دورية أكاديمية

11C Click Chemistry Using [11C]Methyl Azide: Simplified, Versatile, and Practical Alternative Access to [11C]Nucleosides and [11C]Oligonucleotides for PET Imaging.

التفاصيل البيبلوغرافية
العنوان: 11C Click Chemistry Using [11C]Methyl Azide: Simplified, Versatile, and Practical Alternative Access to [11C]Nucleosides and [11C]Oligonucleotides for PET Imaging.
المؤلفون: Bordenave, Thomas1, Hazari, Puja Panwar2, James, Damien1, Mishra, Anil K.2, Szlosek‐Pinaud, Magali1 m.szlosek@ism.u‐bordeaux1.fr, Fouquet, Eric1 e.fouquet@ism.u‐bordeaux1.fr
المصدر: European Journal of Organic Chemistry. Mar2013, Vol. 2013 Issue 7, p1214-1217. 4p.
مستخلص: This communication reports the simplified formation of methyl azide and its use in the Huisgen cycloaddition for the rapid, efficient, and selective labeling of modified nucleosides and oligonucleotides. The transposition to radioactive chemistry is presented, and this furnishes practical access to [11C]methylated tracers for positron emission tomography imaging. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:1434193X
DOI:10.1002/ejoc.201201379