نتائج البحث - "Joshua R. Huot"

1

ACVR2B antagonism as a countermeasure to multi‐organ perturbations in metastatic colorectal cancer cachexia

المؤلفون: Fabrizio Pin, Andrea Bonetto, Leah J. Novinger, Monte S. Willis, Joshua R. Huot, Ashok Narasimhan, Austin S Keith, Teresa A. Zimmers

المصدر: Journal of Cachexia, Sarcopenia and Muscle

مصطلحات موضوعية: Male, 0301 basic medicine, Cardiac function curve, medicine.medical_specialty, Cachexia, Skeletal muscle, Adipose tissue, Liver metastases, Mice, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Animals, Orthopedics and Sports Medicine, Bone, Muscle, Skeletal, Wasting, Ejection fraction, business.industry, Liver Neoplasms, Cardiac muscle, Cancer, Heart, Original Articles, medicine.disease, Colorectal cancer, Disease Models, Animal, Activin signalling, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, 030220 oncology & carcinogenesis, Original Article, medicine.symptom, Colorectal Neoplasms, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b6050ae4d294bc7aff79e56474f1cdTest
https://doi.org/10.1002/jcsm.12642Test

2

MC38 Tumors Induce Musculoskeletal Defects in Colorectal Cancer

المؤلفون: Fabrizio Pin, Joshua R. Huot, Andrea Bonetto, Alyson L. Essex

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1486, p 1486 (2021)

مصطلحات موضوعية: Male, Colorectal cancer, Muscle Fibers, Skeletal, Gastroenterology, bone, lcsh:Chemistry, Mice, Subcutaneous Tissue, Femur, Young adult, Wasting, lcsh:QH301-705.5, Spectroscopy, Muscle Weakness, Liver Neoplasms, digestive, oral, and skin physiology, General Medicine, musculoskeletal system, Computer Science Applications, Muscular Atrophy, medicine.anatomical_structure, Disease Progression, medicine.symptom, Colorectal Neoplasms, hormones, hormone substitutes, and hormone antagonists, Muscle Contraction, STAT3 Transcription Factor, medicine.medical_specialty, colorectal cancer, Adenocarcinoma, cachexia, Article, Catalysis, Cachexia, Inorganic Chemistry, Contractility, Atrophy, Cell Line, Tumor, Internal medicine, medicine, Animals, Physical and Theoretical Chemistry, skeletal muscle, Muscle, Skeletal, Molecular Biology, neoplasms, business.industry, Organic Chemistry, Skeletal muscle, X-Ray Microtomography, medicine.disease, digestive system diseases, Blockade, Mice, Inbred C57BL, lcsh:Biology (General), lcsh:QD1-999, business, liver metastases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0dd57bf24453f7ec34f115eaa54579Test

3

PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia

المؤلفون: Marion E. Couch, Andrea Bonetto, Joshua R. Huot, Leah J. Novinger, Thomas M. O’Connell, Fabrizio Pin, Robert A. Harris

المصدر: The FASEB Journal. 33:7778-7790

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6d9cb764e9d78940286b810086b8a7Test
https://doi.org/10.1096/fj.201802799rTest

4

Treatment With Treprostinil and Metformin Normalizes Hyperglycemia and Improves Cardiac Function in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

المصدر: Arterioscler Thromb Vasc Biol
Arteriosclerosis, thrombosis, and vascular biology, vol 40, iss 6

مصطلحات موضوعية: Leptin, 0301 basic medicine, Male, Cardiorespiratory Medicine and Haematology, 030204 cardiovascular system & hematology, AMP-Activated Protein Kinases, Inbred C57BL, Cardiovascular, Mice, 0302 clinical medicine, Receptors, Lung, Metabolic Syndrome, Diabetes, Heart, Pulmonary, Metformin, Heart Disease, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Hypertension, Cardiology, Receptors, Leptin, Left heart disease, Development of treatments and therapeutic interventions, Cardiology and Cardiovascular Medicine, medicine.drug, Cardiac function curve, medicine.medical_specialty, Hypertension, Pulmonary, Clinical Sciences, Diet, High-Fat, metabolic syndrome, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, Animals, Hypoglycemic Agents, Obesity, Metabolic and endocrine, Antihypertensive Agents, Nutrition, Heart Failure, business.industry, treprostinil, Evaluation of treatments and therapeutic interventions, Stroke Volume, medicine.disease, Pulmonary hypertension, Epoprostenol, Diet, Rats, Mice, Inbred C57BL, High-Fat, 030104 developmental biology, glucose intolerance, Cardiovascular System & Hematology, Hyperglycemia, Metabolic syndrome, Insulin Resistance, Heart failure with preserved ejection fraction, business, Treprostinil

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a606dca2088db7c61a4384a37d651fTest
https://pubmed.ncbi.nlm.nih.gov/32966132Test

5

Bisphosphonate Treatment Ameliorates Chemotherapy-Induced Bone and Muscle Abnormalities in Young Mice

المؤلفون: Alyson L. Essex, Fabrizio Pin, Joshua R. Huot, Lynda F. Bonewald, Lilian I. Plotkin, Andrea Bonetto

المصدر: Frontiers in Endocrinology, Vol 10 (2019)
Frontiers in Endocrinology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8f6b5f3a4c7fd57137bc5a29cbe374Test
https://www.frontiersin.org/article/10.3389/fendo.2019.00809/fullTest

6

HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia

المؤلفون: Joshua R. Huot, Andrea Bonetto, Fabrizio Pin, Leah J. Novinger

المصدر: Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 13, Iss 1 (2020)

مصطلحات موضوعية: Male, Cachexia, Colorectal cancer, Medicine (miscellaneous), lcsh:Medicine, Skeletal muscle, STAT3, Mice, Liver metastases, 0302 clinical medicine, Immunology and Microbiology (miscellaneous), Wasting, 0303 health sciences, biology, Myogenesis, Liver Neoplasms, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cytokines, medicine.symptom, Colorectal Neoplasms, lcsh:RB1-214, Research Article, STAT3 Transcription Factor, medicine.medical_specialty, Neuroscience (miscellaneous), HCT116, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Atrophy, Internal medicine, medicine, lcsh:Pathology, Animals, Humans, Muscle, Skeletal, neoplasms, 030304 developmental biology, business.industry, Interleukin-6, Wasting Syndrome, lcsh:R, medicine.disease, HCT116 Cells, Protein ubiquitination, digestive system diseases, Mitochondria, Muscle, Disease Models, Animal, Endocrinology, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349243284d3324470b591013a4bf4dc2Test
https://pubmed.ncbi.nlm.nih.gov/31915140Test

7

Abstract 969: PKC-theta modulates myosteatosis, muscle function, atrophy, and survival in murine pancreatic ductal adenocarcinoma

المؤلفون: Teresa A. Zimmers, Andrea Bonetto, Joseph E. Rupert, Joshua R. Huot, Daenique H A Jengelley, Ashok Narasimhan

المصدر: Cancer Research. 81:969-969

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Myogenesis, Chemistry, Adipose tissue, Inflammation, medicine.disease, Muscle atrophy, Cachexia, Endocrinology, Atrophy, Oncology, Internal medicine, medicine, Muscular dystrophy, medicine.symptom, Protein kinase C

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0b5e0e3780df4bb53d8a6238e034b409Test
https://doi.org/10.1158/1538-7445.am2021-969Test

8

Chronic Treatment with Multi-Kinase Inhibitors Causes Differential Toxicities on Skeletal and Cardiac Muscles

المؤلفون: Lilian I. Plotkin, Maya Gutierrez, David L. Waning, Alyson L. Essex, Rafael Barreto, Andrea Bonetto, Meijing Wang, Joshua R. Huot

المصدر: Cancers
Cancers, Vol 11, Iss 4, p 571 (2019)
Volume 11
Issue 4

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_specialty, chemotherapy, lcsh:RC254-282, Article, Cachexia, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Regorafenib, Internal medicine, medicine, PI3K/AKT/mTOR pathway, business.industry, Autophagy, Cardiac muscle, Skeletal muscle, Muscle weakness, cardiac cachexia, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Muscle atrophy, 3. Good health, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, skeletal muscle wasting, sorafenib, regorafenib, medicine.symptom, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c44ce6b7d74c50c690cf29a8c9a0bfcTest
http://europepmc.org/articles/PMC6520777Test

9

Phytoecdysteroids Do Not Have Anabolic Effects in Skeletal Muscle in Sedentary Aging Mice

المؤلفون: Marcus M. Lawrence, David C. Nieman, Kevin A. Zwetsloot, Mary Ann Lila, Joshua R. Huot, Mary H. Grace, Chase A. Sherman, R. Andrew Shanely, Vladimir Badmaev, Susan T Arthur

المصدر: International Journal of Environmental Research and Public Health
Volume 18
Issue 2
International Journal of Environmental Research and Public Health, Vol 18, Iss 370, p 370 (2021)

مصطلحات موضوعية: Male, Aging, medicine.medical_specialty, Anabolism, Health, Toxicology and Mutagenesis, Phytoecdysteroid, lcsh:Medicine, Myostatin, Article, Muscle hypertrophy, atrogenes, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Anabolic Agents, 0302 clinical medicine, Internal medicine, medicine, Animals, skeletal muscle, Muscle, Skeletal, p70S6K, Protein kinase B, 030304 developmental biology, 0303 health sciences, biology, Akt, lcsh:R, Public Health, Environmental and Occupational Health, Skeletal muscle, Rats, Mice, Inbred C57BL, Endocrinology, medicine.anatomical_structure, biology.protein, Phosphorylation, 20-hydroxyecdysone, hypertrophy, C2C12, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622d1e7db406876663dd8735b0b5c110Test
https://doi.org/10.3390/ijerph18020370Test

10

Altered left ventricular performance in aging physically active mice with an ankle sprain injury

المؤلفون: Joseph S. Marino, Erik A. Wikstrom, Tricia Hubbard-Turner, Sophie Guderian, Joshua R. Huot, Bailey Peck, Susan T Arthur, Michael J. Turner

المصدر: AGE. 38

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739aef6b244aa2568c07de99d5a65859Test
https://doi.org/10.1007/s11357-016-9877-2Test

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