نتائج البحث - "Lipoxygenase"

1

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase

المساهمون: Pein, Helmut, Ville, Alexia, Pace, Simona, Temml, Veronika, Garscha, Ulrike, Raasch, Martin, Alsabil, Khaled, Viault, Guillaume, Dinh, Chau-Phi, Guilet, David, Troisi, Fabiana, Neukirch, Konstantin, König, Stefanie, Bilancia, Rosella, Waltenberger, Birgit, Stuppner, Hermann, Wallert, Maria, Lorkowski, Stefan, Weinigel, Christina, Rummler, Silke, Birringer, Marc, Roviezzo, Fiorentina, Sautebin, Lidia, Helesbeux, Jean-Jacque, Séraphin, Deni, Mosig, Alexander S., Schuster, Daniela, Rossi, Antonietta, Richomme, Pascal, Werz, Oliver, Koeberle, Andreas, Substances d'Origine Naturelle et Analogues Structuraux (SONAS), Université d'Angers (UA)

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.3834. ⟨10.1038/s41467-018-06158-5⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Metabolite, medicine.medical_treatment, General Physics and Astronomy, Pharmacology, chemistry.chemical_compound, Mice, 0302 clinical medicine, Leukocytes, Vitamin E, Lipoxygenase Inhibitors, lcsh:Science, Multidisciplinary, biology, Chemistry (all), Middle Aged, Recombinant Proteins, 3. Good health, Liver, 030220 oncology & carcinogenesis, Arachidonate 5-lipoxygenase, Metabolome, medicine.symptom, Bronchial Hyperreactivity, Adult, Cell signaling, Adolescent, Cell Survival, Science, Inflammation, Peritonitis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Physics and Astronomy (all), Inhibitory Concentration 50, Young Adult, Immune system, medicine, Animals, Humans, Aged, Biochemistry, Genetics and Molecular Biology (all), Arachidonate 5-Lipoxygenase, Cell-Free System, General Chemistry, Lipid signaling, 030104 developmental biology, chemistry, biology.protein, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfee7afdff0d4990f14ad8886b080055Test
http://link.springer.com/article/10.1038/s41467-018-06158-5Test

2

Zafirlukast in combination with pseudohypericin attenuates spinal cord injury and motor function in experimental mice

المؤلفون: Jin Sun, Xiao-Gang Chen, Shou-Guo Wang, Fu Hua, Hai-Tao Yue, Yong-yi Xu

المصدر: Drug Design, Development and Therapy

مصطلحات موضوعية: Male, Indoles, mice, zafirlukast, Phenylcarbamates, Pharmaceutical Science, Apoptosis, Inflammation, 030204 cardiovascular system & hematology, Pharmacology, Cys-LT, Neuroprotection, Tosyl Compounds, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Animals, Medicine, Lipoxygenase Inhibitors, 030212 general & internal medicine, Zafirlukast, Perylene, Spinal cord injury, Spinal Cord Injuries, Original Research, Sulfonamides, Leukotriene, Drug Design, Development and Therapy, TUNEL assay, pseudohypericin, biology, Tumor Necrosis Factor-alpha, business.industry, medicine.disease, Neutrophil Infiltration, Proto-Oncogene Proteins c-bcl-2, Arachidonate 5-lipoxygenase, biology.protein, 5-lipoxygenase, Leukotriene Antagonists, Drug Therapy, Combination, Tumor necrosis factor alpha, medicine.symptom, Corrigendum, business, medicine.drug

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7038cdeee643ee378d0c4460ae0dfdTest
http://europepmc.org/articles/PMC6078184Test

3

Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators

المؤلفون: Paul M. Jordan, Oliver Werz, Christian Kretzer, Kehong Zhang, Friedemann Börner, Dagmar Fischer, Robert K. Hofstetter, Xinchun Chen, Marianna Potenza, Wenfei Wang, Simona Pace, Nathaniel C. Gilbert, Jana Gerstmeier, Antonietta Rossi, Rossella Bilancia, Marcia E. Newcomer, Stefan Lorkowski

المساهمون: Pace, S., Zhang, K., Jordan, P. M., Bilancia, R., Wang, W., Borner, F., Hofstetter, R. K., Potenza, M., Kretzer, C., Gerstmeier, J., Fischer, D., Lorkowski, S., Gilbert, N. C., Newcomer, M. E., Rossi, A., Chen, X., Werz, O.

مصطلحات موضوعية: Male, 0301 basic medicine, Anti-Inflammatory Agents, Mice, chemistry.chemical_compound, 0302 clinical medicine, celastrol (PubChem CID: 122724), Lipoxygenase Inhibitors, Cells, Cultured, Leukotriene, biology, indomethacin (PubChem CID: 3715), Celastrol, Cell biology, Molecular Docking Simulation, 030220 oncology & carcinogenesis, Arachidonate 5-lipoxygenase, 5-lipoxygenase, resolvin D5 (PubChem CID: 16061139), dimethyl sulfoxide (PubChem CID: 679), medicine.symptom, zileuton (PubChem CID: 60490), Pentacyclic Triterpenes, Resolvin, Leukotrienes, Tripterygium, medicine.drug_class, Inflammation, MK886 (PubChem CID: 3651377), Anti-inflammatory, 03 medical and health sciences, In vivo, zymosan (PubChem CID: 64689), medicine, Animals, Humans, arachidonic acid (PubChem CID: 444899), Pharmacology, Arachidonate 5-Lipoxygenase, Specialized pro-resolving mediator, Lipid signaling, Lipid Metabolism, Biosynthetic Pathways, 030104 developmental biology, chemistry, biology.protein, celecoxib (PubChem CID: 2662)