نتائج البحث - "Genetics, Genomics, and Proteomics"

1

Predictive value of EGFR mutation in non–small‐cell lung cancer patients treated with platinum doublet postoperative chemotherapy

المصدر: Cancer Science

مصطلحات موضوعية: Genetics, Genomics and Proteomics, Male, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.drug_class, medicine.medical_treatment, next‐generation sequencing, non‐squamous non–small‐cell lung cancer, Pemetrexed, Vinorelbine, medicine.disease_cause, postoperative chemotherapy, Tyrosine-kinase inhibitor, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Precision Medicine, Lung cancer, Cisplatin, Chemotherapy, business.industry, High-Throughput Nucleotide Sequencing, Original Articles, Sequence Analysis, DNA, General Medicine, Prognosis, medicine.disease, Survival Analysis, ErbB Receptors, Treatment Outcome, Chemotherapy, Adjuvant, Mutation, Biomarker (medicine), Original Article, Female, KRAS, EGFR mutation, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ca09f58c4088f4c7865801d9b76203Test
https://doi.org/10.1111/cas.15171Test

2

Highly sensitive fusion detection using plasma cell‐free RNA in non‐small‐cell lung cancers

المؤلفون: Yuki Shinno, Yuki Kojima, Kana Kurokawa, Shinji Kohsaka, Kan Yonemori, Fumiyuki Takahashi, Kazuhisa Takahashi, Tsuyoshi Saito, Nobuhiko Hasegawa, Takehito Shukuya, Takuo Hayashi, Yasushi Goto, Muneaki Ishijima, Hiroyuki Mano, Masahito Kawazu, Yoshiyuki Suehara, Shinya Kojima, Toshihide Ueno, Ikuko Takeda Nakamura

المصدر: Cancer Science

مصطلحات موضوعية: Genetics, Genomics and Proteomics, Male, Cancer Research, Lung Neoplasms, cell‐free RNA, Oncogene Proteins, Fusion, Biopsy, Plasma cell, Fusion gene, Piperidines, Carcinoma, Non-Small-Cell Lung, Anaplastic Lymphoma Kinase, cell‐free DNA, non‐small‐cell lung cancer, Lung, Aged, 80 and over, High-Throughput Nucleotide Sequencing, General Medicine, Middle Aged, Protein-Tyrosine Kinases, medicine.anatomical_structure, fusion gene, Oncology, Cell-free fetal DNA, Disease Progression, Original Article, Female, Gene Fusion, Cell-Free Nucleic Acids, Tyrosine kinase, Adult, Carbazoles, Sensitivity and Specificity, Crizotinib, Proto-Oncogene Proteins, Biomarkers, Tumor, ROS1, medicine, Humans, RNA, Messenger, Liquid biopsy, Lung cancer, Protein Kinase Inhibitors, Aged, liquid biopsy, business.industry, Proto-Oncogene Proteins c-ret, Original Articles, medicine.disease, Cytoskeletal Proteins, Drug Resistance, Neoplasm, Cancer research, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), business, Progressive disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fffd50c2a584473e681144a0e11852Test
https://doi.org/10.1111/cas.15084Test

3

Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single‐cell level

المؤلفون: Yuki Shinno, Hiroyuki Mano, Fumiyuki Takahashi, Takuo Hayashi, Yuki Kojima, Kazuya Takamochi, Ikuko Takeda Nakamura, Shinji Kohsaka, Masahito Kawazu, Yasushi Goto, Nobuhiko Hasegawa, Toshihide Ueno, Shigehiro Yagishita, Masachika Ikegami, Kazuhisa Takahashi

المصدر: Cancer Science

مصطلحات موضوعية: Genetics, Genomics and Proteomics, Male, 0301 basic medicine, Cancer Research, Lung Neoplasms, Oncogene Proteins, Fusion, Pleural effusion, Somatic cell, Cell Separation, medicine.disease_cause, Negative selection, Exon, 0302 clinical medicine, Circulating tumor cell, Piperidines, Anaplastic Lymphoma Kinase, Aged, 80 and over, Mutation, High-Throughput Nucleotide Sequencing, Exons, General Medicine, Middle Aged, Cell sorting, Neoplastic Cells, Circulating, floating tumor cells, Oncology, 030220 oncology & carcinogenesis, Keratins, Original Article, Female, Adult, molecular profiling, Carbazoles, Antineoplastic Agents, circulating tumor cells, Adenocarcinoma, Biology, 03 medical and health sciences, Crizotinib, medicine, Humans, Liquid biopsy, Protein Kinase Inhibitors, Aged, liquid biopsy, Immunomagnetic Separation, Gene Expression Profiling, Gene Amplification, Original Articles, DNA, Genes, erbB-1, lung adenocarcinoma, medicine.disease, Pleural Effusion, Malignant, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, Leukocyte Common Antigens, Gene Deletion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad82b208121e330f61e9205fd1083bfTest
https://doi.org/10.1111/cas.14821Test

4

Elevated TRIM23 expression predicts cisplatin resistance in lung adenocarcinoma

المؤلفون: Youwei Zhang, Yang Li, Sanyuan Sun, He Du, Yuan Yuan, Bi Chen

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Lung Neoplasms, Cellular differentiation, Mice, 0302 clinical medicine, Genetics, Genomics, and Proteomics, Aged, 80 and over, Gene knockdown, biology, Chemistry, NF-kappa B, High-Throughput Nucleotide Sequencing, General Medicine, glycolysis, Middle Aged, Up-Regulation, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, Signal Transduction, medicine.drug, Adult, Adenocarcinoma, resistance, 03 medical and health sciences, GTP-Binding Proteins, Cell Line, Tumor, medicine, Animals, Humans, Aged, Cell Proliferation, A549 cell, Cisplatin, Oncogene, Cell growth, Gene Expression Profiling, NF‐κB, Original Articles, lung adenocarcinoma, Survival Analysis, Glucose, 030104 developmental biology, A549 Cells, Drug Resistance, Neoplasm, Cell culture, Cancer research, biology.protein, TRIM23, GLUT1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adb3ec1af5e69781842b1b5a0546ba5Test
https://doi.org/10.1111/cas.14226Test

5

Impacts of NRF2 activation in non–small‐cell lung cancer cell lines on extracellular metabolites

المؤلفون: Sakae Saito, Hirofumi Ishii, Ikuko N. Motoike, Mikiko Suzuki, Kengo Kinoshita, Fumiki Katsuoka, Daisuke Saigusa, Yuichi Aoki, Michael Zorzi, Hiroshi Kitamura, Masayuki Yamamoto, Hozumi Motohashi

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, NF-E2-Related Factor 2, non–small‐cell lung cancer, culture supernatant, Biology, digestive system, environment and public health, NRF2, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Exome Sequencing, Carcinoma, medicine, Humans, Metabolomics, Gene Regulatory Networks, Lung cancer, Genetics, Genomics, and Proteomics, Exome, metabolites, Kelch-Like ECH-Associated Protein 1, Gene Expression Profiling, Large cell, Original Articles, General Medicine, respiratory system, Cullin Proteins, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Mutation, Cancer cell, Cancer research, Adenocarcinoma, Original Article, metabolome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ed5789a9b4bb3f337b9dda8a6e4221Test
https://doi.org/10.1111/cas.14278Test

6

Potential mechanism of primary resistance to icotinib in patients with advanced non–small cell lung cancer harboring uncommon mutant epidermal growth factor receptor: A multi‐center study

المؤلفون: Yong Fang, Yinbin Zhang, Chunwei Xu, You-cai Zhu, Tangfeng Lv, Jinluan Li, Liping Wang, Lei Lei, Wu Zhuang, Xiao‐jia Wang, Mei‐yu Fang, Yong Song, Hong Wang, Wenxian Wang

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, next‐generation sequencing, Targeted therapy, Circulating Tumor DNA, 0302 clinical medicine, non–small cell lung cancer, Carcinoma, Non-Small-Cell Lung, Crown Ethers, Gene Regulatory Networks, Epidermal growth factor receptor, Genetics, Genomics, and Proteomics, education.field_of_study, biology, High-Throughput Nucleotide Sequencing, General Medicine, ErbB Receptors, Oncology, 030220 oncology & carcinogenesis, Disease Progression, Original Article, Female, Tyrosine kinase, China, Population, 03 medical and health sciences, icotinib, medicine, PTEN, Humans, education, Lung cancer, Retrospective Studies, Chemotherapy, business.industry, Original Articles, ctDNA, Sequence Analysis, DNA, medicine.disease, 030104 developmental biology, Drug Resistance, Neoplasm, Icotinib, Mutation, biology.protein, Cancer research, Quinazolines, business, epidermal growth factor receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd17a9c43ee1c4540943cf0750f683e5Test
http://europepmc.org/articles/PMC7004544Test

7

Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

المؤلفون: Michiru Nishita, Nawaphat Jangphattananont, Ryu Imamura, Junichi Takagi, Hiroki Sato, Yasuhiro Minami, Kunio Matsumoto, Wenyu Miao, Katsuya Sakai

المصدر: Cancer Science

مصطلحات موضوعية: Transcriptional Activation, 0301 basic medicine, Cancer Research, Cell signaling, Lung Neoplasms, Sema domain, Mutation, Missense, CHO Cells, medicine.disease_cause, Receptor tyrosine kinase, Gene Knockout Techniques, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Protein Domains, Loss of Function Mutation, Epidermal growth factor, Cell Line, Tumor, medicine, Extracellular, Animals, Humans, Protein Kinase Inhibitors, Genetics, Genomics, and Proteomics, Mutation, biology, Chemistry, missense mutation, Original Articles, General Medicine, Proto-Oncogene Proteins c-met, 030104 developmental biology, hepatocyte growth factor, MET receptor, Oncology, loss of function, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Cancer research, Original Article, Hepatocyte growth factor, affinity, Protein Multimerization, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a869166f812238144a77c2c157b3b09Test
http://www.lib.kobe-u.ac.jp/handle_kernel/90006394Test

8

Molecular and clinical analysis of Chinese patients with anaplastic lymphoma kinase (ALK)‐rearranged non‐small cell lung cancer

المؤلفون: Hong Pan, Jiawei Shou, Huanqing Cheng, Wenfeng Li, Chunwei Xu, Shanbo Cao, Xiuyu Cai, Qian Chu, Hongming Pan, Qinhong Zhen, Chuangzhou Rao, Xiaoyun Zhou, Hongsen Li, Jin Sheng, Shengxiang Ren, Yong Fang, Yue-Fen Zhou, Tao Sun, Huina Wang, Feng Lou, Wenxian Wang

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Lung Neoplasms, Oncogene Proteins, Fusion, next‐generation sequencing, Tp53 mutation, Translocation, Genetic, 0302 clinical medicine, Gene Frequency, Epidermal growth factor, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Prospective Studies, Genetics, Genomics, and Proteomics, Aged, 80 and over, Gene Rearrangement, circulating tumor DNA, education.field_of_study, Clinical pathology, High-Throughput Nucleotide Sequencing, General Medicine, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Female, Original Article, Non small cell, Adult, non‐small cell lung cancer, medicine.medical_specialty, Population, 03 medical and health sciences, Age Distribution, Asian People, medicine, Humans, Lung cancer, education, Aged, business.industry, Breakpoint, tissue, Sequence Analysis, DNA, Original Articles, medicine.disease, 030104 developmental biology, ALK, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c5e586832437ec9ff4350be6a18897Test
https://doi.org/10.1111/cas.14177Test

9

Circular RNA circCRIM1 inhibits invasion and metastasis in lung adenocarcinoma through the microRNA (miR)‐182/miR‐93‐leukemia inhibitory factor receptor pathway

المؤلفون: Yingkuan Liang, Hongyu Shen, Lin Xu, Lin Wang, Qixing Mao, Feng Jiang, Gaochao Dong, Bing Chen, Wenjie Xia

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, Leukemia Inhibitory Factor Receptor alpha Subunit, Leukemia inhibitory factor receptor, medicine.disease_cause, Corrections, Metastasis, 0302 clinical medicine, RNA, Small Interfering, Lung, Genetics, Genomics, and Proteomics, General Medicine, Middle Aged, Prognosis, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Adenocarcinoma, Female, Original Article, leukemia inhibitory factor receptor, Mice, Nude, Adenocarcinoma of Lung, Biology, circCRIM1, 03 medical and health sciences, Downregulation and upregulation, Circular RNA, Cell Line, Tumor, microRNA, medicine, Biomarkers, Tumor, Animals, Humans, Neoplasm Invasiveness, Cell Proliferation, has‐miR‐93 and has‐miR‐182, Membrane Proteins, Bone Morphogenetic Protein Receptors, RNA, Circular, Original Articles, medicine.disease, lung adenocarcinoma, Survival Analysis, Xenograft Model Antitumor Assays, invasion and metastasis, MicroRNAs, 030104 developmental biology, Tissue Array Analysis, Cancer cell, Cancer research, RNA, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fb840c5db09f2c8553e55333dfbac7Test
http://europepmc.org/articles/PMC6726696Test

10

Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing

المؤلفون: Hiroyuki Mano, Daiya Takai, Yoshihisa Hiraishi, Jiro Sato, Shinji Kohsaka, Hidenori Kage, Jun Nakajima, Tetsuo Ushiku, Kiyoshi Miyagawa, Takahide Nagase, Aya Shinozaki-Ushiku, Hiroyuki Aburatani, Kazuhiro Nagayama

المصدر: Cancer Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ce8dae4cd4246bde2d3c51b7ac49dbTest
http://europepmc.org/articles/PMC6676108Test

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