دورية أكاديمية
Knowledge of liver fibrosis stage among adults with NAFLD/NASH improves adherence to lifestyle changes
| العنوان: | Knowledge of liver fibrosis stage among adults with NAFLD/NASH improves adherence to lifestyle changes |
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| المؤلفون: | Carrieri, Patrizia, Mourad, Abbas, Marcellin, Fabienne, Trylesinski, Aldo, Calleja, José, Luis, Protopopescu, Camelia, Lazarus, Jeffrey, V |
| المساهمون: | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des sciences de la santé publique Marseille (ISSPAM), Intercept Pharmaceuticals London, UK (IP), Hospital Universitario Puerta de Hierro-Majadahonda Madrid, Spain, Instituto de Salud Global - Institute For Global Health Barcelona (ISGlobal), University of Barcelona |
| المصدر: | ISSN: 1478-3223. |
| بيانات النشر: | HAL CCSD Wiley-Blackwell |
| سنة النشر: | 2022 |
| المجموعة: | Aix-Marseille Université: HAL |
| مصطلحات موضوعية: | cross-sectional study, lifestyle interventions, liver disease, patient-provider relationship, MESH: Adult, MESH: Biopsy, MESH: Cross-Sectional Studies, MESH: Humans, MESH: Life Style, MESH: Liver, MESH: Liver Cirrhosis, MESH: Non-alcoholic Fatty Liver Disease, MESH: Obesity, [SDV]Life Sciences [q-bio] |
| الوصف: | Background & Aims: Though lifestyle interventions can reverse disease progression in people with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/ NASH), unawareness about disease severity might compromise behavioural changes. Data from this first international cross-sectional survey of individuals with NAFLD/ NASH were used to identify correlates of both unawareness about fibrosis stage and its association with adherence to lifestyle adjustments. Methods: Adults with NAFLD/NASH registered on the platform Carenity were invited to participate in an online 20-min, six-section survey in Canada, France, Germany, Italy, Spain and the United Kingdom to describe their experience with NAFLD/NASH and its care (N = 1411). Weighted binary and multinomial logistic regressions were performed to estimate the effect of explanatory variables on unawareness of fibrosis stage and poor adherence to lifestyle changes respectively. Results: In the study group, 15.5% had obesity and 59.2% did not know their fibrosis stage. After multiple adjustments, individuals with a body mass index (BMI) ≥35 were over twice as likely to not know their fibrosis stage. People with a BMI >30 had a threefold higher risk of having poor adherence to lifestyle changes. Unawareness about fibrosis stage was also significantly associated with poor adherence to lifestyle adjustments. Conclusions: As fibrosis stage is becoming the main predictor of NAFLD progression, improving patient-provider communication-especially for people with obesityabout liver fibrosis stage, its associated risks and how to mitigate them, is needed. Training for healthcare professionals and promoting patient educational programmes to support behaviour changes should also be included in the liver health agenda. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35220673; inserm-04048027; https://inserm.hal.science/inserm-04048027Test; https://inserm.hal.science/inserm-04048027/documentTest; https://inserm.hal.science/inserm-04048027/file/Liver%20International%20-%202022%20-%20Carrieri.pdfTest; PUBMED: 35220673; PUBMEDCENTRAL: PMC9310954 |
| DOI: | 10.1111/liv.15209 |
| الإتاحة: | https://doi.org/10.1111/liv.15209Test https://inserm.hal.science/inserm-04048027Test https://inserm.hal.science/inserm-04048027/documentTest https://inserm.hal.science/inserm-04048027/file/Liver%20International%20-%202022%20-%20Carrieri.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.8045114B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/liv.15209 |
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