دورية أكاديمية

Menstrual Cycle, Glucose Control and Insulin Sensitivity in Type 1 Diabetes: A Systematic Review

التفاصيل البيبلوغرافية
العنوان: Menstrual Cycle, Glucose Control and Insulin Sensitivity in Type 1 Diabetes: A Systematic Review
المؤلفون: Elena Gamarra, Pierpaolo Trimboli
المصدر: Journal of Personalized Medicine; Volume 13; Issue 2; Pages: 374
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2023
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: menstrual cycle, type 1 diabetes mellitus, continuous glucose monitoring, glucose metrics, insulin sensitivity
الوصف: The correlation between the menstrual cycle and glucose control in type 1 diabetes has been the focus of several studies since the 1920s, but a few critical aspects made it particularly challenging to reach conclusive evidence. The aim of this systematic review is to reveal more solid information about the impact of the menstrual cycle on glycaemic outcomes and insulin sensitivity in type 1 diabetes and highlight the less researched areas. The literature was searched by two authors independently using PubMed/MEDLINE, Embase and Scopus (last search on 2 November 2022). The retrieved data did not allow us to perform a meta-analysis. We included 14 studies published between 1990 and 2022, with sample sizes from 4 to 124 patients. We found a wide heterogeneity in the definition of the menstrual cycle phases, glucose metrics, techniques for determining insulin sensitivity, hormonal assessment and other interfering factors considered, with an overall high risk of bias. There is no conclusive evidence, and published data do not allow us to achieve quantitative results. In a subset of patients, a possible worsening of insulin sensitivity and hyperglycaemia in the luteal phase could be observed. From the clinical standpoint, a cautious strategy based on patient-specific patterns can be considered until new, solid evidence is obtained.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
العلاقة: Sex, Gender and Hormone Based Medicine; https://dx.doi.org/10.3390/jpm13020374Test
DOI: 10.3390/jpm13020374
الإتاحة: https://doi.org/10.3390/jpm13020374Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.C3A0B4CC
قاعدة البيانات: BASE