المؤلفون: Kit-Kay Mak, Zhang Shiming, Jun Sheng Low, Madhu Katyayani Balijepalli, Raghavendra Sakirolla, Albena T. Dinkova-Kostova, Ola Epemolu, Zulkefeli Mohd, Mallikarjuna Rao Pichika

المصدر: Molecules; Volume 27; Issue 15; Pages: 4992

مصطلحات موضوعية: Flavonoids, Lipopolysaccharides, Glycogen Synthase Kinase 3 beta, Kelch-Like ECH-Associated Protein 1, NF-E2-Related Factor 2, Organic Chemistry, Anti-Inflammatory Agents, NF-kappa B, Pharmaceutical Science, Nitric Oxide, Amides, Rats, Analytical Chemistry, Molecular Docking Simulation, Mice, Chemistry (miscellaneous), Drug Discovery, Animals, Cytokines, Humans, Molecular Medicine, Physical and Theoretical Chemistry, Heme Oxygenase-1, auranamide, patriscabratine, Melastoma malabathricum, NRF2, KEAP1, anti-inflammatory

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8826c704a8ff88a56dc443453de3304cTest

المؤلفون: Laura Casares, Rita Moreno, Kevin X. Ali, Maureen Higgins, Sharadha Dayalan Naidu, Graham Neill, Lena Cassin, Anders E. Kiib, Esben B. Svenningsen, Alberto Minassi, Tadashi Honda, Thomas B. Poulsen, Clotilde Wiel, Volkan I. Sayin, Albena T. Dinkova-Kostova, David Olagnier, Laureano de la Vega

المصدر: Casares, L, Moreno, R, Ali, K X, Higgins, M, Dayalan Naidu, S, Neill, G, Cassin, L, Kiib, A E, Svenningsen, E B, Minassi, A, Honda, T, Poulsen, T B, Wiel, C, Sayin, V I, Dinkova-Kostova, A T, Olagnier, D & de la Vega, L 2022, ' The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity ', Redox Biology, vol. 51, 102291 . https://doi.org/10.1016/j.redox.2022.102291Test
Casares, L, Moreno, R, Ali, K X, Higgins, M, Dayalan Naidu, S, Neill, G, Cassin, L, Kiib, A E, Svenningsen, E B, Minassi, A, Honda, T, Poulsen, T B, Wiel, C, Sayin, V I, Dinkova-Kostova, A T, Olagnier, D & de la Vega, L 2022, ' The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity ', Redox Biology, vol. 51, pp. 102291 . https://doi.org/10.1016/j.redox.2022.102291Test

مصطلحات موضوعية: Oxidative Stress, Kelch-Like ECH-Associated Protein 1, HMOX1, NF-E2-Related Factor 2, CDDO, Organic Chemistry, Clinical Biochemistry, BACH1, Oleanolic Acid, Biochemistry, Triterpenes, NRF2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155dea4f5960ffcc085d9f8477eae799Test
https://pure.au.dk/portal/da/publications/the-synthetic-triterpenoids-cddotfea-and-cddome-but-not-cddo-promote-nuclear-exclusion-of-bach1-impairing-its-activityTest(66402709-7e58-4b88-af6c-815f1189769a).html

المؤلفون: Sharadha Dayalan Naidu, Albena T. Dinkova-Kostova

المصدر: Open Biology
Open Biology, Vol 10, Iss 6 (2020)

مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, antioxidant, NF-E2-Related Factor 2, Immunology, Inflammation, Review, Review Article, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, NRF2, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, medicine, Humans, Molecular Targeted Therapy, lcsh:QH301-705.5, cysteine, Transcription factor, anti-inflammatory, 030304 developmental biology, Clinical Trials as Topic, 0303 health sciences, Kelch-Like ECH-Associated Protein 1, biology, General Neuroscience, Ubiquitination, respiratory system, KEAP1, Cytoprotection, Cell biology, Ubiquitin ligase, lcsh:Biology (General), redox, 030220 oncology & carcinogenesis, Chronic Disease, biology.protein, medicine.symptom, Cullin, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7017809c3d739b04628aa127f1f19a38Test
https://doi.org/10.1098/rsob.200105Test

المؤلفون: Albena T. Dinkova-Kostova, Filip Cvetko, Hiran A. Prag, Michael P. Murphy, Stuart T. Caldwell, Maureen Higgins, Takafumi Suzuki, Richard C. Hartley, Masayuki Yamamoto

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, GCLC, glutamate–cysteine ligase catalytic subunit, thiol oxidation, Mitochondrion, Biochemistry, FB, fractionation buffer, NQO1, NAD(P)H:quinone oxidoreductase-1, Mice, chemistry.chemical_compound, DNM1L, Superoxides, energy metabolism, Homeostasis, Hydrogen peroxide, Cells, Cultured, HO-1, heme oxygenase-1, NAC, N-acetyl-L-cysteine, SFN, sulforaphane, chemistry.chemical_classification, Kelch-Like ECH-Associated Protein 1, Nrf2, nuclear factor erythroid 2–related factor 2, respiratory system, DRP1, dynamin-related protein 1, Glutathione, Mitochondria, Cell biology, CDNB, 1-chloro-2,4-dinitrobenzene, Keap1, Kelch-like ECH-associated protein 1, TRX, thioredoxin, Thioredoxin, Oxidation-Reduction, Research Article, Signal Transduction, NF-E2-Related Factor 2, reactive oxygen species (ROS), Nrf2, MitoPQ, MitoParaquat, 03 medical and health sciences, MitoCDNB, CD, concentration required to double, ROS, reactive oxygen species, PGAM5, phosphoglycerate mutase family member 5, Animals, TRXR2, TRX reductase 2, Cysteine, Sulfhydryl Compounds, redox signaling, Molecular Biology, Reactive oxygen species, 030102 biochemistry & molecular biology, Cell Biology, ACN, acetonitrile, MitoCDNB, MitoChlorodinitrobenzoic acid, GSS, GSH synthetase, MEF, mouse embryonic fibroblast, KEAP1, 030104 developmental biology, chemistry, BSA, bovine serum albumin, MitoPQ

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0523882756133409621203d90cd5225Test
https://doi.org/10.1074/jbc.ra120.016551Test

المؤلفون: Albena T, Dinkova-Kostova, Rumen V, Kostov, Peter, Canning

المصدر: Archives of Biochemistry and Biophysics

مصطلحات موضوعية: Cell Nucleus, Inflammation, Models, Molecular, Keap1, Kelch-Like ECH-Associated Protein 1, NF-E2-Related Factor 2, Ubiquitin-Protein Ligases, Electrophiles, Cullin Proteins, Oxidants, Article, Nrf2, Oxygen, HEK293 Cells, Protein Domains, Cysteine sensor, Homeostasis, Humans, Cysteine, Protein Multimerization, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::ff34765924801611fb940903be9a2e44Test
https://pubmed.ncbi.nlm.nih.gov/27497696Test

المؤلفون: Sam Swift, Albena T. Dinkova-Kostova, Liam Baird, David Llères

المساهمون: Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

المصدر: Biotechnology Advances
Biotechnology Advances, Elsevier, 2014, 32 (6), pp.1133-1144. ⟨10.1016/j.biotechadv.2014.03.004⟩

مصطلحات موضوعية: FLIM, Keap1, RBX1, [SDV]Life Sciences [q-bio], Bioengineering, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Applied Microbiology and Biotechnology, environment and public health, Nrf2, Cell Line, chemistry.chemical_compound, Mice, Fluorescence Resonance Energy Transfer, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Transcription factor, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Binding Sites, Kelch-Like ECH-Associated Protein 1, Intracellular Signaling Peptides and Proteins, Signal transducing adaptor protein, respiratory system, Cell biology, Ubiquitin ligase, Rats, Förster resonance energy transfer, chemistry, NF-E2 Transcription Factor, p45 Subunit, Isothiocyanate, Research Review Paper, biology.protein, FRET, Cytoprotective enzymes, Signal transduction, Single-Cell Analysis, Sulforaphane, Biotechnology, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31380384f18f256d2657d8ed42bafedTest
https://hal.archives-ouvertes.fr/hal-03027057Test

المؤلفون: Stjepana, Kovac, Plamena R, Angelova, Kira M, Holmström, Ying, Zhang, Albena T, Dinkova-Kostova, Andrey Y, Abramov

المصدر: Biochimica et Biophysica Acta

مصطلحات موضوعية: Mice, Hairless, Keap1, Kelch-Like ECH-Associated Protein 1, NADPH oxidase, NF-E2-Related Factor 2, Intracellular Signaling Peptides and Proteins, NADPH Oxidases, ROS, NOX, respiratory system, digestive system, environment and public health, Article, Nrf2, Mitochondria, Mice, Cytosol, Animals, Reactive Oxygen Species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::df45a0e67812789299dbd6b553ef55cdTest
https://pubmed.ncbi.nlm.nih.gov/25484314Test