp, Molecular Biology, biology, Cell Biology, Extracellular matrix, medicine.disease, RC31-1245, Obesity, Morbid, 030104 developmental biology, Endocrinology, Glucose, chemistry, Adipogenesis, biology.protein, Glucose Clamp Technique, Original Article, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2220c550f1ea5561ee9bcd4e29b8c6aTest
https://hdl.handle.net/20.500.11820/ac25f46a-e6be-44e7-9b61-148a81efc8d3Test

المؤلفون: Tatjana Williams, Daniel Liedtke, Henry J. Duff, Nicole M. Munsie, Jan M. Friedman, Saman Rezazadeh, William T. Gibson, Brenda Gerull, Raechel A. Ferrier, Steven J.M. Jones, Yaoqing Shen, Amy L. Stiegler, Titus J. Boggon, Andreas Brodehl, Tracey Oh, Sarah J. Childs

المصدر: Transl Res

مصطلحات موضوعية: Male, 0301 basic medicine, Adolescent, Mutant, Mutation, Missense, Cardiomyopathy, Protein Serine-Threonine Kinases, Biology, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Exome Sequencing, medicine, Animals, Humans, Missense mutation, Integrin-linked kinase, Amino Acid Sequence, Zebrafish, Exome sequencing, Sequence Homology, Amino Acid, Biochemistry (medical), Public Health, Environmental and Occupational Health, Arrhythmias, Cardiac, Dilated cardiomyopathy, General Medicine, medicine.disease, Actin cytoskeleton, Pedigree, Rats, 3. Good health, Cell biology, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, embryonic structures, biology.protein, Female, Ankyrin repeat, Cardiomyopathies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd22c63ae5c28028a3c33dcbc4718c08Test
https://doi.org/10.1016/j.trsl.2019.02.004Test