المؤلفون: Rivera-Torres, José, Calvo, Conrado J, Llach, Anna, Guzmán-Martínez, Gabriela, Caballero, Ricardo, González-Gómez, Cristina, Jiménez-Borreguero, Luis J, Guadix, Juan A, Osorio, Fernando G, López-Otín, Carlos, Herraiz-Martínez, Adela, Cabello, Nuria, Vallmitjana, Alex, Benítez, Raul, Gordon, Leslie B, Jalife, José, Pérez-Pomares, José M, Tamargo, Juan, Delpón, Eva, Hove-Madsen, Leif, Filgueiras-Rama, David, Andrés, Vicente

مصطلحات موضوعية: Hutchinson–Gilford progeria syndrome, calcium handling, connexin43, prelamin A, progerin, Adolescent, Adult, Animals, Arrhythmias, Cardiac, Calcium, Cardiac Conduction System Disease, Child, Preschool, Connexin 43, Female, Heart, Humans, Male, Membrane Proteins, Metalloendopeptidases, Mice, Inbred C57BL, Knockout, Myocardium, Nuclear Lamina, Progeria, Sarcoplasmic Reticulum, Young Adult

العلاقة: http://hdl.handle.net/10668/10568Test; PMC5135377; https://europepmc.org/articles/pmc5135377?pdf=renderTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135377/pdfTest

الإتاحة: https://doi.org/10.1073/pnas.1603754113Test
http://hdl.handle.net/10668/10568Test
https://europepmc.org/articles/pmc5135377?pdf=renderTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135377/pdfTest

المؤلفون: Ricardo Villa-Bellosta

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, 0301 basic medicine, 030204 cardiovascular system & hematology, Pyrophosphate, Mice, chemistry.chemical_compound, Adenosine Triphosphate, Progeria, 0302 clinical medicine, Gene Knock-In Techniques, Pyrophosphatases, RNA, Small Interfering, media_common, Multidisciplinary, integumentary system, Apyrase, Longevity, Calcinosis, Biological Sciences, Lamin Type A, Diphosphates, RNA Interference, Hutchinson Gilford Progeria Syndrome, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, media_common.quotation_subject, Myocytes, Smooth Muscle, Aortic Diseases, Mice, Transgenic, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Antigens, CD, Internal medicine, medicine, Animals, Humans, Vascular calcification, Phosphoric Diester Hydrolases, business.industry, nutritional and metabolic diseases, Alkaline Phosphatase, medicine.disease, Disease Models, Animal, 030104 developmental biology, Endocrinology, Levamisole, chemistry, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc5d2c846386409bed45f6b6a6f47f5Test
https://doi.org/10.1073/pnas.1910972116Test

المؤلفون: Villa-Bellosta, Ricardo, Rivera-Torres, Jose, Osorio, Fernando G, Acin-Perez, Rebeca, Enriquez, Jose Antonio, López-Otín, Carlos, Andres, Vicente

المساهمون: Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Progeria Research Foundation, Botín Foundation, Fundación Cajastur, Fundación ProCNIC

مصطلحات موضوعية: ATP, Hutchinson-Gilford progeria syndrome, muscle, Progerin, Pyrophosphate, Tissue-non specific alkaline phosphatase, Vascular calcification, Smooth, Adenosine Triphosphate, Alkaline Phosphatase, Animals, Aorta, Cells, Cultured, Diphosphates, Disease Models, Animal, Lamin Type A, Male, Mice, Inbred C57BL, Mutant Strains, Mitochondria, Vascular, Progeria, Treatment Outcome

العلاقة: Postprint; https://doi.org/10.1161/CIRCULATIONAHA.112.000571Test; info:eu-repo/grantAgreement/ES/SAF2010-16044; info:eu-repo/grantAgreement/ES/RD06/0014/0021; info:eu-repo/grantAgreement/ES/RD12/0042/0028; info:eu-repo/grantAgreement/ES/JCI-2011-09663; Circulation. 2013; 127(24):2442-51; http://hdl.handle.net/20.500.12105/7754Test; Circulation

الإتاحة: https://doi.org/20.500.12105/7754Test
https://doi.org/10.1161/CIRCULATIONAHA.112.000571Test
https://hdl.handle.net/20.500.12105/7754Test

المؤلفون: Yaazan Blanco, María J. Andrés-Manzano, José Jalife, Víctor Fanjul, Pilar Gonzalo, David Filgueiras-Rama, Andre Monteiro da Rocha, Vicente Andrés, J Jaime Díaz-Larrosa, Cristina González-Gómez, Alvaro Macias, Andrew Allan, Daniela Ponce-Balbuena

المساهمون: Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Progeria Research Foundation, Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España), Fundación ProCNIC, NIH - National Heart, Lung, and Blood Institute (NHLBI) (Estados Unidos)

المصدر: Cardiovascular Research

مصطلحات موضوعية: Male, Refractory Period, Electrophysiological, Physiology, Swine, Cardiac index, Action Potentials, Laminopathy, Afterdepolarization, Progerin, Progeria, Heart Rate, Tubulin, Myocytes, Cardiac, AcademicSubjects/MED00200, Cytoskeleton, Excitation Contraction Coupling, Cardiomyocytes, integumentary system, Lamin Type A, Electrophysiology, Cardiology, Swine, Miniature, Female, Electrical conduction system of the heart, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents, medicine.medical_specialty, Paclitaxel, Cardiac Electrophysiology and Arrhythmia, Heart Conduction System, Physiology (medical), Internal medicine, Animal model of cardiovascular disease, Cardiac conduction, medicine, Repolarization, Animals, Genetic Predisposition to Disease, Lamin A/C, Hutchinson–Gilford progeria syndrome, business.industry, Arrhythmias, Cardiac, Original Articles, medicine.disease, Mice, Mutant Strains, Disease Models, Animal, Mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f24170b70fb89a7a0130672f81004c0Test
https://pubmed.ncbi.nlm.nih.gov/33624748Test

المؤلفون: Fan Yang, Minjuan Zheng, Hong-Ping Song, Dang-Jie Wu, Wen-Qing Gong, Ying Zhang, Xin Sun, Xiaoni Zhao

المصدر: BioMed Research International, Vol 2020 (2020)
BioMed Research International

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Aging, congenital, hereditary, and neonatal diseases and abnormalities, Longitudinal strain, Article Subject, Heart Ventricles, 030204 cardiovascular system & hematology, Pulse Wave Analysis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Progeria, Internal medicine, medicine, Humans, Child, Aged, Ejection fraction, General Immunology and Microbiology, integumentary system, business.industry, Ultrasound, Infant, nutritional and metabolic diseases, Stroke Volume, General Medicine, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Carotid Arteries, Ventricle, Child, Preschool, Normal children, Cardiology, Elasticity Imaging Techniques, Medicine, Female, Abnormality, business, Hutchinson Gilford Progeria Syndrome, Research Article

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c592e62df5f2c4176dc4384c32fd98Test
https://doaj.org/article/f1056ec66909400f964656e70b2c9190Test

المؤلفون: Jieun Kim, Soo Yong Lee, So-mi Kang, Jeong Su Kim, Bum-Joon Park, Tae Sung Hwang, Nam-Chul Ha, Soyoung Park, Min-Ho Yoon, Seock Yong Kang, Jinsook Ahn, Tae-Gyun Woo, Jeongmin Joo, So-Young Kim, Kyu Jin Chung, Gyu-Yong Song, Jung-Hyun Cho, So Yon An, Ah-Young Oh

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Communications Biology

مصطلحات موضوعية: Senescence, Male, Adolescent, QH301-705.5, Primary Cell Culture, Drug Evaluation, Preclinical, Medicine (miscellaneous), General Biochemistry, Genetics and Molecular Biology, Mice, Progeria, Medicine, Animals, Humans, Biology (General), Author Correction, Child, business.industry, Drug discovery, Premature senescence, Progerin, Lamin Type A, Phenotype, Disease Models, Animal, HEK293 Cells, Cancer research, Female, General Agricultural and Biological Sciences, business, Hutchinson Gilford Progeria Syndrome, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67dd7878c23d025b86efe71ac12d92cTest
https://doaj.org/article/6f0c7f74aeec45738af0d9e5e5954b00Test

المؤلفون: Elba Expósito, Jesús Ruiz-Cabello, Amanda Sánchez-López, Manuel Desco, Gabriela Guzmán-Martínez, Richard K. Assoian, Lorena Cussó, Mercedes Salaices, Ana M. Briones, Lara del Campo, Ryan A. von Kleeck, Vicente Andrés, Cristina González-Gómez

المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), National Institutes of Health (Estados Unidos), Centro de Investigación Biomédica en Red - CIBERCV (Enfermedades Cardiovasculares), Instituto de Salud Carlos III, Fundación ProCNIC, UAM. Departamento de Farmacología

المصدر: Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Aging Cell

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Aging, Vascular smooth muscle, Medicina, Mice, Transgenic, Biology, Vascular stiffness, Muscle, Smooth, Vascular, Mice, 03 medical and health sciences, 0302 clinical medicine, Progeria, Internal medicine, medicine, Animals, Cell specific, Dietary nitrite, Sodium Nitrite, integumentary system, aging, progeria, vascular stiffness, Original Articles, Cell Biology, medicine.disease, Progerin, Magnetic Resonance Imaging, Dietary Nitrite, 3. Good health, smooth muscle cells, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, Smooth muscle cells, dietary nitrite, Arterial stiffness, Original Article, Hutchinson Gilford Progeria Syndrome, 030217 neurology & neurosurgery

وصف الملف: application/pdf; 15 págs.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67079faaebdce6e3b56c46cd7f9a823bTest
http://hdl.handle.net/20.500.12105/7720Test

المؤلفون: Gang Zhou, Ning Zhang, Jerry W. Shay, Sei Sho, Enzo Tedone, Tsung Po Lai, John P. Cooke, Ivone G. Bruno, Yanhui Li

المصدر: Aging Cell

مصطلحات موضوعية: 0301 basic medicine, Male, Telomerase, Pyridines, LMNA, 0302 clinical medicine, Progeria, Piperidines, Enzyme Inhibitors, Child, Cellular Senescence, integumentary system, Telomere, Progerin, Lamin Type A, Cell biology, Child, Preschool, Female, Original Article, Senescence, Adult, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, RNA therapy, Biology, Transfection, telomerase, Cell Line, 03 medical and health sciences, Hutchinson‐Gilford progeria syndrome, medicine, Farnesyltranstransferase, Humans, Telomerase reverse transcriptase, RNA, Messenger, Aged, aging, Infant, Newborn, nutritional and metabolic diseases, Infant, Telomere Homeostasis, Cell Biology, Original Articles, Fibroblasts, medicine.disease, telomeres, 030104 developmental biology, 030217 neurology & neurosurgery, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2a7073b3befb91dac3586d4981fd7aTest
https://pubmed.ncbi.nlm.nih.gov/31152494Test

المؤلفون: Leigh Atchison, Thomas J. Ribar, Nadia O. Abutaleb, George A. Truskey, Yantenew G. Gete, Kan Cao, Alim Ladha, Elizabeth Snyder-Mounts

المصدر: Stem Cell Reports
Stem Cell Reports, Vol 14, Iss 2, Pp 325-337 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Vasodilation, Biochemistry, tissue-engineered blood vessel, 0302 clinical medicine, Progeria, microphysiological system, Induced pluripotent stem cell, lcsh:QH301-705.5, lcsh:R5-920, integumentary system, Progerin, Tissue Donors, 3. Good health, Hutchinson-Gilford progeria syndrome, smooth muscle cells, medicine.anatomical_structure, Phenotype, medicine.symptom, lcsh:Medicine (General), vascular endothelium, Blood vessel, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Endothelium, induced pluripotent stem cells, Biology, Models, Biological, Article, shear stress, 03 medical and health sciences, Internal medicine, Genetics, medicine, Humans, Tissue Engineering, nutritional and metabolic diseases, Cell Biology, medicine.disease, Blood Vessel Prosthesis, Clone Cells, 030104 developmental biology, Endocrinology, lcsh:Biology (General), Gene Expression Regulation, Blood Vessels, 030217 neurology & neurosurgery, Vasoconstriction, Lamin, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bf348d3a2095ab6a1483794dde017eTest
https://pubmed.ncbi.nlm.nih.gov/32032552Test

المؤلفون: Balmus, Gabriel, Larrieu, Delphine, Barros, Ana C, Collins, Casey, Abrudan, Monica, Demir, Mukerrem, Geisler, Nicola J, Lelliott, Christopher J, White, Jacqueline K, Karp, Natasha A, Atkinson, James, Kirton, Andrea, Jacobsen, Matt, Clift, Dean, Rodriguez, Raphael, Sanger Mouse Genetics Project, Adams, David J, Jackson, Stephen P

المساهمون: Balmus, Gabriel [0000-0003-2872-4468], Larrieu, Delphine [0000-0002-2335-9361], Collins, Casey [0000-0002-5333-1116], Abrudan, Monica [0000-0003-0228-4353], Lelliott, Christopher J [0000-0001-8087-4530], Atkinson, James [0000-0002-7979-4960], Jacobsen, Matt [0000-0002-2713-1188], Rodriguez, Raphael [0000-0001-7668-446X], Apollo - University of Cambridge Repository

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, premature ageing, Science, LMNA, Kaplan-Meier Estimate, Hutchinson-Gilford Progeria Syndrome, Genomic Instability, N-Terminal Acetyltransferases, Mice, Progeria, Animals, Humans, lcsh:Science, N-Terminal Acetyltransferase A, Mice, Knockout, integumentary system, Hydrazones, nutritional and metabolic diseases, Aging, Premature, Lamin Type A, NAT10, Mice, Inbred C57BL, Disease Models, Animal, Thiazoles, Female, lcsh:Q, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed8f8bd77bbb0f7c0537defaa23ce66Test