المؤلفون: Ottman, Noora, Barrientos-Somarribas, Mauricio, Fyhrquist, Nanna, Alexander, Helen, Wisgrill, Lukas, Olah, Peter, Tsoka, Sophia, Greco, Dario, Levi-Schaffer, Francesca, Soumelis, Vassili, Schroeder, Jens M., Kere, Juha, Nestle, Frank O., Barker, Jonathan, Ranki, Annamari, Lauerma, Antti, Homey, Bernhard, Andersson, Bjorn, Alenius, Harri

المساهمون: HUMI - Human Microbiome Research, Research Programs Unit, University of Helsinki, Institute of Biotechnology, Juha Kere / Principal Investigator, HUS Inflammation Center, Department of Dermatology, Allergology and Venereology, Helsinki University Hospital Area

مصطلحات موضوعية: atopic dermatitis, inflammation, microbiome, STAPHYLOCOCCUS-AUREUS, FATTY-ACIDS, EXPRESSION, CONTAMINATION, DIVERSITY, PSORIASIS, SEVERITY, DEFECTS, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: The research has received funding from the FP7/2007-2013 (Grant 261366). The study was partially funded by the Knut and Alice Wallenberg Foundation, the Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London and King's College Hospital NHS Foundation (guysbrc-2012-1) Trust, and Dunhill Medical Trust, the Association pour la Recherche contre le Cancer (ARC), the European Research Council (Grant IT-DC 281987), Institut National de la Sante et de la Recherche Medicale (BIO2012-02 and BIO2014-08), INCA (2011-1-PL BIO-12-IC-1), Fondation ARSEP (R12023JJ), ANR (ANR-13-BSV1-0024-02, ANR-10-IDEX-0001-02 PSL* and ANR-11-LABX-0043), BIOMAP IMI2-821511; Ottman , N , Barrientos-Somarribas , M , Fyhrquist , N , Alexander , H , Wisgrill , L , Olah , P , Tsoka , S , Greco , D , Levi-Schaffer , F , Soumelis , V , Schroeder , J M , Kere , J , Nestle , F O , Barker , J , Ranki , A , Lauerma , A , Homey , B , Andersson , B & Alenius , H 2021 , ' Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites ' , Allergy : European journal of allergy and clinical immunology , vol. 76 , no. 4 , pp. 1173-1187 . https://doi.org/10.1111/all.14606Test; ORCID: /0000-0001-9195-9003/work/127003867; ORCID: /0000-0002-5078-3547/work/156156826; http://hdl.handle.net/10138/353223Test; ea42ac04-6896-45d1-a6a5-e30269719367; 000577667400001

الإتاحة: http://hdl.handle.net/10138/353223Test

المؤلفون: Fyhrquist, Nanna, Muirhead, Gareth, Prast-Nielsen, Stefanie, Jeanmougin, Marine, Olah, Peter, Skoog, Tiina, Jules-Clement, Gerome, Feld, Micha, Barrientos-Somarribas, Mauricio, Sinkko, Hanna, van den Bogaard, Ellen H., Zeeuwen, Patrick L. J. M., Rikken, Gijs, Schalkwijk, Joost, Niehues, Hanna, Däubener, Walter, Eller, Silvia Kathrin, Alexander, Helen, Pennino, Davide, Suomela, Sari, Tessas, Ioannis, Lybeck, Emilia, Baran, Anna M., Darban, Hamid, Gangwar, Roopesh Singh, Gerstel, Ulrich, Jahn, Katharina, Karisola, Piia, Yan, Lee, Hansmann, Britta, Katayama, Shintaro, Meller, Stephan, Bylesjo, Max, Hupe, Philippe, Levi-Schaffer, Francesca, Greco, Dario, Ranki, Annamari, Schröder, Jens M., Barker, Jonathan, Kere, Juha, Tsoka, Sophia, Lauerma, Antti, Soumelis, Vassili, Nestle, Frank O., Homey, Bernhard, Andersson, Björn, Alenius, Harri

المساهمون: HUMI - Human Microbiome Research, Staff Services, Department of Bacteriology and Immunology, University of Helsinki, Medicum, Department of Dermatology, Allergology and Venereology, HUS Inflammation Center, Clinicum, Institute of Biotechnology, University Management

مصطلحات موضوعية: STAPHYLOCOCCUS-AUREUS, HUMAN SKIN, INDOLEAMINE 2,3-DIOXYGENASE, DISEASE, IMMUNE, MECHANISMS, KERATINOCYTES, COLONIZATION, RECEPTOR, TISSUE, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: The authors want to thank Prof. A. Andersson (KTH Royal Institute of Technology and Science for Life Laboratory (SciLifeLab)) for providing the 16S primer designs and acknowledge support from SciLifeLab, the national infrastructure SNISS, and Uppmax for assistance in massive parallel sequencing and computational infrastructure. Technical support by D. Lundin, BILS (Bioinformatics Infrastructure for Life Sciences) and T. Keyvanfar is also acknowledged. The research has received funding from the FP7/2007-2013 (Grant 261366). The study was partially funded by the Knut and Alice Wallenberg Foundation, the Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London and King's College Hospital NHS Foundation (guysbrc-2012-1) Trust, and Dunhill Medical Trust, the Association pour la Recherche contre le Cancer (ARC), the European Research Council (Grant IT-DC 281987), Institute National de la Sante et de la Recherche Medicale (BIO2012-02 and BIO2014-08), INCA (2011-1-PL BIO-12-IC-1), Fondation ARSEP (R12023JJ), ANR (ANR-13-BSV1-0024-02, ANR-10-IDEX-0001-02 PSL*, ANR11-LABX-0043 and ZonMw MKMD grant 114021503) and BIOMAP IMI2 (Grant 821511).; Fyhrquist , N , Muirhead , G , Prast-Nielsen , S , Jeanmougin , M , Olah , P , Skoog , T , Jules-Clement , G , Feld , M , Barrientos-Somarribas , M , Sinkko , H , van den Bogaard , E H , Zeeuwen , P L J M , Rikken , G , Schalkwijk , J , Niehues , H , Däubener , W , Eller , S K , Alexander , H , Pennino , D , Suomela , S , Tessas , I , Lybeck , E , Baran , A M , Darban , H , Gangwar , R S , Gerstel , U , Jahn , K , Karisola , P , Yan , L , Hansmann , B , Katayama , S , Meller , S , Bylesjo , M , Hupe , P , Levi-Schaffer , F , Greco , D , Ranki , A , Schröder , J M , Barker , J , Kere , J , Tsoka , S , Lauerma , A , Soumelis , V , Nestle , F O , Homey , B , Andersson , B & Alenius , H 2019 , ' Microbe-host interplay in atopic dermatitis and psoriasis ' , Nature Communications , vol. 10 , 4703 . https://doi.org/10.1038/s41467-019-12253-yTest; ORCID: /0000-0001-9195-9003/work/64323791; ORCID: /0000-0003-0635-2704/work/64325852; ORCID: /0000-0002-5078-3547/work/156156820; http://hdl.handle.net/10138/306834Test; 178d8467-0fd7-4ff6-a638-d6e1435bbd8f; 000490417700015

الإتاحة: http://hdl.handle.net/10138/306834Test

المؤلفون: Alenius, Harri, Sinkko, Hanna, Moitinho-Silva, Lucas, Rodriguez, Elke, Broderick, Conor, Alexander, Helen, Reiger, Matthias, Hjelmso, Mathis Hjort, Fyhrquist, Nanna, Olah, Peter, Bryce, Paul, Smith, Catherine, Koning, Frits, Eyerich, Kilian, Greco, Dario, van den Bogaard, Ellen H., Neumann, Avidan U., Traidl-Hoffmann, Claudia, Homey, Bernhard, Flohr, Carsten, Bonnelykke, Klaus, Stokholm, Jakob, Weidinger, Stephan

المساهمون: HUMI - Human Microbiome Research, Faculty of Medicine, Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE

مصطلحات موضوعية: atopic dermatitis, biomarkers, microbiome, psoriasis, STAPHYLOCOCCUS-AUREUS COLONIZATION, CHRONIC PLAQUE PSORIASIS, ATOPIC-DERMATITIS, GUT MICROBIOTA, GLOBAL BURDEN, YOUNG INFANT, EARLY-LIFE, ECZEMA, ASSOCIATION, PREVALENCE, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: The research has received funding from the FP7 (MAARS-Grant 261366) and IMI2 (BIOMAP-Grant 821511).; Alenius , H , Sinkko , H , Moitinho-Silva , L , Rodriguez , E , Broderick , C , Alexander , H , Reiger , M , Hjelmso , M H , Fyhrquist , N , Olah , P , Bryce , P , Smith , C , Koning , F , Eyerich , K , Greco , D , van den Bogaard , E H , Neumann , A U , Traidl-Hoffmann , C , Homey , B , Flohr , C , Bonnelykke , K , Stokholm , J & Weidinger , S 2021 , ' The power and potential of BIOMAP to elucidate host-microbiome interplay in skin inflammatory diseases ' , Experimental Dermatology , vol. 30 , no. 10 , pp. 1517-1531 . https://doi.org/10.1111/exd.14446Test; ORCID: /0000-0001-9195-9003/work/101176795; 5880114c-1fab-4dcf-8a13-e47f750bb954; http://hdl.handle.net/10138/335076Test; 000687548700001

الإتاحة: http://hdl.handle.net/10138/335076Test