المؤلفون: Dereck W. Paul, Jonathan Stevens, Jerome Ritz, Indira Guleria, Qiang Ke, Kai W. Wucherpfennig, Harvey Cantor, Il-Kyu Choi, Hye-Jung Kim, Zhuting Hu, Zhe Wang, Stacey M. Fernandes, Baochun Zhang, Min Hong, Jennifer R. Brown

المصدر: Nature

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Herpesvirus 4, Human, medicine.medical_treatment, T cell, OX40 Ligand, Biology, Major histocompatibility complex, Article, Viral Matrix Proteins, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, Antigens, Neoplasm, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Cytotoxic T cell, Cells, Cultured, B cell, B-Lymphocytes, Multidisciplinary, Immunotherapy, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, CD8, CD27 Ligand, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b0d97689ec6ba81f1875bd51d85596Test
https://doi.org/10.1038/s41586-020-03075Test-w

المؤلفون: Maxim N. Artyomov, Daniele Runci, Ilya Kizhvatov, Ruan F.V. Medrano, Kai W. Wucherpfennig, Danielle M. Lussier, Wei Meng, Cheryl F. Lichti, Kathleen C. F. Sheehan, Jeffrey P. Ward, Tyler Jacks, Alexander Chen, Adrienne M. Luoma, J. Michael White, Elise Alspach, Alexander P. Miceli, Matthew M. Gubin, Emil R. Unanue, Robert D. Schreiber, Michel DuPage, Ekaterina Esaulova, Anthony N. Vomund, Cora D. Arthur

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT

المصدر: PMC
Nature

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, CD8-Positive T-Lymphocytes, Major histocompatibility complex, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, Antigens, Neoplasm, Neoplasms, MHC class I, medicine, Animals, Humans, Muscle, Skeletal, Multidisciplinary, biology, business.industry, Immunogenicity, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Cancer, Neoplasms, Experimental, Immunotherapy, medicine.disease, 030104 developmental biology, biology.protein, Cancer research, business, CD8, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98cb1bdaed9042b4a16e69dd9e0c149Test
https://doi.org/10.1038/s41586-019-1671-8Test

المؤلفون: Max Heckler, Courtney T. Stump, Katherine S. Ventre, Li Qiang, Katelyn T. Byrne, Stephanie K. Dougan, Joseph D. Mancias, Daniel Heid, Lestat R. Ali, Aladdin M. Bhuiyan, Tamara Biary, Annan Yang, Patrick T. Bruck, Svenja L. Nopper, Jana F. Tegethoff, Jinyang Li, Marc Pelletier, Ben Z. Stanger, Kevin Roehle, Anže Godicelj, James J. Akin, Patrick J Lenehan, Michael Dougan, Judith Agudo, Kai W. Wucherpfennig, Maria Quiles Del Rey, Adrienne M. Luoma, Stephanie J. Crowley, Gabrielle Ro

المصدر: Sci Transl Med

مصطلحات موضوعية: T cell, T-Lymphocytes, Major histocompatibility complex, Inhibitor of apoptosis, Article, Inhibitor of Apoptosis Proteins, Interferon-gamma, Mice, Immune system, Neoplasms, MHC class I, medicine, Cytotoxic T cell, Animals, Humans, Phagocytes, biology, Chemistry, Macrophages, Histocompatibility Antigens Class I, NF-kappa B, General Medicine, Cellular Reprogramming, Blockade, medicine.anatomical_structure, Cancer research, biology.protein, Immunotherapy, Checkpoint Blockade Immunotherapy, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53d8b17fad8bce1af5dcb723ab06941Test
https://europepmc.org/articles/PMC8406785Test/

المؤلفون: Zeina El Habre, Vladimir Vrbanac, Eric Spierings, Loes Plaisier, Juanjo Cragnolini, Catharina H. M. J. Van Elssen, Hidde L. Ploegh, Kai W. Wucherpfennig, Andrew M. Tager, Mohammad Rashidian, Jana Sticht, Johanne T. Jacobsen, Christian Freund, Jessica R. Ingram

المساهمون: MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), RS: FHML non-thematic output

المصدر: Journal of Nuclear Medicine, 58(6), 1003-1008. Society of Nuclear Medicine and Molecular Imaging

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, POSITRON EMISSION TOMOGRAPHY, Immunology, Graft vs Host Disease, medicine.disease_cause, Major histocompatibility complex, ImmunoPET, Autoimmunity, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, single domain antibodies, Immunity, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, PEPTIDE, IN-VIVO, Mice, Knockout, GvHD, MAGIC BULLET, biology, business.industry, Histocompatibility Antigens Class II, CLASS-II EXPRESSION, Single-Domain Antibodies, medicine.disease, CANCER, Immunity, Innate, MICE, 030104 developmental biology, Graft-versus-host disease, humanized mice, PET, ANTIBODY FRAGMENTS, 030220 oncology & carcinogenesis, Positron-Emission Tomography, Humanized mouse, biology.protein, Antibody, Radiopharmaceuticals, business, GENERATION

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88665969fe3297a0c858e10c4ea1560Test
https://cris.maastrichtuniversity.nl/en/publications/44b1f254-c6dd-46e9-bb5b-d8ce0551051bTest

المؤلفون: Kai W. Wucherpfennig, Nouran S. Abdelfattah, Charlotte I. Wang, Herbert Kim Lyerly, Zachary C. Hartman, Stephen J. Elledge, Tomasz Kula, Mohammad Haj Dezfulian

المصدر: Cell. 178(4)

مصطلحات موضوعية: T cell, Receptors, Antigen, T-Cell, Epitopes, T-Lymphocyte, Genes, MHC Class I, Endogeny, Blood Donors, Computational biology, Biology, CD8-Positive T-Lymphocytes, medicine.disease_cause, Major histocompatibility complex, Transfection, Genome, General Biochemistry, Genetics and Molecular Biology, Granzymes, Autoimmunity, 03 medical and health sciences, T-Cell Epitopes, Gene Knockout Techniques, 0302 clinical medicine, Antigen, Antigens, Neoplasm, HLA Antigens, Transduction, Genetic, medicine, Humans, 030304 developmental biology, 0303 health sciences, Antigen Presentation, T-cell receptor, Neoplasm Proteins, medicine.anatomical_structure, HEK293 Cells, biology.protein, Female, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ecb12cd3725e653d79fa8772066706Test
https://pubmed.ncbi.nlm.nih.gov/31699586Test

المؤلفون: Ludvig M. Sollid, Wouter Pos, Kai W. Wucherpfennig

المصدر: Current Opinion in Immunology. 31:24-30

مصطلحات موضوعية: Autoimmune disease, Genetics, Extramural, Immunology, chemical and pharmacologic phenomena, Biology, medicine.disease, Major histocompatibility complex, Article, Autoimmune Diseases, Histocompatibility, Major Histocompatibility Complex, Pathogenesis, Human disease, Histocompatibility Antigens, medicine, biology.protein, Animals, Humans, Immunology and Allergy, Allele, Genetic association

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5fed989791dbf3d9ccfb812eaabaf5Test
https://doi.org/10.1016/j.coi.2014.08.005Test

المؤلفون: Jessica Dobbins, Juan L. Mendoza, Sethi Dhruv Kam, Engin Özkan, Jacob Glanville, K. Christopher Garcia, Shen Dong, Kai W. Wucherpfennig, Mark M. Davis, Michael E. Birnbaum

المصدر: Cell. 157:1073-1087

مصطلحات موضوعية: Models, Molecular, T-Lymphocytes, T cell, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Human leukocyte antigen, Cross Reactions, Biology, Ligands, Major histocompatibility complex, Article, General Biochemistry, Genetics and Molecular Biology, Mice, Immune system, Antigen, HLA Antigens, Peptide Library, medicine, Animals, Humans, Amino Acid Sequence, Peptide library, Peptide sequence, Genetics, Biochemistry, Genetics and Molecular Biology(all), T-cell receptor, High-Throughput Nucleotide Sequencing, hemic and immune systems, medicine.anatomical_structure, biology.protein, Peptides, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2925c5643f2f854949c4d51a58ec9466Test
https://doi.org/10.1016/j.cell.2014.03.047Test

المؤلفون: David L. Stokes, Jones Tsai, Eric W. Roth, Michael L. Dustin, Kai W. Wucherpfennig, Jaime Llodra, Susana Gordo, Lance C. Kam, Kaushik Choudhuri

المصدر: Nature

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, Cellular immunity, Immunological Synapses, Receptors, Antigen, T-Cell, Vesicular Transport Proteins, Antigen-Presenting Cells, chemical and pharmacologic phenomena, Biology, Lymphocyte Activation, Major histocompatibility complex, gag Gene Products, Human Immunodeficiency Virus, Article, Immunological synapse, Mice, Immune system, Animals, Humans, TSG101, Virus Release, B-Lymphocytes, Multidisciplinary, Endosomal Sorting Complexes Required for Transport, Secretory Vesicles, Histocompatibility Antigens Class I, T-cell receptor, Cell Polarity, HIV, Intercellular Adhesion Molecule-1, Microvesicles, 3. Good health, Cell biology, DNA-Binding Proteins, Protein Transport, biology.protein, Female, Protein Binding, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8218dcbf5e1709002eb637d88c21617Test
https://doi.org/10.1038/nature12951Test

المؤلفون: Lars Fugger, Kai W. Wucherpfennig, Lars S. Madsen, Arne Svejgaard, Christina Andersson, E. Yvonne Jones, Karl Harlos, John I. Bell, Heather L.E. Lang, David I. Stuart, Helle Jacobsen, Shinji Ikemizu, Peter Hjorth, Leif Søndergaard

المصدر: Lang, H L E, Jacobsen, H, Ikemizy, S, Anderson, C, Harlos, K, Madsen, L, Hjorth, J P, Søndergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D I, Bell, J I, Jones, E Y & Fugger, L H 2002, ' A functional and structural basis for TCR cross-reactivity in multiple sclerosis ', Nature Immunology, vol. 3, pp. 940-943 .

مصطلحات موضوعية: Models, Molecular, Herpesvirus 4, Human, Linkage disequilibrium, Multiple Sclerosis, Receptors, Antigen, T-Cell, alpha-beta, T cell, Immunology, Mice, Transgenic, Human leukocyte antigen, Cross Reactions, Crystallography, X-Ray, medicine.disease_cause, Major histocompatibility complex, Cell Line, Mice, medicine, Animals, Humans, Immunology and Allergy, Genetics, B-Lymphocytes, MHC class II, biology, T-cell receptor, Myelin Basic Protein, HLA-DR Antigens, Protein Structure, Tertiary, Myelin basic protein, HLA-DRB5 Chains, Molecular mimicry, medicine.anatomical_structure, biology.protein, HLA-DRB1 Chains

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09cc4fdc01c312d86a4f6759d0a2f80Test
https://doi.org/10.1038/ni835Test

المؤلفون: Kai W. Wucherpfennig, Sethi Dhruv Kam

مصطلحات موضوعية: T cell, CD3, T-cell receptor, hemic and immune systems, chemical and pharmacologic phenomena, Biology, Ligand (biochemistry), Major histocompatibility complex, Immunological synapse, Cell biology, medicine.anatomical_structure, Immunoreceptor tyrosine-based activation motif, medicine, biology.protein, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8a44dcd6447396de7c28259e213cf2bfTest
https://doi.org/10.1016/b978-0-12-374279-7.05008-6Test