المؤلفون: Paul J. Emmerson, David J. Hodson, Brandy M. Snider, Nicolas Nunn, Tamer Coskun, Jenna Hunter, Mehdi Boutagouga Boudjadja, Gabriella Aviello, Isabella Culotta, Minrong Ai, Simon M. Luckman, Alessia Costa, Giuseppe D'Agostino, Lourdes Valencia-Torres

المساهمون: Costa, A., Ai, M., Nunn, N., Culotta, I., Hunter, J., Boudjadja, M. B., Valencia-Torres, L., Aviello, G., Hodson, D. J., Snider, B. M., Coskun, T., Emmerson, P. J., Luckman, S. M., D'Agostino, G.

المصدر: Costa, A, Ai, M, Nunn, N, Culotta, I, Hunter, J, Boudjadja, M B, Valencia-Torres, L, Aviello, G, Hodson, D J, Snider, B M, Coskun, T, Emmerson, P J, Luckman, S M & D'Agostino, G 2021, ' Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation ', Molecular Metabolism, vol. 55, 101407 . https://doi.org/10.1016/j.molmet.2021.101407Test
Molecular Metabolism
Molecular Metabolism, Vol 55, Iss, Pp 101407-(2022)

مصطلحات موضوعية: Blood Glucose, Male, Glucagon-like peptide-1, endocrine system, Glucose-dependent insulinotropic polypeptide, media_common.quotation_subject, Appetite, Gastric Inhibitory Polypeptide, Brief Communication, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, Mice, Nucleus of the solitary tract, Glucagon-Like Peptide 1, Appetite Depressants, Medicine, Animals, Hypoglycemic Agents, Insulin, Receptor, Internal medicine, Molecular Biology, Glucagon-like peptide 1 receptor, media_common, Cholecystokinin, Neurons, business.industry, Area postrema, digestive, oral, and skin physiology, Brain, Nausea, Cell Biology, Liraglutide, Glucagon, RC31-1245, Mice, Inbred C57BL, Anorectic, Exenatide, Female, Brainstem, business, Neuroscience, hormones, hormone substitutes, and hormone antagonists

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c8f4b8195f8ad7f7f17bc35a2d9541Test
https://www.research.manchester.ac.uk/portal/en/publications/anorectic-and-aversive-effects-of-glp1-receptor-agonism-are-mediated-by-brainstem-cholecystokinin-neurons-and-modulated-by-gip-receptor-activationTest(97b025ca-ff46-4b48-a59c-edf8df09098e).html

المؤلفون: Hakan Ozben, Tamer Coskun

المساهمون: Koç University Hospital, School of Medicine, Department of Orthopedics and Traumatology

المصدر: BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-8 (2019)
BMC Musculoskeletal Disorders

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, lcsh:Diseases of the musculoskeletal system, Adolescent, Giant Cell Tumor of Tendon Sheath, Young Adult, 03 medical and health sciences, Giant-cell tumor of the tendon sheath, 0302 clinical medicine, Rheumatology, Tendon sheath, Recurrence, medicine, Humans, Orthopedics and Sports Medicine, Giant Cell Tumors, Aged, Retrospective Studies, business.industry, Standard treatment, Medicine, Orthopedics, Hand surgery, Middle Aged, medicine.disease, Neurovascular bundle, Hand, Ganglion cyst, Dissection, Risk factors, 030220 oncology & carcinogenesis, Female, Radiology, Giant cell tumor, Neoplasm Recurrence, Local, lcsh:RC925-935, business, 030217 neurology & neurosurgery, Follow-Up Studies, Research Article

وصف الملف: pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2255da99115d4f5d230d982bea466b11Test
http://link.springer.com/article/10.1186/s12891-019-2866-8Test

المؤلفون: Sander Kooijman, Zhixiong Ying, Tamer Coskun, Patrick C.N. Rensen, Mariëtte R. Boon

المصدر: Physiological Reports
Physiological Reports, 9(8). WILEY
Physiological Reports, Vol 9, Iss 8, Pp n/a-n/a (2021)

مصطلحات موضوعية: Male, Very low-density lipoprotein, Physiology, Sonication, Lipoproteins, plasma triglyceride metabolism, Fractionation, 030204 cardiovascular system & hematology, Tritium, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Physiology (medical), Glycerol, Lipolysis, QP1-981, Animals, Tissue Distribution, Carbon Radioisotopes, Triglycerides, lipoprotein metabolism, Chromatography, lipoprotein kinetics, Metabolism, Original Articles, Mice, Inbred C57BL, Cholesterol, chemistry, Adipose Tissue, Density gradient ultracentrifugation, Original Article, VLDL, 030217 neurology & neurosurgery, Triolein, Lipoprotein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdf002c4c8fdbeb34ef89b0c7e7ef2eTest
https://pubmed.ncbi.nlm.nih.gov/33945228Test

المؤلفون: Tamer Coskun, Claire H. Feetham, Giuseppe D'Agostino, Garron T. Dodd, Amy A. Worth, Frank Reimann, James D. Dunbar, Fiona M. Gribble, Simon M. Luckman, Paul J. Emmerson, Katie Tye, Emily C Beebe, Dana Sindelar, Jesline T. Alexander-Chacko, Rosemary Shoop

المساهمون: Worth, Amy A [0000-0003-2573-7140], Shoop, Rosemary [0000-0002-3617-4358], Luckman, Simon M [0000-0001-5318-5473], Apollo - University of Cambridge Repository

المصدر: Worth, A A, Shoop, R, Tye, K, Feetham, C H, D'Agostino, G, Dodd, G T, Reimann, F, Gribble, F M, Beebe, E C, Dunbar, J D, Alexander-Chacko, J T, Sindelar, D K, Coskun, T, Emmerson, P J & Luckman, S M 2020, ' The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling ', eLife, vol. 9, e55164, pp. 1-19 . https://doi.org/10.7554/eLife.55164Test
eLife, Vol 9 (2020)
eLife

مصطلحات موضوعية: 0301 basic medicine, Male, food intake, Lydia Becker Institute, medicine.medical_treatment, cisplatin, brainstem, neuroscience, Rats, Sprague-Dawley, Mice, Random Allocation, 0302 clinical medicine, rat, Biology (General), Receptor, Cholecystokinin, Neurons, education.field_of_study, GFRAL, General Neuroscience, Area postrema, General Medicine, Recombinant Proteins, Anorexia, Cytokine, Pica, Medicine, medicine.symptom, Signal transduction, Research Article, Signal Transduction, medicine.medical_specialty, Growth Differentiation Factor 15, QH301-705.5, Science, Population, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, medicine, Animals, education, mouse, General Immunology and Microbiology, CCK, Rats, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, GDF15, nervous system, Anorectic, 030217 neurology & neurosurgery, Brain Stem

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c36fee4c12ae9aa6d1944526e39affeTest

المؤلفون: Jan-Bert van Klinken, Laura G.M. Janssen, Sander Kooijman, Jari A. van der Eijk, Lisanne A. Overduin, Michel van Weeghel, Andrew G. Webb, Ko Willems van Dijk, Tamer Coskun, Jonatan R. Ruiz, Kimberly J. Nahon, Ingrid M. Jazet, Frédéric M. Vaz, Jedrzej Burakiewicz, Oleh Dzyubachyk, Hermien E. Kan, Mariëtte R. Boon, Manu P. Bilsen, Patrick C.N. Rensen, Aashley S.D. Sardjoe Mishre, Kani Botani, Borja Martinez-Tellez, Jimmy F.P. Berbée

المساهمون: Laboratory Genetic Metabolic Diseases, Laboratory for General Clinical Chemistry, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, APH - Personalized Medicine, APH - Methodology, ACS - Diabetes & metabolism

المصدر: Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Diabetes, Obesity & Metabolism
Diabetes, obesity & metabolism, 22(11), 2032-2044. Wiley-Blackwell
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Diabetes, Obesity and Metabolism, 22(11), 2032-2044. WILEY

مصطلحات موضوعية: Male, medicine.medical_specialty, South asia, Endocrinology, Diabetes and Metabolism, Metabolic disease, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Placebo, Brown adipose tissue, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Adipose Tissue, Brown, Asian People, Lipid oxidation, Internal medicine, energy expenditure, lipid metabolism, Internal Medicine, Humans, Medicine, South Asian, Resting energy expenditure, Mirabegron, Cross-Over Studies, business.industry, Lipidic metabolism, Thermogenesis, Lipid metabolism, brown adipose tissue, Original Articles, metabolic disease, mirabegron, Cold Temperature, Thiazoles, medicine.anatomical_structure, Acetanilides, Original Article, Energy expenditure, Energy Metabolism, business, Body mass index, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9bd86597fa3208fd611614e9746d05Test
https://doi.org/10.1111/dom.14120Test

المؤلفون: Patrick J. Antonellis, James W. Perfield, Brian A. Droz, Tamer Coskun, Richard Cosgrove, Tara E. Chouinard, Andrew C. Adams, Steven M. Bauer, Mark R. Wade, Libbey S. O’Farrell, Ricardo J. Samms, Joseph T. Brozinick

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 30, Iss, Pp 131-139 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, CYP7A1, Adipose tissue, Mice, Obese, FGF19, Mice, 0302 clinical medicine, Adipose Tissue, Brown, Brown adipose tissue, Uncoupling Protein 1, Mice, Knockout, Bile acid, Chemistry, Thermogenesis, Thermogenin, Mitochondria, medicine.anatomical_structure, medicine.medical_specialty, lcsh:Internal medicine, UCP1, medicine.drug_class, Adipose Tissue, White, 030209 endocrinology & metabolism, Cholesterol 7 alpha-hydroxylase, Brief Communication, Diet, High-Fat, Diabetes Mellitus, Experimental, Mitochondrial Proteins, 03 medical and health sciences, Internal medicine, medicine, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, Lipogenesis, Body Weight, BAT, Lipid metabolism, Cell Biology, Lipid Metabolism, Fibroblast Growth Factors, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolic, Insulin Resistance, Energy Metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3a672ee97f46b2f383c07d191a28e6Test
https://pubmed.ncbi.nlm.nih.gov/31767164Test

المؤلفون: Qian Liu, Ruth E. Gimeno, Jason X. Tang, Gavin C. Barnard, Xilin Liu, Yong Du, Jorge Alsina-Fernandez, Paul J. Emmerson, Avinash Muppidi, Bei B Zhang, Richard Todd Pickard, Matthew J Hamang, Bei Shan, Tamer Coskun, Pamela Jean Mitchell, Malgorzata Donata Gonciarz, Kimberly K Ballman, John H. Sloan, Xinle Wu, Xudong Mao, Lisa A Foltz, Feng Wang, Dana Sindelar, Robert W. Siegel

المصدر: Nature Medicine. 23:1215-1219

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Glial Cell Line-Derived Neurotrophic Factor Receptors, Growth Differentiation Factor 15, Immunoblotting, Biology, Real-Time Polymerase Chain Reaction, General Biochemistry, Genetics and Molecular Biology, Rats, Sprague-Dawley, Eating, Mice, 03 medical and health sciences, Estrogen-related receptor alpha, 0302 clinical medicine, Internal medicine, Weight Loss, medicine, Animals, Humans, 5-HT5A receptor, Obesity, RNA, Messenger, Receptor, Mice, Knockout, Orphan receptor, Brain, General Medicine, Surface Plasmon Resonance, Flow Cytometry, Rats, Neuron-derived orphan receptor 1, Macaca fascicularis, HEK293 Cells, 030104 developmental biology, Endocrinology, Area Postrema, ROR1, Estrogen-related receptor gamma, GDF15, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502200f39c5bdc1b589339efb20908aTest
https://doi.org/10.1038/nm.4393Test

المؤلفون: Joseph T. Brozinick, Steve Bauer, Evan M Niemeier, Thais de Castro Barbosa, Alexander V. Chibalin, Jorge Alsina-Fernandez, Julie Massart, Håkan K. R. Karlsson, Tamer Coskun, Lili Guo, Elizabeth O'Farrell, Juleen R. Zierath, Andrew Ryan, Milena Schönke, Anna Krook, Melissa L. Borg, Rebecca R. Miles, Mark R. Wade

المصدر: Diabetes. 68(7)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Blotting, Western, 030209 endocrinology & metabolism, 03 medical and health sciences, Gastrocnemius muscle, Mice, 0302 clinical medicine, Insulin resistance, Internal medicine, Internal Medicine, medicine, Myocyte, Animals, Humans, Phosphorylation, Muscle, Skeletal, Urocortins, Soleus muscle, biology, Chemistry, Insulin, Skeletal muscle, medicine.disease, Rats, Mice, Inbred C57BL, Insulin receptor, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Electroporation, Glucose, HEK293 Cells, biology.protein, Body Composition, Insulin Resistance, GLUT4, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cae7ff42babbca68b2c86cdd35ffd7Test
https://pubmed.ncbi.nlm.nih.gov/31010957Test

المؤلفون: Geerte Hoeke, Anne Reifel Miller, Patrick C.N. Rensen, Lea H. Dib, Bharat Shimpukade, Trond Ulven, Tamer Coskun, Anthony Okolo, Sander Kooijman, Maaike Schilperoort, Natarin Caengprasath, Mark Christian, Yi-Wah Chan, Aylin C. Hanyaloglu, Andrea D. van Dam, Sami Damak, Isabel M. Mol, Irina G. Shabalina

المساهمون: Biotechnology and Biological Sciences Research Council (BBSRC)

المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine, 10(3)
Schilperoort, M, van Dam, A D, Hoeke, G, Shabalina, I G, Okolo, A, Hanyaloglu, A C, Dib, L H, Mol, I M, Caengprasath, N, Chan, Y-W, Damak, S, Miller, A R, Coskun, T, Shimpukade, B, Ulven, T, Kooijman, S, Rensen, P C & Christian, M 2018, ' The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat ', EMBO Molecular Medicine, vol. 10, no. 3, e8047 . https://doi.org/10.15252/emmm.201708047Test

مصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), Ca, GPR120, Adipocytes, White, Gene Expression Regulation/drug effects, Phenylpropionates/pharmacology, QH426-470, Mitochondrion, Receptors, G-Protein-Coupled, Oxygen Consumption/drug effects, Adipose Tissue, Brown, Receptors, G-Protein-Coupled/agonists, Brown adipose tissue, lipid metabolism, Glucose/metabolism, Adipose Tissue, Brown/drug effects, Research Articles, Uncoupling Protein 1, Adiposity, Phenylpropionates, Chemistry, Cell Differentiation, 11 Medical And Health Sciences, Lipids, Mitochondria/drug effects, mitochondria, Ca2+, medicine.anatomical_structure, Adipocytes, Brown, Molecular Medicine, Adipocytes, Brown/cytology, Mitochondrial fission, Oxidation-Reduction, Research Article, Agonist, medicine.medical_specialty, medicine.drug_class, Adipose Tissue, White, Cell Respiration, Adiposity/drug effects, Carbohydrate metabolism, Models, Biological, Adipocytes, White/cytology, 03 medical and health sciences, R5-920, Oxygen Consumption, Adipose Tissue, White/drug effects, Internal medicine, Cell Respiration/drug effects, Genetics, medicine, Animals, Body Weight/drug effects, Pharmacology & Drug Discovery, Biphenyl Compounds, Body Weight, Uncoupling Protein 1/metabolism, Lipid metabolism, brown adipose tissue, 06 Biological Sciences, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolism, Glucose, Gene Expression Regulation, Cell Differentiation/drug effects, Biphenyl Compounds/pharmacology, Thermogenesis, RC

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500a414f38fbfef93af89f8a97f0493Test
http://wrap.warwick.ac.uk/97936/1/GPR120-agonist-TUG-391-promotes-Christian-2018.pdfTest

المؤلفون: Richard G. Peterson, Karen M. Zimmerman, M. Dodson Michael, Bria L. Sneed, Paul J. Emmerson, Brian A. Droz, Charles V. Jackson, Tamer Coskun

المصدر: PLoS ONE, Vol 12, Iss 6, p e0179808 (2017)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Leptin, Blood Glucose, Male, Physiology, medicine.medical_treatment, Peptide Hormones, Type 2 diabetes, Biochemistry, Fats, Eating, Mice, 0302 clinical medicine, Endocrinology, Hyperinsulinemia, Medicine and Health Sciences, Medicine, Insulin, 2. Zero hunger, Multidisciplinary, Organic Compounds, Monosaccharides, Animal Models, Lipids, 3. Good health, Chemistry, Physiological Parameters, Experimental Organism Systems, Physical Sciences, medicine.symptom, Research Article, medicine.medical_specialty, Offspring, Science, Carbohydrates, 030209 endocrinology & metabolism, Mouse Models, Research and Analysis Methods, Diet, High-Fat, 03 medical and health sciences, Insulin resistance, Model Organisms, Diabetes mellitus, Internal medicine, Animals, Obesity, Pancreas, Nutrition, Diabetic Endocrinology, business.industry, Body Weight, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, medicine.disease, Hormones, Diet, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, business, Weight gain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff96d25ea08c7654451bfe234ee4c5aTest
https://doaj.org/article/bb9f14c1cae741f99f99a57996878039Test