Development of a three-channel automatic climbing training system for rat rehabilitation after ischemic stroke
| العنوان: | Development of a three-channel automatic climbing training system for rat rehabilitation after ischemic stroke |
|---|---|
| المؤلفون: | Chi-Chun Chen, Ching-Ping Chang |
| المصدر: | Brazilian Journal of Medical and Biological Research v.53 n.7 2020 Brazilian Journal of Medical and Biological Research Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC Brazilian Journal of Medical and Biological Research, Volume: 53, Issue: 7, Article number: e8943, Published: 10 JUN 2020 Brazilian Journal of Medical and Biological Research, Vol 53, Iss 7 |
| بيانات النشر: | Associação Brasileira de Divulgação Científica, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Physiology, medicine.medical_treatment, Training system, Functional testing, rota-rod, Biochemistry, Brain Ischemia, 0302 clinical medicine, General Pharmacology, Toxicology and Pharmaceutics, lcsh:QH301-705.5, Stroke, inclined plane, Cerebral infarction volume, lcsh:R5-920, Rehabilitation, Ischemic stroke, Cerebral infarction, General Neuroscience, Stroke Rehabilitation, Inclined plane, Infarction, Middle Cerebral Artery, General Medicine, Climbing training system, Exercise Therapy, climbing training system, 030220 oncology & carcinogenesis, Climbing, Middle cerebral artery, cerebral infarction volume, lcsh:Medicine (General), Research Article, medicine.medical_specialty, Immunology, Biophysics, Ocean Engineering, Rota-rod, rehabilitation, 03 medical and health sciences, Physical medicine and rehabilitation, medicine.artery, ischemic stroke, medicine, Animals, cardiovascular diseases, business.industry, Overtraining, Cell Biology, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, lcsh:Biology (General), business |
| الوصف: | This paper reports the development of a three-channel automatic speed-matching climbing training system that could train three rats at the same time for rehabilitation after an ischemic stroke. An infrared (IR) remote sensor was installed at the end of each channel to monitor the real-time position of a climbing rat. This research was carried out in five stages: i) system design; ii) hardware circuit; iii) running speed control; iv) functional testing; and v) verification using an animal model of cerebral stroke. The rehabilitated group significantly outperformed the middle cerebral artery occlusion (MCAo) sedentary group in the rota-rod and inclined plate tests 21 days after a stroke. The rehabilitated group also had a cerebral infarction volume of 28.34±19.4%, far below 56.81±18.12% of the MCAo group 28 days after the stroke, validating the effectiveness of this training platform for stroke rehabilitation. The running speed of the climbing rehabilitation training platform was designed to adapt to the physical conditions of subjects, and overtraining injuries can be completely prevented accordingly. |
| وصف الملف: | text/html |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ed8f33f52d443243f68286d6115596Test http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000700608Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c6ed8f33f52d443243f68286d6115596 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |