التفاصيل البيبلوغرافية
| العنوان: |
Wedge Resection versus Stereotactic Body Radiation Therapy for Non-Small Cell Lung Cancer Tumors ≤8 mm. |
| المؤلفون: |
Mansur, Arian, Saleem, Zain, Beqari, Jorind, Mathey-Andrews, Camille, Potter, Alexandra L., Cranor, James, Nees, Alexandra T., Srinivasan, Deepti, Yang, Margaret E., Yang, Chi-Fu Jeffrey, Auchincloss, Hugh G. |
| المصدر: |
Current Oncology; Mar2024, Vol. 31 Issue 3, p1529-1542, 14p |
| مصطلحات موضوعية: |
STEREOTACTIC radiotherapy, NON-small-cell lung carcinoma, LUNG tumors, RADIOTHERAPY, PROPORTIONAL hazards models, DISEASE risk factors |
| مستخلص: |
The objective of this study was to evaluate the overall survival of patients with ≤8 mm non-small cell lung cancer (NSCLC) who undergo wedge resection versus stereotactic body radiation therapy (SBRT). Kaplan–Meier analysis, multivariable Cox proportional hazards modeling, and propensity score-matched analysis were performed to evaluate the overall survival of patients with ≤8 mm NSCLC in the National Cancer Database (NCDB) from 2004 to 2017 who underwent wedge resection versus patients who underwent SBRT. The above-mentioned matched analyses were repeated for patients with no comorbidities. Patients who were coded in the NCDB as having undergone radiation because surgery was contraindicated due to patient risk factors (e.g., comorbid conditions, advance age, etc.) and those with a history of prior malignancy were excluded from analysis. Of the 1505 patients who had NSCLC ≤8 mm during the study period, 1339 (89%) patients underwent wedge resection, and 166 (11%) patients underwent SBRT. In the unadjusted analysis, multivariable Cox modeling and propensity score-matched analysis, wedge resection was associated with improved survival when compared to SBRT. These results were consistent in a sensitivity analysis limited to patients with no comorbidities. [ABSTRACT FROM AUTHOR] |
|
Copyright of Current Oncology is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder