Prognosis of Prolonged Intensive Care Unit Stay After Aortic Valve Replacement for Severe Aortic Stenosis in Octogenarians

التفاصيل البيبلوغرافية
العنوان: Prognosis of Prolonged Intensive Care Unit Stay After Aortic Valve Replacement for Severe Aortic Stenosis in Octogenarians
المؤلفون: Ivan Philip, Sophie Provenchère, Philippe Montravers, Sebastien Tanaka, Pascal Augustin, Vibol Chhor, Hassan Ibrahim, Nicolas Allou, Marie-Pierre Dilly, Darko Arnaudovski
المصدر: Survey of Anesthesiology. 61:31
بيانات النشر: Ovid Technologies (Wolters Kluwer Health), 2017.
سنة النشر: 2017
مصطلحات موضوعية: Male, medicine.medical_specialty, Critical Care, 030204 cardiovascular system & hematology, Severity of Illness Index, law.invention, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Aortic valve replacement, Risk Factors, law, Intensive care, medicine, Humans, Prospective Studies, Intensive care medicine, Geriatric Assessment, Aged, 80 and over, Heart Valve Prosthesis Implantation, business.industry, Mortality rate, Aortic Valve Stenosis, Odds ratio, Length of Stay, Prognosis, medicine.disease, Intensive care unit, Confidence interval, Surgery, Cardiac surgery, Intensive Care Units, Stenosis, Anesthesiology and Pain Medicine, 030228 respiratory system, Aortic Valve, Heart Valve Prosthesis, Emergency medicine, Female, France, Cardiology and Cardiovascular Medicine, business
الوصف: Objectives Octogenarians considered for cardiac surgery encounter more complications than other patients. Postoperative complications raise the question of continuation of high-cost care for patients with limited life expectancy. Duration of hospitalization in intensive care after cardiac surgery may differ between octogenarians and other patients. The objectives were evaluating the mortality rate of octogenarians experiencing prolonged hospitalization in intensive care and defining the best cut-off for prolonged intensive care unit length of stay. Design A single-center observational study. Setting A postoperative surgical intensive care unit in a tertiary teaching hospital in Paris, France. Participants All consecutive patients older than 80 years considered for aortic valve replacement for aortic stenosis were included. Measurements and Main Results Mortality rate was determined among patients experiencing prolonged stay in intensive care with organ failure and without organ failure. An ROC curve determined the optimal cut-off defining prolonged hospitalization in intensive care according to the occurrence of postoperative complications. Multivariate analysis determined risk factors for early death or prolonged intensive care stay. The optimal cut-off defining prolonged intensive care unit length of stay was 4 days. Low ventricular ejection fraction (odds ratio [OR] = 0.95; 95% confidence interval [CI] 0.96-0.83; p = 0.0016), coronary disease (OR = 2.34; 95% CI 1.19-4.85; p = 0.014), and need for catecholamine (OR = 2.79; 95% CI 1.33-5.88; p = 0.0068) were associated with eventful postoperative course. There was not a hospitalization duration beyond which the prognosis significantly worsened. Conclusions Prolonged length of stay in ICU without organ failure is not associated with increased mortality. No specific duration of hospitalization in intensive care was associated with increased mortality. Continuation of care should be discussed on an individual basis.
تدمد: 0039-6206
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adeb870a3fdddded1a86353bade42241Test
https://doi.org/10.1097/sa.0000000000000294Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....adeb870a3fdddded1a86353bade42241
قاعدة البيانات: OpenAIRE