المؤلفون: A C Sousa, Nerea Vazquez, Garikoitz Azkona, Blas Morales, Daniel Jimenez-Blasco, Patricia del Rio, Georg Auburger, Juan P. Bolaños, José Matías Arbelo, Amaia Zubiarrain, Rosario Sanchez-Pernaute, Rakel López de Maturana

المساهمون: European Commission, Ministerio de Economía y Competitividad (España), National Institutes of Health (US), German Research Foundation

المصدر: Molecular Neurobiology
Digital.CSIC. Repositorio Institucional del CSIC
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مصطلحات موضوعية: 0301 basic medicine, Male, Mutant, Cell, Induced Pluripotent Stem Cells, Neuroscience (miscellaneous), Down-Regulation, PINK1, Biology, medicine.disease_cause, Compound heterozygosity, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Article, 03 medical and health sciences, Exon, Cellular and Molecular Neuroscience, 0302 clinical medicine, Downregulation and upregulation, medicine, Humans, Neurons, Mutation, iPSC, Parkinson Disease, LRRK2, Fibroblasts, Middle Aged, Molecular biology, 3. Good health, nervous system diseases, Parkinson disease, 030104 developmental biology, medicine.anatomical_structure, Neurology, Female, Protein Kinases, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20291067c58dfaea45cf88d376c4e8dfTest
http://hdl.handle.net/10261/183206Test

المؤلفون: N. Hamscho, Francisco J. Barrero, Suzana Gispert, K. R. Kessler, Francisco Vives, Georg Auburger, C. Menzel, Blas Morales

المصدر: Journal of Neural Transmission. 112:1345-1353

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Pyrrolidines, Neurology, Dopamine, Genes, Recessive, Biology, medicine.disease_cause, Iodine Radioisotopes, Postsynaptic potential, Dopamine receptor D2, Internal medicine, medicine, Humans, Carbon Radioisotopes, PARKINSON'S SYNDROME, Biological Psychiatry, Dopamine transporter, Family Health, Tomography, Emission-Computed, Single-Photon, Genetics, Dopamine Plasma Membrane Transport Proteins, Mutation, Siblings, Dopaminergic, Parkinson Disease, Middle Aged, Corpus Striatum, Substantia Nigra, Psychiatry and Mental health, Endocrinology, Benzamides, biology.protein, Dopamine Antagonists, Female, Neurology (clinical), Protein Kinases, Function (biology), Tropanes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7027280171dd6a8805ebb0dca028732Test
https://doi.org/10.1007/s00702-005-0281-9Test

المؤلفون: Helmuth Steinmetz, Donat Kögel, Georg Auburger, Filomena Ricciardi, Michael Bonin, Olaf Riess, Alexander Kurz, Hans-Hermann Hoepken, Suzana Gispert, Michael Klinkenberg, Thomas Gasser, Mekhman Azizov, Blas Morales-Gordo

المصدر: Experimental neurology. 212(2)

مصطلحات موضوعية: Male, Programmed cell death, Time Factors, Glycine, PINK1, Biology, medicine.disease_cause, chemistry.chemical_compound, Developmental Neuroscience, Downregulation and upregulation, Gene expression, medicine, Humans, Fibroblast, Cells, Cultured, Aged, Alpha-synuclein, Family Health, Aspartic Acid, Neurodegeneration, Parkinson Disease, Fibroblasts, Middle Aged, medicine.disease, Mitochondria, medicine.anatomical_structure, Neurology, chemistry, Gene Expression Regulation, Immunology, Mutation, Cancer research, alpha-Synuclein, Female, Protein Kinases, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985246b805ac8b7c26f897428c076272Test
https://pubmed.ncbi.nlm.nih.gov/19166835Test

المؤلفون: Suzana Gispert, Blas Morales, Alexei P. Kudin, Ulrich Brandt, Oliver Wingerter, Hans-Hermann Hoepken, Alexander Mülsch, Stefan Dröse, Klaus Müller, Robert L. Nussbaum, Wolfram S. Kunz, Georg Auburger, Domenico Del Turco, Thomas Deller, Brunhilde Wirth

المصدر: Neurobiology of Disease, Vol 25, Iss 2, Pp 401-411 (2007)

مصطلحات موضوعية: MnSOD, Adult, Male, medicine.medical_specialty, Antioxidant, medicine.medical_treatment, Glutathione reductase, Substantia nigra, PINK1, Mitochondrion, Biology, medicine.disease_cause, lcsh:RC321-571, Lipid peroxidation, chemistry.chemical_compound, Superoxides, Malondialdehyde, Internal medicine, medicine, Humans, Lymphocytes, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Cell Line, Transformed, Electron Transport Complex I, Superoxide Dismutase, Parkinson Disease, Glutathione, Fibroblasts, Middle Aged, Mitochondria, Oxidative Stress, Endocrinology, Neurology, chemistry, Biochemistry, Female, Lipid Peroxidation, Protein Kinases, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30655712f53a28d63cc5520ea8afb8c2Test
https://pubmed.ncbi.nlm.nih.gov/17141510Test

المؤلفون: Louis J. Ptáček, Ling Tang, Yong Huang, Beatrice F. Sorensen, Marc Abramowicz, Andrew H. Ahn, Patrick Van Bogaert, Hsien-Yang Lee, Ying Xu, Anthony E. Lang, Massimo Pandolfo, Yuri Averyanov, Hubert Kwieciński, Serenella Servidei, Andrzej Friedman, Georg Auburger, Michiko K. Bruno, Jørgen E. Nielsen, Ying-Hui Fu, David Grimes

مصطلحات موضوعية: Gene isoform, Central Nervous System, Male, medicine.medical_specialty, Paroxysmal nonkinesigenic dyskinesia, Physiological, Muscle Proteins, Biology, medicine.disease_cause, Stress, Hydroxyacylglutathione hydrolase, Mice, Stress, Physiological, Chorea, Internal medicine, medicine, Genetics, Animals, Humans, Protein Isoforms, Gene, Molecular Biology, In Situ Hybridization, Genetics (clinical), Mutation, Chromosome Mapping, Female, Pedigree, Sequence Analysis, DNA, General Medicine, DNA, medicine.disease, Settore MED/26 - NEUROLOGIA, Endocrinology, PNKD, Dyskinesia, medicine.symptom, Sequence Analysis, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c2e023ad8088dbe2c45611bf5fc0d7Test
http://hdl.handle.net/10807/115368Test

المؤلفون: Anindya Dehejia, Gudrun Ulm, Elisabeth Leroy, Christian Lavedan, Keith D. Wilkinson, Tanya Chernova, Sobhanadditya Jonnalagada, Thomas Gasser, Peter J. Steinbach, Eva Mezey, Michael J. Brownstein, Rebecca Boyer, G Harta, Georg Auburger, Mihael H. Polymeropoulos, Barbara Leube

المصدر: Nature. 395:451-452

مصطلحات موضوعية: Male, Parkinson's disease, Molecular Sequence Data, Ubiquitin C-Terminal Hydrolase, medicine.disease_cause, Catalysis, Mice, Ubiquitin, Escherichia coli, medicine, Animals, Humans, Point Mutation, Missense mutation, Amino Acid Sequence, Ubiquitins, Gene, Genetics, Mutation, Multidisciplinary, Base Sequence, biology, Point mutation, Brain, Parkinson Disease, DNA, Middle Aged, medicine.disease, Ubiquitin carboxy-terminal hydrolase L1, Recombinant Proteins, Rats, nervous system diseases, biology.protein, Cancer research, Female, Thiolester Hydrolases, Ubiquitin Thiolesterase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2ffcf5a0cee8889ee8c1459d9420f3Test
https://doi.org/10.1038/26652Test