دورية أكاديمية
A One-Day Prospective National Observational Study on Sedation-Analgesia of Patients with Brain Injury in French Intensive Care Units: The SEDA-BIP-ICU (Sedation-Analgesia in Brain Injury Patient in ICU) Study
| العنوان: | A One-Day Prospective National Observational Study on Sedation-Analgesia of Patients with Brain Injury in French Intensive Care Units: The SEDA-BIP-ICU (Sedation-Analgesia in Brain Injury Patient in ICU) Study |
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| المؤلفون: | Poignant, Simon, Vigué, Bernard, Balram, Patricia, Biais, Mathieu, Carillon, Romain, Cottenceau, Vincent, Dahyot-Fizelier, Claire, Degos, Vincent, Geeraerts, Thomas, Jeanjean, Patrick, Vega, Emmanuel, Lasocki, Sigismond, Espitalier, Fabien, Laffon, Marc, Gay, Samuel, de Courson, Hugues, Huet, Olivier, Laquay, Nathalie, Chabanne, Russel, Nadji, Abdelouaid, Francony, Gilles, Payen, Jean François, Abgrall, Gwenole, Challard, Kevin, Perrigault, Pierre-François, Audibert, Gérard, Lakhal, Karim, Quintard, Hervé, Couadeau, Emmanuel, Azougagh, Khalid, Barbier, François, Engrand, Nicolas, de Forges, François Lemoyne, Seguin, Philippe, Asmolov, Romain, Ocquidant, Philippe, Morel, Jérôme, Cohen, Benjamin, Ehrmann, Stephan, Elaroussi, Djilali |
| المساهمون: | Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hôpital Pellegrin, CHU Bordeaux-Groupe hospitalier Pellegrin, Hospices Civils de Lyon (HCL), CHU Bordeaux, Centre hospitalier universitaire de Poitiers = Poitiers University Hospital (CHU de Poitiers La Milétrie ), Pharmacologie des anti-infectieux et antibiorésistance U 1070 (PHAR2 Poitiers ), Université de Poitiers = University of Poitiers (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Poitiers - Faculté de Médecine et de Pharmacie, Université de Poitiers = University of Poitiers (UP), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Pôle Anesthésie Réanimation CHU de Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CHU Amiens-Picardie, Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM) |
| المصدر: | ISSN: 1541-6933. |
| بيانات النشر: | HAL CCSD Springer |
| سنة النشر: | 2022 |
| المجموعة: | Université de Poitiers: Publications de nos chercheurs.ses (HAL) |
| مصطلحات موضوعية: | Brain injury, Intensive care unit, Sedation-analgesia, [SDV]Life Sciences [q-bio], [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences |
| الوصف: | International audience ; Background: Sedation/analgesia is a daily challenge faced by intensivists managing patients with brain injury (BI) in intensive care units (ICUs). The optimization of sedation in patients with BI presents particular challenges. A choice must be made between the potential benefit of a rapid clinical evaluation and the potential exacerbation of intracranial hypertension in patients with impaired cerebral compliance. In the ICU, a pragmatic approach to the use of sedation/analgesia, including the optimal titration, management of multiple drugs, and use of any type of brain monitor, is needed. Our research question was as follows: the aim of the study is to identify what is the current daily practice regarding sedation/analgesia in the management of patients with BI in the ICU in France?Methods: This study was composed of two parts. The first part was a descriptive survey of sedation practices and characteristics in 30 French ICUs and 27 academic hospitals specializing in care for patients with BI. This first step validates ICU participation in data collection regarding sedation-analgesia practices. The second part was a 1-day prospective cross-sectional snapshot of all characteristics and prescriptions of patients with BI.Results: On the study day, among the 246 patients with BI, 106 (43%) had a brain monitoring device and 74 patients (30%) were sedated. Thirty-nine of the sedated patients (53%) suffered from intracranial hypertension, 14 patients (19%) suffered from agitation and delirium, and 7 patients (9%) were sedated because of respiratory failure. Fourteen patients (19%) no longer had a formal indication for sedation. In 60% of the sedated patients, the sedatives were titrated by nurses based on sedation scales. The Richmond Agitation Sedation Scale was used in 80% of the patients, and the Behavioral Pain Scale was used in 92%. The common sedatives and opioids used were midazolam (58.1%), propofol (40.5%), and sufentanil (67.5%). The cerebral monitoring devices available in the ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-03623096; https://hal.science/hal-03623096Test |
| DOI: | 10.1007/s12028-021-01298-x |
| الإتاحة: | https://doi.org/10.1007/s12028-021-01298-xTest https://hal.science/hal-03623096Test |
| رقم الانضمام: | edsbas.D841E751 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s12028-021-01298-x |
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