دورية أكاديمية
Evaluation of extensively drug-resistant gram-negative bacteremia among solid-organ transplant recipients: a multicenter study
| العنوان: | Evaluation of extensively drug-resistant gram-negative bacteremia among solid-organ transplant recipients: a multicenter study |
|---|---|
| المؤلفون: | Yanik Yalcin, Tugba, Azap, Ozlem, Kose, Adem, Bayindir, Yasar, Saricaoglu, Elif Mukime, Cinar, Gule, Uygun Kizmaz, Yesim, KurSun, Ebru, Aliskan, Hikmet Eda, Tezer Tekce, Yasemin, Eren Kutsoylu, Oya Ozlem, EgelI, Tufan, Ari, Alpay, Albayrak, Yurdagul, Cabadak, Hatice, Demir Onder, Kubra, KizilateS, Filiz, Ozger, Selcuk, Guzel Tunccan, Ozlem, Haberal, Mehmet, Deniz, Secil |
| بيانات النشر: | Tubitak Scientific & Technical Research Council Turkey |
| سنة النشر: | 2021 |
| المجموعة: | Pamukkale University Repository / Pamukkale Üniversitesi Açık Erişim Arşivi |
| مصطلحات موضوعية: | Solid-organ transplant recipients, drug-resistant, bacteremia, Blood-Stream Infection, Outcomes, Liver |
| الوصف: | Background/aim: The aim of this study is to evaluate the distribution, sources, clinical features, and mortality rates of bacteremia due to evaluation of extensively drug-resistant (XDR) gram negative among solid-organ transplant (SOT) recipients. Materials and methods: A retrospective study of SOT recipients with bacteremia due to XDR gram-negative pathogens in 11 centers between 2016 and 2018 was conducted. Patients' records were evaluated. Results: Of 171 bacteremia that occurred in 164 SOT recipients, 93 (56.7%) were liver, 46 (28%) kidney, 14 (8.5%) heart, and 11 (6.7%) lung recipients. Bacteremia episodes were recorded in the first year in 63.7% of the patients (n = 109), early-onset bacteremia was recorded in 45% (n = 77) of the episodes. In multivariate analysis, catheter-associated bacteremia was an independent risk factor for 7-day mortality (p = 0.037), and early-onset bacteremia was found as an independent risk factor for 30-day mortality (p = 0.017). Conclusion: Difficult-to-treat infections due to XDR bacteria in SOT recipients shadow the success of transplantation. Central venous catheters seem to be the main risk factor. Judicious use of medical devices is of pivotal importance. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1300-0144 1303-6165 |
| العلاقة: | Turkish Journal Of Medical Sciences; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.3906/sag-2101-161Test; https://search.trdizin.gov.tr/yayin/detay/480657Test; https://hdl.handle.net/11499/46081Test; 51; 1960; 1968; 2-s2.0-85114851700; WOS:000691544700047 |
| DOI: | 10.3906/sag-2101-161 |
| الإتاحة: | https://doi.org/10.3906/sag-2101-161Test https://hdl.handle.net/11499/46081Test https://search.trdizin.gov.tr/yayin/detay/480657Test |
| حقوق: | open |
| رقم الانضمام: | edsbas.B93F03A2 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 13000144 13036165 |
|---|---|
| DOI: | 10.3906/sag-2101-161 |