Plasmids and the spread of antibiotic resistance
| العنوان: | Plasmids and the spread of antibiotic resistance |
|---|---|
| المؤلفون: | Christopher M. Thomas, Claire E Miller, Alessandro Lazdins |
| المصدر: | The Biochemist. 37:12-17 |
| بيانات النشر: | Portland Press Ltd., 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Transposable element, Genetics, Antibiotic resistance, Plasmid, Insertion sequence, Biology, General Biochemistry, Genetics and Molecular Biology |
| الوصف: | The term plasmid was first coined in 1952 by Joshua Lederberg to encompass all extra-chromosomal hereditary determinants1. One of the first plasmids discovered allowed the movement of genes from one bacterial strain to another, creating a sort of ‘bacterial sex’ or ‘fertility’ so that the entity responsible was called the ‘fertility factor’ or F-factor2. Plasmids carrying antibiotic resistance were soon discovered and became a topic of intense research which contributed to the development of cloning vectors that underpinned the gene cloning revolution in the 1970s. Although the problems created by plasmids were clear to many from the beginning, we do not yet have ways to control their acquisition and spread of resistance. |
| تدمد: | 1740-1194 0954-982X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::98303b840c4248d954756fa2fd1c6ec9Test https://doi.org/10.1042/bio03703012Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........98303b840c4248d954756fa2fd1c6ec9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17401194 0954982X |
|---|