COVID-19 Neurological Manifestations and Underlying Mechanisms: A Scoping Review
| العنوان: | COVID-19 Neurological Manifestations and Underlying Mechanisms: A Scoping Review |
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| المؤلفون: | Angela Wenting, Angélique Gruters, Yindee van Os, Sonja Verstraeten, Susanne Valentijn, Rudolf Ponds, Marjolein de Vugt |
| المصدر: | Frontiers in Psychiatry, Vol 11 (2020) Frontiers in Psychiatry |
| بيانات النشر: | Frontiers Media S.A., 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), lcsh:RC435-571, Review, CINAHL, PsycINFO, SARS-COV-2, CORONAVIRUS, Virus diseases, cognitive, 03 medical and health sciences, 0302 clinical medicine, lcsh:Psychiatry, Medicine, Intensive care medicine, Primary problem, Corona Virus Disease 2019, Psychiatry, COMPLICATIONS, neurological, business.industry, Cognition, neurotropic, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, VIRUS, Observational study, scoping review, business, 030217 neurology & neurosurgery, Encephalitis |
| الوصف: | Background: In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvement and cognitive consequences. Methods: A scoping review was conducted with multiple searches in PubMed, PsycInfo and CINAHL databases. Full text articles in English were included if they involved humans with COVID-19. The search was updated twice, the latest on 19 May 2020. Results: After screening 266 records and cross referencing, 85 articles were included. The articles were case studies, opinion papers, letters to editors and a few observational studies. No articles were found regarding cognitive consequences in COVID-19 patients. All reported on neurological manifestations and/or underlying mechanisms of CNS involvement in COVID-19. Conclusion: Neurological manifestations of COVID-19 vary from mild (e.g. loss of taste and smell, dizziness, headache) to severe (e.g. ischemic stroke, encephalitis). Underlying pathways are suggested to be both indirect (as a result of thrombotic complication, inflammatory consequences, hypoxia, blood pressure dysregulation), and direct (neurotropic properties of the virus). Since most articles were opinion papers and no studies have been conducted on cognitive consequences, further research is warranted. |
| اللغة: | English |
| تدمد: | 1664-0640 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff98fde103d8bb7c26a984e3ed533caTest https://www.frontiersin.org/article/10.3389/fpsyt.2020.00860/fullTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....eff98fde103d8bb7c26a984e3ed533ca |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16640640 |
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