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المصدر: PLoS ONE, Vol 16, Iss 3, p e0243645 (2021)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Physiology, Action Potentials, Biochemistry, Ion Channels, 0302 clinical medicine, Calcium Channels, N-Type, Automated patch clamp, Transient Transfection Assay, Cricetinae, Medicine and Health Sciences, Membrane Electrophysiology, Analgesics, Multidisciplinary, Chemistry, Physics, NAV1.7 Voltage-Gated Sodium Channel, Transfection, Electrophysiology, Bioassays and Physiological Analysis, Physical Sciences, 293T cells, Cell lines, Medicine, Biological cultures, Research Article, Science, Biophysics, Neurophysiology, Pain, CHO Cells, Research and Analysis Methods, Calcium Phosphate Transfection, 03 medical and health sciences, Signs and Symptoms, Cricetulus, FuGENE, Animals, Humans, Patch clamp, Molecular Biology Techniques, Molecular Biology, Ion channel, Voltage-gated ion channel, Sodium channel, Electrophysiological Techniques, Biology and Life Sciences, Proteins, High-Throughput Screening Assays, 030104 developmental biology, HEK293 Cells, Microscopy, Fluorescence, Lipofectamine, Calcium Channels, Clinical Medicine, Patch Clamp Techniques, 030217 neurology & neurosurgery, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b541cc5ff952fab70a9d767a58884ec2Test
https://doaj.org/article/f089b070a4b446cb8df4ca680b12c11cTest -
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المؤلفون: Andrea Sinz, Nina Braun, Stephan A. Pless, Christian Ihling, Søren Friis, Jacob Andersen
المصدر: Braun, N, Friis, S, Ihling, C, Sinz, A, Andersen, J & Pless, S A 2021, ' High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology ', PLOS Biology, vol. 19, no. 9, e3001321 . https://doi.org/10.1371/journal.pbio.3001321Test
PLoS Biology, Vol 19, Iss 9, p e3001321 (2021)
PLoS Biologyمصطلحات موضوعية: Atmospheric Science, Physiology, Spider Venoms, Biochemistry, Physical Chemistry, Ion Channels, Spectrum Analysis Techniques, Automated patch clamp, Animal Cells, Medicine and Health Sciences, Cross-Linking, Amino Acids, Biology (General), Receptor, Membrane Electrophysiology, Throughput (business), chemistry.chemical_classification, Fluorescence-Activated Cell Sorting, Chemistry, Physics, General Neuroscience, Methods and Resources, Transfection, Characterization (materials science), Amino acid, Electrophysiology, Bioassays and Physiological Analysis, Spectrophotometry, Physical Sciences, Cytophotometry, Cellular Types, Protons, General Agricultural and Biological Sciences, QH301-705.5, Immune Cells, Immunology, Biophysics, Antigen-Presenting Cells, Neurophysiology, Computational biology, Biology, Research and Analysis Methods, General Biochemistry, Genetics and Molecular Biology, Humans, Environmental Chemistry, Patch clamp, Molecular Biology Techniques, Molecular Biology, Ion channel, Nuclear Physics, Nucleons, Chemical Bonding, General Immunology and Microbiology, Ecology and Environmental Sciences, Electrophysiological Techniques, Biology and Life Sciences, Proteins, Cell Biology, Acid Sensing Ion Channels, HEK293 Cells, Atmospheric Chemistry, Earth Sciences, Peptides, Acid Deposition, Patch Clamp Techniques, Function (biology), Neuroscience
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47ac6c5162cc821f06ca74915038c50Test
https://doi.org/10.1101/2020.11.24.392498Test -
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المؤلفون: Abby Sewell, Glenn E. Kirsch, Caiyun Wu, Arianne L. Motter, Fedorov Nikolai, Yuri A. Kuryshev, Lucas C. Armstrong, Michael S. Orr, Zhiqi Liu, Carmine Leggett
المصدر: Slas Discovery
مصطلحات موضوعية: 0301 basic medicine, Agonist, Patch-Clamp Techniques, medicine.drug_class, Genetic Vectors, Gene Expression, Receptors, Nicotinic, Pharmacology, Nucleus accumbens, Transfection, Biochemistry, Cell Line, Analytical Chemistry, Small Molecule Libraries, Nicotine, 03 medical and health sciences, 0302 clinical medicine, Automated patch clamp, Drug Discovery, medicine, Humans, Patch clamp, nicotinic acetylcholine receptor, Cloning, Molecular, Original Research, Acetylcholine receptor, Chemistry, Electrophysiological Phenomena, High-Throughput Screening Assays, Protein Subunits, Nicotinic acetylcholine receptor, 030104 developmental biology, Nicotinic agonist, ion channel, electrophysiological screening, Molecular Medicine, automated patch clamp, Ion Channel Gating, 030217 neurology & neurosurgery, Biotechnology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1e31ebce6f9b777c6201a00c062cd3Test
https://doi.org/10.1177/2472555217696794Test -
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المصدر: Current Protocols in Pharmacology. 87
مصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Computer science, Drug discovery, General Medicine, Computational biology, Bottleneck, Electrophysiological Phenomena, High-Throughput Screening Assays, 03 medical and health sciences, Electrophysiology, 030104 developmental biology, 0302 clinical medicine, Automated patch clamp, Ion channel activity, Drug Discovery, Patch clamp, Throughput (business), 030217 neurology & neurosurgery, Ion channel
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf04d0099c93029590f96ae0c8d2036Test
https://doi.org/10.1002/cpph.69Test -
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المؤلفون: Teun P. de Boer, Alison Obergrussberger, Nadine Becker, Niels Fertig, Toon A.B. van Veen, Sonja Stoelzle-Feix, Marc A. Vos, Birgit Goversen
المصدر: Frontiers in Physiology, Vol 8 (2018)
مصطلحات موضوعية: 0301 basic medicine, lcsh:QP1-981, Physiology, Computer science, Safety pharmacology, cardiomyocyte, lcsh:Physiology, stem cell, 03 medical and health sciences, Electrophysiology, 030104 developmental biology, Clamp, Automated patch clamp, dynamic clamp, safety pharmacology, Physiology (medical), Current clamp, automated patch clamp electrophysiology, Patch clamp, Hybrid model, Ion channel, inward rectifying potassium ion channels, Biomedical engineering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c66f6050b475e17bc308f0a8cec065eTest
https://doi.org/10.3389/fphys.2017.01094Test -
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المؤلفون: Claudia Haarmann, Max Mueller, Juergen Steindl, Alison Obergrussberger, Andrea Brüggemann, Johannes Stiehler, Atsushi Ohtsuki, Niels Fertig, Nadine Becker, Marius Vogel, Tom A. Goetze, Ilka Rinke, Michael George, Takayuki Oka, Timo Stengel, Markus Rapedius
المصدر: SLAS Technology. 21:779-793
مصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Materials science, hERG, Receptors, Cell Surface, Ion Channels, Cell Line, 03 medical and health sciences, Automated patch clamp, Electronic engineering, Animals, Humans, Patch clamp, Ion channel, Automation, Laboratory, Voltage-gated ion channel, biology, Amplifier, Pipette, Robotics, High-Throughput Screening Assays, Computer Science Applications, Medical Laboratory Technology, 030104 developmental biology, biology.protein, Ligand-gated ion channel, Biomedical engineering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c31bb0ac574bd86f5dc089b001c3acTest
https://doi.org/10.1177/2211068215623209Test -
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المؤلفون: David J. Gavaghan, Ken Wang, Michael Clerx, Chon Lok Lei, Liudmila Polonchuk, Gary R. Mirams
المصدر: Biophysical Journal
مصطلحات موضوعية: Computer science, Voltage clamp, hERG, Biophysics, Gating, CHO Cells, Bayesian inference, 03 medical and health sciences, Automation, 0302 clinical medicine, Cricetulus, Single-cell analysis, Automated patch clamp, Computing & Mathematics - Applied Mathematics, Animals, Humans, Patch clamp, Throughput (business), Ion channel, 030304 developmental biology, Protocol (science), 0303 health sciences, biology, Mathematical model, business.industry, Centre for Mathematical Medicine and Biology, Bayes Theorem, Articles, Potassium channel, Ether-A-Go-Go Potassium Channels, Kinetics, biology.protein, Single-Cell Analysis, business, Biological system, 030217 neurology & neurosurgery, Communication channel
وصف الملف: PDF
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62fd21b3a91ba2c8d4b097be629ae63Test
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المؤلفون: Ingrid van Welie, Ho-Jun Suk, Edward S. Boyden
المصدر: Journal of neuroscience methods. 326
مصطلحات موضوعية: 0301 basic medicine, Automation, Laboratory, Millisecond, Patch-Clamp Techniques, Computer science, business.industry, General Neuroscience, Neurosciences, Local field potential, Automation, Electrophysiology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Automated patch clamp, Electronic engineering, Animals, Humans, Patch clamp, Whole cell, business, 030217 neurology & neurosurgery, Ion channel
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ddacc80c61a35ae9769ed54b892fddTest
https://pubmed.ncbi.nlm.nih.gov/31336060Test -
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المؤلفون: Takayuki Oka, Alison Obergrussberger, Søren Friis, Hatsue Furukawa, Nina Brinkwirth, Sonja Stoelzle-Feix, Atsushi Ohtsuki, Yuka Hasegawa, Kiyoshi Takasuna, Niels Fertig, Masafumi Doi, Nadine Becker
المصدر: Journal of Pharmacological and Toxicological Methods. 105:106884
مصطلحات موضوعية: ERG1 Potassium Channel, Patch-Clamp Techniques, hERG, Drug Evaluation, Preclinical, Dofetilide, CHO Cells, 030204 cardiovascular system & hematology, Polypropylenes, Toxicology, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Automated patch clamp, Drug Discovery, Phenethylamines, medicine, Animals, Humans, Patch clamp, Polytetrafluoroethylene, Ion channel, Pharmacology, Sulfonamides, biology, Chemistry, Drug discovery, Safety pharmacology, Reproducibility of Results, Arrhythmias, Cardiac, Cardiovascular Agents, Heart, Astemizole, Reference Standards, Benchmarking, HEK293 Cells, Calibration, biology.protein, Terfenadine, medicine.drug, Biomedical engineering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a232b0cdc1e86e3a7f7560e3afb49141Test
https://doi.org/10.1016/j.vascn.2020.106884Test -
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المؤلفون: Sonja Stölzle-Feix, Nadine Becker, Alison Obergrussberger, Andrea Brüggemann, Clemens Möller, Niels Fertig
المصدر: Channels
مصطلحات موضوعية: Patch-Clamp Techniques, Biophysics, Quantitative Structure-Activity Relationship, Nanotechnology, cardiomyocytes, Review, Biochemistry, Ion, Cell membrane, Small Molecule Libraries, action potential, Automated patch clamp, safety pharmacology, Drug Discovery, medicine, Potassium Channel Blockers, Animals, Humans, Patch clamp, Integral membrane protein, Ion channel, Chemistry, screening, ion channels, temperature, High-Throughput Screening Assays, Electrophysiology, medicine.anatomical_structure, impedance, Flux (metabolism), Sodium Channel Blockers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2d55d35260852adabdde2d95a3d964Test
http://europepmc.org/articles/PMC4850050Test