المؤلفون: Vecchio, Federica, Lo Buono, Nicola, Stabilini, Angela, Nigi, Laura, Dufort, Matthew J, Geyer, Susan, Rancoita, Paola Maria, Cugnata, Federica, Mandelli, Alessandra, Valle, Andrea, Leete, Pia, Mancarella, Francesca, Linsley, Peter S, Krogvold, Lars, Herold, Kevan C, Elding Larsson, Helena, Richardson, Sarah J, Morgan, Noel G, Dahl-Jørgensen, Knut, Sebastiani, Guido, Dotta, Francesco, Bosi, Emanuele, Battaglia, Manuela

المصدر: JCI Insight EXODIAB: Excellence of Diabetes Research in Sweden. 3(18)

مصطلحات موضوعية: Autoantibodies, Autoimmune Diseases, Diabetes Mellitus, Type 1/immunology, Extracellular Traps/immunology, Gene Expression, Gene Expression Profiling, Humans, Immunity, Innate, Insulin-Secreting Cells, Interferons/genetics, Neutrophils/immunology, Pancreas/immunology, Transcriptome, Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes

الوصول الحر: https://lup.lub.lu.se/record/f6a89aed-70dd-40dd-968d-6acaa45b676bTest
http://dx.doi.org/10.1172/jci.insight.122146Test

المؤلفون: Wakeling, Matthew N., Owens, Nick D. L., Hopkinson, Jessica R., Johnson, Matthew B., Houghton, Jayne A. L., Dastamani, Antonia, Flaxman, Christine S., Wyatt, Rebecca C., Hewat, Thomas I., Hopkins, Jasmin J., Laver, Thomas W., van Heugten, Rachel, Weedon, Michael N., De Franco, Elisa, Patel, Kashyap A., Ellard, Sian, Morgan, Noel G., Cheesman, Edmund, Banerjee, Indraneel, Hattersley, Andrew T., Dunne, Mark J., Richardson, Sarah J., Flanagan, Sarah E.

مصطلحات موضوعية: congenital hyperinsulinism, HK1 gene, Hexokinase, Insulin-Secreting Cells, Insulin Secretion, Genetics, Humans, Congenital Hyperinsulinism, Regulatory Sequences, Nucleic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6a5475606b98947adba6c9d453526cTest
https://doi.org/10.1038/s41588-022-01204-xTest

المؤلفون: Rodriguez-Calvo, Teresa, Chen, Yi-Chun, Verchere, C. Bruce, Haataja, Leena, Arvan, Peter, Leete, Pia, Richardson, Sarah J., Morgan, Noel G., Qian, Wei-Jun, Pugliese, Alberto, Atkinson, Mark, Evans-Molina, Carmella, Sims, Emily K.

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Type 1 diabetes mellitus, Insulin-secreting cells, Proinsulin

وصف الملف: application/pdf

العلاقة: Diabetes; Rodriguez-Calvo T, Chen YC, Verchere CB, et al. Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes. Diabetes. 2021;70(5):1038-1050. doi:10.2337/dbi20-0034; https://hdl.handle.net/1805/33988Test

الإتاحة: https://doi.org/10.2337/dbi20-0034Test
https://hdl.handle.net/1805/33988Test

المؤلفون: Russell, Mark A., Cooper, Angela C., Dhayal, S, Morgan, Noel G.

مصطلحات موضوعية: Janus kinase, STAT3, STAT6, interleukin-13, interleukin-6, pancreatic β-cells, Animals, Cell Line, Cell Survival, Humans, Insulin-Secreting Cells, Islets of Langerhans, Janus Kinases, Phosphorylation, Protein Processing, Post-Translational, Rats, Receptors, STAT Transcription Factors, STAT3 Transcription Factor, STAT6 Transcription Factor, Signal Transduction, Tissue Culture Techniques, Up-Regulation

العلاقة: http://www.ncbi.nlm.nih.gov/pubmed/23510983Test; Vol. 5 (2), pp. 95 - 105; 261441; http://hdl.handle.net/10871/18085Test; Islets

الإتاحة: https://doi.org/10.4161/isl.24249Test
http://hdl.handle.net/10871/18085Test

المؤلفون: Richardson, Sarah J, Morgan, Noel G

المصدر: Current Opinion in Pharmacology

مصطلحات موضوعية: Blood Glucose, Antiviral Agents, Article, Diabetes Mellitus, Type 1, Risk Factors, Drug Design, Insulin-Secreting Cells, Host-Pathogen Interactions, Enterovirus Infections, Animals, Humans, Hypoglycemic Agents, Biomarkers, ComputingMethodologies_COMPUTERGRAPHICS, Enterovirus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::21b7f562205e0682bff3dc186848a4a3Test
http://europepmc.org/articles/PMC6294842Test

المؤلفون: Willcox, A, Richardson, Sarah J., Bone, AJ, Foulis, Alan K., Morgan, Noel G.

مصطلحات موضوعية: Adolescent, Adult, Capsid Proteins, Cell Proliferation, Child, Diabetes Mellitus, Type 1, Enterovirus, Female, Humans, Immunohistochemistry, Infant, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Ki-67 Antigen, Male, Retrospective Studies, Virus Replication, Young Adult

العلاقة: http://www.ncbi.nlm.nih.gov/pubmed/21597997Test; Vol. 54, pp. 2417 - 2420; http://hdl.handle.net/10871/18088Test; Diabetologia

الإتاحة: https://doi.org/10.1007/s00125-011-2192-7Test
http://hdl.handle.net/10871/18088Test

المؤلفون: Reers, Christina, Hauge-Evans, Astrid C, Morgan, Noel G, Wilcox, Abby, Persaud, Shanta J, Jones, Peter M

المصدر: Reers , C , Hauge-Evans , A C , Morgan , N G , Wilcox , A , Persaud , S J & Jones , P M 2011 , ' Down-regulation of proliferation does not affect the secretory function of transformed β-cell lines regardless of their anatomical configuration ' , ISLETS , vol. 3 , no. 3 , pp. 80-8 .

مصطلحات موضوعية: Animals, Cell Growth Processes, Cell Line, Transformed, Down-Regulation, Doxycycline, Histocytochemistry, Insulin, Insulin-Secreting Cells, Mice, Mitomycin, Nucleic Acid Synthesis Inhibitors

الإتاحة: https://pure.roehampton.ac.uk/portal/en/publications/f82f7cd0-b42b-4665-8a42-1d67fccdf32fTest

المؤلفون: Willcox, A, Richardson, Sarah J., Bone, AJ, Foulis, Alan K., Morgan, Noel G.

مصطلحات موضوعية: Adolescent, Adult, Cell Cycle Proteins, Cell Proliferation, Child, Preschool, Diabetes Mellitus, Type 1, Female, Glucagon-Secreting Cells, Humans, Immunohistochemistry, Infant, Insulin-Secreting Cells, Ki-67 Antigen, Male, Nuclear Proteins, Pancreas, Young Adult

العلاقة: http://www.ncbi.nlm.nih.gov/pubmed/20532863Test; http://link.springer.com/article/10.1007%2Fs00125-010-1817-6Test; Diabetologia, 2010, Vol. 53, Issue 9, pp. 2020 - 2028; http://hdl.handle.net/10871/13815Test; Diabetologia

الإتاحة: https://doi.org/10.1007/s00125-010-1817-6Test
http://hdl.handle.net/10871/13815Test

المؤلفون: Dhayal, Shalinee, Morgan, Noel G

مصطلحات موضوعية: Cell Death, Dose-Response Relationship, Drug, Cell Survival, Serum Albumin, Bovine, Arachidonic Acids, Research Papers, Dinoprostone, Cell Line, Rats, Cytoprotection, Insulin-Secreting Cells, Insulin Secretion, Fatty Acids, Unsaturated, Animals, Insulin, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::b19aba6dab10523bb0be6da0940eac7eTest
https://europepmc.org/articles/PMC3058166Test/

المؤلفون: Jay M. Sosenko, D. J. Becker, Kevan C. Herold, E. Leschek, James W. Thomas, Francesco Dotta, Jeffrey L. Mahon, K. Nanto-Salonen, Diane K. Wherrett, Lisa M. Spain, Andrew Muir, Polly J. Bingley, Massimo Trucco, Jeffrey P. Krischer, S. E. Gitelman, Alessandra Mandelli, Mark S. Anderson, Sarah J. Richardson, Peter S. Linsley, Riccardo Bonfanti, Eleonora Bianconi, George S. Eisenbarth, M. Siegelman, J. Peyman, Angela Stabilini, M. Redondo, Bernhard J. Hering, Richard A. Insel, Maurizio De Pellegrin, Franco Meschi, Francesca Ragogna, Mark A. Clements, Lars Krogvold, Mark Peakman, Alberto Pugliese, J. Blum, William E. Russell, P. Chase, Pia Leete, Anette-Gabriele Ziegler, Mark A. Atkinson, Jane H. Buckner, Andrea Rigamonti, Tihamer Orban, Laura Nigi, Philip Raskin, Guido Sebastiani, Louis H. Philipson, Linda A. DiMeglio, Clara Bonura, Manuela Battaglia, Jay S. Skyler, David A. Baidal, Giulio Frontino, Emanuele Bosi, Matthew J. Dufort, Andrea Valle, William E. Winter, Peter A. Gottlieb, C. G. Fathman, Helena Elding Larsson, Robin Goland, Michael J. Clare-Salzler, M. G. Roncarolo, Raphael Clynes, Peter A. Antinozzi, Andrea K. Steck, Mikael Knip, Olli Simell, R. Parkman, Bart O. Roep, Desmond A. Schatz, Henry Rodriguez, Nicola Lo Buono, John M. Wentworth, Andrea Laurenzi, Francesca Mancarella, P. Savage, Jennifer B. Marks, G. Grave, Paola M.V. Rancoita, Federica Vecchio, Åke Lernmark, Darrell M. Wilson, Noel G. Morgan, Thomas W.H. Kay, Francine R. Kaufman, Federica Cugnata, Christophe Benoist, Susan Geyer, Peter G. Colman, Mark D. Pescovitz, Robert S. Sherwin, Gerald T. Nepom, John E. Wagner, Antoinette Moran, Knut Dahl-Jørgensen, Jerry P. Palmer, Kasia Bourcier, Wayne V. Moore, Carla J. Greenbaum, Pauline Grogan

المساهمون: Vecchio, Federica, Lo Buono, Nicola, Stabilini, Angela, Nigi, Laura, Dufort, Matthew J., Geyer, Susan, Rancoita, Paola Maria, Cugnata, Federica, Mandelli, Alessandra, Valle, Andrea, Leete, Pia, Mancarella, Francesca, Linsley, Peter S., Krogvold, Lar, Herold, Kevan C., Elding Larsson, Helena, Richardson, Sarah J., Morgan, Noel G., Dahl-Jørgensen, Knut, Sebastiani, Guido, Dotta, Francesco, Bosi, Emanuele, Battaglia, Manuela

مصطلحات موضوعية: 0301 basic medicine, endocrine system diseases, Neutrophils, Immunology, Gene Expression, Autoimmunity, Disease, Immunofluorescence, medicine.disease_cause, Extracellular Traps, Autoimmune Diseases, 03 medical and health sciences, Insulin-Secreting Cells, Diabetes mellitus, Autoimmune disease, medicine, Humans, Pancreas, Autoantibodies, Innate immunity, Type 1 diabetes, Innate immune system, medicine.diagnostic_test, business.industry, Gene Expression Profiling, General Medicine, Neutrophil extracellular traps, medicine.disease, Immunity, Innate, 3. Good health, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, Interferons, Clinical Medicine, Transcriptome, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee5d8b12a49d70a6a58dc2174c69799Test