المؤلفون: Simona Casini, Vincent Portero, Gerard A Marchal, Carol Ann Remme, Joris R. de Groot, Fransisca A. Nariswari, Kaomei Guan, Antoine H.G. Driessen, Marieke W. Veldkamp, Arie O. Verkerk, Makiri Kawasaki, Nicoline W.E. van den Berg, Isabella Mengarelli

المساهمون: Cardiology, ACS - Heart failure & arrhythmias, Graduate School, Cardiothoracic Surgery, ACS - Pulmonary hypertension & thrombosis, Medical Biology, ACS - Amsterdam Cardiovascular Sciences, APH - Methodology

المصدر: Cardiovascular Drugs and Therapy
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, 33(6), 649-660. Kluwer Academic Publishers

مصطلحات موضوعية: Male, 0301 basic medicine, Action Potentials, SCN10A/Na 1.8, 030204 cardiovascular system & hematology, 0302 clinical medicine, Left atrial, Atrial Fibrillation, Medicine, Myocytes, Cardiac, Pharmacology (medical), health care economics and organizations, Cardiomyocytes, Voltage-Gated Sodium Channel Blockers, Membrane potential, Sodium channel, Cardiac electrophysiology, General Medicine, cardiovascular system, Cardiology, SCN10A/Nav1.8, Action potential duration, Original Article, Rabbits, Electrophysiologic Techniques, Cardiac, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Cell type, Heart Ventricles, Induced Pluripotent Stem Cells, Cell Line, Sodium current, NAV1.8 Voltage-Gated Sodium Channel, 03 medical and health sciences, Species Specificity, health services administration, Late sodium current, Internal medicine, Animals, Humans, Atrial Appendage, Heart Atria, Pharmacology, hiPSC-CMs, business.industry, Atrial tissue, Kinetics, 030104 developmental biology, NAV1, business, Patch-clamp

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b4ef2ce4fb577a5fa2c0e1f680be0cTest
https://doi.org/10.1007/s10557-019-06925-6Test

المؤلفون: Vincent Portero, Sridharan Rajamani, Maaike Hoekstra, Simona Casini, Luiz Belardinelli, Arthur A.M. Wilde, Arie O. Verkerk, Connie R. Bezzina, Marieke W. Veldkamp, Isabella Mengarelli, Carol Ann Remme

المساهمون: Cardiology, Graduate School, ACS - Amsterdam Cardiovascular Sciences, Medical Biology, APH - Methodology, ACS - Heart failure & arrhythmias

المصدر: Cardiovascular research, 113(7), 829-838. Oxford University Press

مصطلحات موضوعية: 0301 basic medicine, Epicardial Mapping, Male, Patch-Clamp Techniques, Physiology, Pyridines, Sodium, Induced Pluripotent Stem Cells, chemistry.chemical_element, Action Potentials, Mice, Transgenic, 030204 cardiovascular system & hematology, Pharmacology, Nerve conduction velocity, Cell Line, NAV1.5 Voltage-Gated Sodium Channel, 03 medical and health sciences, 0302 clinical medicine, Heart Rate, Physiology (medical), Cardiac conduction, Repolarization, Myocyte, Animals, Genetic Predisposition to Disease, Myocytes, Cardiac, cardiovascular diseases, Voltage-Gated Sodium Channel Blockers, Sodium channel, Wild type, Isolated Heart Preparation, Triazoles, Kinetics, Long QT Syndrome, 030104 developmental biology, Phenotype, chemistry, Mutation, cardiovascular system, Female, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6f2642f26ec672b7e7a43ff709af2bTest
https://doi.org/10.1093/cvr/cvx077Test

المؤلفون: Jade Violleau, Stefan Kääb, Susan Bartkowiak, Richard Redon, Antoine Leenhardt, Hanno L. Tan, Jean-Baptiste Gourraud, Peter Weeke, Rachel Bastiaenen, Rianne Wolswinkel, Federica Dagradi, Vincent M. Christoffels, Jacob Tfelt-Hansen, Jean-Jacques Schott, Hervé Le Marec, Manfred Gessler, Françoise Gros, Pascale Guicheney, Julien Barc, Arthur A.M. Wilde, Simon Lecointe, Akihiko Nogami, Tohru Minamino, Sven Zumhagen, Margherita Torchio, Elijah R. Behr, Rainer Schimpf, Carol Ann Remme, Florence Kyndt, Lia Crotti, Yuka Mizusawa, Morten S. Olesen, Vincent Probst, Naoto Endo, Naomasa Makita, Eric Charpentier, Philippe Froguel, Arie O. Verkerk, Minoru Horie, Takeshi Aiba, Christian Dina, Peter J. Schwartz, Kanae Hasegawa, Floriane Simonet, Véronique Fressart, Seiko Ohno, Cornelia Wiese, Eric Schulze-Bahr, Stéphane Bézieau, Hiroshi Watanabe, Vincent Portero, Wataru Shimizu, Beverley Balkau, Martin Borggrefe, Britt M. Beckmann, Charles Antzelevitch, Bas J. Boukens, Dan M. Roden, Pierre Lindenbaum, Aurore Despres, David Weber, Olivier Lantieri, Connie R. Bezzina, Stéphanie Chatel, Ruben Coronel

المساهمون: ACS - Amsterdam Cardiovascular Sciences, Cardiology, Medical Biology, Other departments, ARD - Amsterdam Reproduction and Development, Bezzina, C, Barc, J, Mizusawa, Y, Remme, C, Gourraud, J, Simonet, F, Verkerk, A, Schwartz, P, Crotti, L, Dagradi, F, Guicheney, P, Fressart, V, Leenhardt, A, Antzelevitch, C, Bartkowiak, S, Borggrefe, M, Schimpf, R, Schulze-Bahr, E, Zumhagen, S, Behr, E, Bastiaenen, R, Tfelt-Hansen, J, Olesen, M, Kääb, S, Beckmann, B, Weeke, P, Watanabe, H, Endo, N, Minamino, T, Horie, M, Ohno, S, Hasegawa, K, Makita, N, Nogami, A, Shimizu, W, Aiba, T, Froguel, P, Balkau, B, Lantieri, O, Torchio, M, Wiese, C, Weber, D, Wolswinkel, R, Coronel, R, Boukens, B, Bézieau, S, Charpentier, E, Chatel, S, Despres, A, Gros, F, Kyndt, F, Lecointe, S, Lindenbaum, P, Portero, V, Violleau, J, Gessler, M, Tan, H, Roden, D, Christoffels, V, Le Marec, H, Wilde, A, Probst, V, Schott, J, Dina, C, Redon, R

المصدر: Nature genetics, 45(9), 1044-1049. Nature Publishing Group

مصطلحات موضوعية: Male, Qrs Duration, Bioinformatics, Sodium Channels, NAV1.5 Voltage-Gated Sodium Channel, Sudden cardiac death, Genome-Wide Association, Mice, Atrial Gene-Expression, Basic Helix-Loop-Helix Transcription Factors, Odds Ratio, Brugada Syndrome, Brugada syndrome, Mice, Knockout, St-Segment Elevation, SECS-S/01 - STATISTICA, cardiovascular system, Cardiology, Chromosomes, Human, Pair 6, Female, Chromosomes, Human, Pair 3, medicine.medical_specialty, Bundle-Branch Block, BIO/18 - GENETICA, Locus (genetics), Biology, Polymorphism, Single Nucleotide, Article, NAV1.8 Voltage-Gated Sodium Channel, Internal medicine, Genetic variation, Cardiac conduction, Genetics, medicine, Animals, Humans, Genetic Predisposition to Disease, cardiovascular diseases, HEY2, Alleles, Heart-Rate, Genetic Variation, Cardiac arrhythmia, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, medicine.disease, Qt Interval Duration, Repressor Proteins, Ventricular-Fibrillation, Pr Interval, Death, Sudden, Cardiac, Case-Control Studies, Conduction System, Genome-Wide Association Study, Rare disease

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8578dbbe2ed8dd464bb8685a62569057Test
https://doi.org/10.1038/ng.2712Test

المؤلفون: Gildas Loussouarn, Vincent Probst, Thomas O'Hara, Christian Dina, Carol Scott, Eléonore Moreau, Solena Le Scouarnec, Stéphanie Chatel, Stéphanie Bonnaud, Hervé Le Marec, Sophie Burel, Flavien Charpentier, Jade Violleau, Isabelle Baró, Estelle Baron, Pierre Lindenbaum, Vincent Portero, Jean-Jacques Schott, Floriane Simonet, Céline Marionneau, Philippe Mabo, Zeineb Es‐Salah‐Lamoureux, Jean-Baptiste Gourraud, Richard Redon

المساهمون: Jonchère, Laurent, Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), The Wellcome Trust Sanger Institute [Cambridge], CIC-IT Rennes, Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], Leducq Foundation [CVD-05], Fondation pour la Recherche Medicale [DEQ20140329545], Inserm, French Regional Council of Pays-de-la-Loire, Fondation Lefoulon-Delalande, Fondation pour la Recherche Medicale, Fondation Genavie, Wellcome Trust [WT098051], European Commission [NavEx-256397], unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association
Journal of the American Heart Association, 2016, 5 (6), pp.e003122. ⟨10.1161/JAHA.115.003122⟩
Journal of the American Heart Association, Wiley-Blackwell, 2016, 5 (6), pp.e003122. ⟨10.1161/JAHA.115.003122⟩

مصطلحات موضوعية: Male, 0301 basic medicine, Arrhythmias, 030204 cardiovascular system & hematology, whole exome sequencing, NAV1.5 Voltage-Gated Sodium Channel, Electrocardiography, 0302 clinical medicine, Genotype, Missense mutation, Arrhythmia and Electrophysiology, genetics, Exome sequencing, risk, Original Research, Brugada syndrome, Genetics, maps, clinical electrophysiology, potassium ion channels, potassium channels, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Pedigree, 3. Good health, Electrophysiology, modulation, Shal Potassium Channels, Potassium Channels, Voltage-Gated, Gain of Function Mutation, Cardiology, Female, abnormalities, Cardiology and Cardiovascular Medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, gene prioritization, j-wave syndromes, [SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics, Polymorphism, Single Nucleotide, Sudden death, sudden cardiac death, cardiac arrhythmia, 03 medical and health sciences, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Genetic linkage, Internal medicine, Exome Sequencing, medicine, Humans, Genetic Predisposition to Disease, cardiovascular diseases, Gene, disease, business.industry, KCNAB2/Kvβ2, mutations, medicine.disease, 030104 developmental biology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Shaker Superfamily of Potassium Channels, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3440d96795391b62f34d35fdffadddTest
https://doi.org/10.1161/jaha.115.003122Test

المؤلفون: Solena Le Scouarnec, Raluca Teusan, Stéphanie Bonnaud, Vincent Portero, Frederic Sacher, Sébastien Schmitt, Richard Redon, Jean-Baptiste Gourraud, Jade Violleau, Raphaël P. Martins, Julien Barc, Pierre Lindenbaum, Hervé Le Marec, Michel Haïssaguerre, Christian Dina, Estelle Baron, Lise Bellanger, Jean-Jacques Schott, Elodie Persyn, F. Kyndt, Philippe Mabo, Matilde Karakachoff, Vincent Probst, Stéphanie Chatel, Floriane Simonet, Laëtitia Duboscq-Bidot, Stéphane Bézieau, Xavier Daumy

المساهمون: Cardiology, unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Mathématiques Jean Leray (LMJL), Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Service de Génétique, Centre hospitalier universitaire de Nantes (CHU Nantes), Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Human molecular genetics, 24(10), 2757-2763. Oxford University Press
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 24 (10), pp.2757--2763. ⟨10.1093/hmg/ddv036⟩
Human Molecular Genetics, 2015, 24 (10), pp.2757--2763. ⟨10.1093/hmg/ddv036⟩

مصطلحات موضوعية: Adult, Male, [SDV]Life Sciences [q-bio], Population, 030204 cardiovascular system & hematology, Biology, White People, NAV1.5 Voltage-Gated Sodium Channel, Sudden cardiac death, 03 medical and health sciences, 0302 clinical medicine, Gene Frequency, Genetic variation, Genetics, medicine, Humans, Genetic Predisposition to Disease, cardiovascular diseases, education, Molecular Biology, Allele frequency, Genetic Association Studies, Genetics (clinical), Brugada Syndrome, 030304 developmental biology, Brugada syndrome, 0303 health sciences, education.field_of_study, fungi, Cardiac arrhythmia, Arrhythmias, Cardiac, Sequence Analysis, DNA, General Medicine, Middle Aged, medicine.disease, 3. Good health, Minor allele frequency, Genes, Mutation, Ventricular fibrillation, cardiovascular system, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82a7e220206ae83735e79cb61fa7449Test
https://pure.amc.nl/en/publications/testing-the-burden-of-rare-variation-in-arrhythmiasusceptibility-genes-provides-new-insights-into-molecular-diagnosis-for-brugada-syndromeTest(21b01ce8-86af-4ceb-9bff-cc9a3f3620df).html

المؤلفون: Michel Haïssaguerre, Hervé Le Marec, Solena Le Scouarnec, Frederic Sacher, Juan E. Sandoval, Nicolas Derval, Vincent Probst, Jean-Jacques Schott, Philippe Mabo, Jean-Baptiste Gourraud, Pascal Chavernac, Stéphanie Chatel, Richard Redon, Vincent Portero

المساهمون: unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Département de cardiologie, CHU Bordeaux [Bordeaux]-Hôpital Haut-Lévêque [CHU Bordeaux], CHU Bordeaux [Bordeaux], Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service de cardiologie et maladies vasculaires, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes]

المصدر: Journal of the American College of Cardiology
Journal of the American College of Cardiology, Elsevier, 2013, 61 (2), pp.164-72. ⟨10.1016/j.jacc.2012.09.040⟩

مصطلحات موضوعية: Proband, Male, Benign early repolarization, medicine.medical_treatment, Disease, 030204 cardiovascular system & hematology, early repolarization syndrome, Electrocardiography, 0302 clinical medicine, [INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing, Heart Rate, Valsalva maneuver, MESH: Syndrome, 030212 general & internal medicine, Young adult, MESH: Heart Rate, MESH: Aged, MESH: Middle Aged, medicine.diagnostic_test, Syndrome, Middle Aged, 3. Good health, Pedigree, MESH: Arrhythmias, Cardiac, familial inheritance, MESH: Young Adult, Cardiology, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Female, Cardiology and Cardiovascular Medicine, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, MESH: Valsalva Maneuver, Adult, medicine.medical_specialty, Adolescent, MESH: Pedigree, Valsalva Maneuver, 03 medical and health sciences, Young Adult, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Internal medicine, Heart rate, medicine, Humans, Aged, MESH: Adolescent, MESH: Humans, business.industry, MESH: Adult, MESH: Death, Sudden, Cardiac, Arrhythmias, Cardiac, medicine.disease, ventricular fibrillation, MESH: Male, MESH: Electrocardiography, Endocrinology, Death, Sudden, Cardiac, Ventricular fibrillation, business, MESH: Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae605239a694495fe745afed5e24df60Test
https://pubmed.ncbi.nlm.nih.gov/23273291Test

المؤلفون: Thomas J van Brakel, Guoqi Zhang, Balázs Ördög, Titus van den Heuvel, Vincent Portero, Magda S Fontes, Arti A. Ramkisoensing, Katja Zeppenfeld, Catilin Ramsey, E.C.A. Nyns, Tianyi Jin, Daniël A. Pijnappels, Cindy I. Bart, R. H. Poelma, Martin J. Schalij, Antoine A.F. de Vries

المصدر: Cardiovascular Research, 118(10), 2293-2303. OXFORD UNIV PRESS
Cardiovascular Research, 118(10)

مصطلحات موضوعية: Male, medicine.medical_specialty, Physiology, Ventricular Tachyarrhythmias, medicine.medical_treatment, Rat model, Electric Countershock, Channelrhodopsin, 030204 cardiovascular system & hematology, Optogenetics, Cardioversion, 03 medical and health sciences, 0302 clinical medicine, Channelrhodopsins, In vivo, Physiology (medical), Internal medicine, medicine, Animals, Sinus rhythm, Rats, Wistar, 030304 developmental biology, 0303 health sciences, business.industry, Remodelling, Arrhythmias, Cardiac, Ventricular tachycardias, Rats, Tachycardia, Ventricular, Cardiology, Cardiomyopathies, Cardiology and Cardiovascular Medicine, business, Ex vivo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ef2b9963bfd891968b830bba540394Test