التفاصيل البيبلوغرافية
| العنوان: |
Reducing morbidity and mortality in high risk patients with statins |
| المؤلفون: |
Singh, Vibhuti, Deedwania, Prakash |
| المصدر: |
Vascular Health and Risk Management, vol Volume 5, iss 2 |
| بيانات النشر: |
eScholarship, University of California |
| سنة النشر: |
2009 |
| المجموعة: |
University of California: eScholarship |
| مصطلحات موضوعية: |
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Atherosclerosis, Clinical Research, Heart Disease - Coronary Heart Disease, Heart Disease, Cardiovascular, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Good Health and Well Being, Atorvastatin, Cardiovascular Diseases, Cholesterol, LDL, Coronary Disease, Diabetes Complications, Dose-Response Relationship, Drug, Heptanoic Acids, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Intracranial Arteriosclerosis, Kidney Failure, Chronic, Metabolic Diseases, Practice Guidelines as Topic, Pyrroles, Randomized Controlled Trials as Topic, Risk Factors, chronic kidney disease |
| جغرافية الموضوع: |
495 - 507 |
| الوصف: |
Residual coronary heart disease remains a significant problem even after adequate statin therapy for cardiovascular risk reduction as currently recommended by the Adult Treatment Panel III (ATP-III) of the National Cholesterol Education Program (NCEP). This is particularly true for the high risk patients as defined by ATP-III that includes those patients who have a greater than 20% 10-year risk of adverse cardiac events. For such patients the current goal of a low-density lipoprotein cholesterol (LDL-cholesterol) maintenance level of < or =100 mg/dL plasma appears to be suboptimal. Accumulating data from several recent randomized studies of more aggressive LDL-cholesterol reduction to levels below 70 mg/dL in the high risk patients favor acceptance of such a new lower target for LDL-cholesterol using more intensive statin therapy which would affect the treatment strategy for patients with coronary heart disease pre-percutaneous intervention, metabolic syndrome, diabetes mellitus, congestive heart failure, cerebrovascular disease and chronic kidney disease. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| العلاقة: |
qt84f3s2t4; https://escholarship.org/uc/item/84f3s2t4Test |
| الإتاحة: |
https://escholarship.org/uc/item/84f3s2t4Test |
| حقوق: |
public |
| رقم الانضمام: |
edsbas.245CF7B0 |
| قاعدة البيانات: |
BASE |
