المؤلفون: Yasir I. B. Ahmed, Hind S. Yagoub, Mohamed Hassan, Ishag Adam, Hamdan Z. Hamdan

مصطلحات موضوعية: Pathophysiology and Management of Preeclampsia, Obstetrics and Gynecology, Medicine, Health Sciences, Preeclampsia, Hepcidin, Iron status, Pregnancy, Interleukin 6, Internal medicine, Endocrinology, Immunology, FOS Clinical medicine, Physiology, FOS Biological sciences, Iron deficiency, Inflammation, Biology, Anemia, Genetics

العلاقة: https://dx.doi.org/10.60692/wq19b-af876Test

الإتاحة: https://doi.org/10.60692/z0wj1-3e74110.60692/wq19b-af876Test

المؤلفون: Marie Lorvellec, Anne Chouquet, Jonas Koch, Isabelle Bally, Luca Signor, Jeanne Vigne, Fabien Dalonneau, Nicole M. Thielens, Thierry Rabilloud, Bastien Dalzon, Véronique Rossi, Christine Gaboriaud

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, complement system, HMGB1 alarmin, cytokines, C1 protease, RAW264.7 cells, macrophage, inflammation, interleukin 6

العلاقة: https://figshare.com/articles/presentation/Presentation_1_HMGB1_cleavage_by_complement_C1s_and_its_potent_anti-inflammatory_product_pdf/22697914Test

الإتاحة: https://doi.org/10.3389/fimmu.2023.1151731.s001Test
https://figshare.com/articles/presentation/Presentation_1_HMGB1_cleavage_by_complement_C1s_and_its_potent_anti-inflammatory_product_pdf/22697914Test

المؤلفون: Xiao Ma, Bing Yang, Jie Ma

مصطلحات موضوعية: Impact of COVID-19 on Cancer Patients and Care, Oncology, Medicine, Health Sciences, Cancer Immunotherapy, Spontaneous Pneumomediastinum in COVID-19 Patients, Pulmonary and Respiratory Medicine, Tumor Microenvironment, Coronavirus disease 2019 COVID-19, Interleukin 10, Tumor necrosis factor alpha, Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2, Interleukin 6, Internal medicine, 2019-20 coronavirus outbreak, Mortality rate, Proinflammatory cytokine, Inflammation, Cancer research, Gastroenterology, Cytokine, Pathology, Disease, Outbreak, Infectious disease medical specialty

العلاقة: https://dx.doi.org/10.60692/408wh-aqp96Test

الإتاحة: https://doi.org/10.60692/d63aj-rda3910.60692/408wh-aqp96Test

المؤلفون: Spasov, A., Ovchinnikova, I., Fedorova, O., Titova, Y., Babkov, D., Kosolapov, V., Borisov, A., Sokolova, E., Klochkov, V., Skripka, M., Velikorodnaya, Y., Smirnov, A., Rusinov, G., Charushin, V.

المصدر: Molecules

مصطلحات موضوعية: CYTOKINE RELEASE, INFLAMMATION, LUNG INJURY, PYRIMIDINES, [1,2,4]TRIAZOLO[1,5-A]PYRIMIDINES, INTERLEUKIN 6, LIPOPOLYSACCHARIDE, PROTECTIVE AGENT, PYRIMIDINE DERIVATIVE, ACUTE LUNG INJURY, ANIMAL, CHEMISTRY, LUNG, MOUSE, ANIMALS, INTERLEUKIN-6, LIPOPOLYSACCHARIDES, MICE, PROTECTIVE AGENTS

وصف الملف: application/pdf

العلاقة: Spasov, A, Ovchinnikova, I, Fedorova, OV, Titova, Y, Babkov, D, Kosolapov, V, Borisov, A, Sokolova, E, Klochkov, V, Skripka, M, Velikorodnaya, Y, Smirnov, A, Rusinov, G & Charushin, V 2023, 'Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury', Molecules, Том. 28, № 2, 741. https://doi.org/10.3390/molecules28020741Test; Spasov, A., Ovchinnikova, I., Fedorova, O. V., Titova, Y., Babkov, D., Kosolapov, V., Borisov, A., Sokolova, E., Klochkov, V., Skripka, M., Velikorodnaya, Y., Smirnov, A., Rusinov, G., & Charushin, V. (2023). Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury. Molecules, 28(2), [741]. https://doi.org/10.3390/molecules28020741Test; Final; All Open Access, Gold, Green; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146661927&doi=10.3390%2fmolecules28020741&partnerID=40&md5=70b72ca2016b949c44f0ccc9a7e1a1deTest; https://www.mdpi.com/1420-3049/28/2/741/pdf?version=1674033724Test; http://elar.urfu.ru/handle/10995/130859Test; 85146661927; 000918798700001

الإتاحة: https://doi.org/10.3390/molecules28020741Test
http://elar.urfu.ru/handle/10995/130859Test
https://www.mdpi.com/1420-3049/28/2/741/pdf?version=1674033724Test

المؤلفون: Prystaz, Katja, Kaiser, Kathrin, Kovtun, Anna, Haffner-Luntzer, Melanie, Fischer, Verena, Rapp, Anna E., Liedert, Astrid, Strauss, Gudrun, Wätzig, Georg H., Rose-John, Stefan, Ignatius, Anita

مصطلحات موضوعية: Bone healing, Repair phase, DDC 610 / Medicine & health, Bone and bones, Fracture healing, Inflammation, Bone regeneration, Interleukin-6, Frakturheilung, Entzündung, Knochenregeneration, Interleukin 6

وصف الملف: application/pdf

العلاقة: https://ars.els-cdn.com/content/image/1-s2.0-S0002944017307137-figs1_lrg.jpgTest; https://ars.els-cdn.com/content/image/1-s2.0-S0002944017307137-figs2_lrg.jpgTest; https://www.sciencedirect.com/science/article/pii/S0002944017307137?via%3Dihub#ec1Test; https://ars.els-cdn.com/content/image/1-s2.0-S0002944017307137-figs3_lrg.jpgTest; http://dx.doi.org/10.18725/OPARU-49035Test; https://oparu.uni-ulm.de/xmlui/123456789/49111Test; http://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-49111-0Test

الإتاحة: https://doi.org/10.18725/OPARU-49035Test
https://oparu.uni-ulm.de/xmlui/123456789/49111Test
http://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-49111-0Test

المؤلفون: Lorvellec, Marie, Chouquet, Anne, Koch, Jonas, Bally, Isabelle, Signor, Luca, Vigne, Jeanne, Dalonneau, Fabien, Thielens, Nicole, Rabilloud, Thierry, Dalzon, Bastien, Rossi, Véronique, Gaboriaud, Christine

المساهمون: Protéomique pour la Microbiologie, l'Immunologie et la Toxicologie (PROMIT), Laboratoire de Chimie et Biologie des Métaux (LCBM - UMR 5249), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Grenoble Partnership for Structural Biology, Mass spectrometry facility of the Grenoble Instruct-ERIC Center ISBG, ANR-17-EURE-0003,CBH-EUR-GS,CBH-EUR-GS(2017), ANR-10-LABX-0049,GRAL,Grenoble Alliance for Integrated Structural Cell Biology(2010), ANR-21-CE14-0066,DYSALARM,Complément et alarmine dans les maladies inflammatoires chroniques(2021), ANR-16-CE91-0004,C1rsinEDS,Implications fonctionnelles des altérations des protéases C1r et C1s identifiées chez des patients atteints du syndrome Ehlers-Danlos de type parodontal.(2016), ANR-21-CO15-0001,COVI-COMPLECT,Role de la voie lectine du complément dans la pathogenèse de l'infection au SARS-CoV-2(2021)

المصدر: ISSN: 1664-3224.

مصطلحات موضوعية: complement system, HMGB1 alarmin, cytokines, C1 protease, RAW264.7 cells, macrophage, inflammation, interleukin 6, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM]

العلاقة: hal-04087444; https://hal.science/hal-04087444Test; https://hal.science/hal-04087444/documentTest; https://hal.science/hal-04087444/file/fimmu-14-1151731.pdfTest

الإتاحة: https://doi.org/10.3389/fimmu.2023.1151731Test
https://hal.science/hal-04087444Test
https://hal.science/hal-04087444/documentTest
https://hal.science/hal-04087444/file/fimmu-14-1151731.pdfTest

المؤلفون: N. N. Pakhtusov, A. O. Yusupova, A. S. Lishuta, O. A. Slepova, E. V. Privalova, Yu. N. Belenkov, Н. Н. Пахтусов, А. О. Юсупова, А. С. Лишута, О. A. Слепова, Е. В. Привалова, Ю. Н. Беленков

المساهمون: The study was financially supported by the Russian Science Foundation in the form of scientific project No. 22-15-00424, scientific grant "The role of activation of the WNT signaling cascade, the processes of its epigenetic regulation and immune-mediated inflammation in the progression of atherosclerosis and the possibility of influencing it by therapeutic neoangiogenesis in patients with stable ischemic heart disease"., Исследование выполнено при финансовой поддержке Российского научного фонда в виде научного проекта № 22-15-00424, научного гранта «Роль активации сигнального каскада WNT, процессов его эпигенетической регуляции и иммуноопосредованного воспаления в прогрессировании атеросклероза и возможности влияния на него методом терапевтического неоангиогенеза у пациентов со стабильной ишемической болезнью сердца».

المصدر: Rational Pharmacotherapy in Cardiology; Vol 19, No 1 (2023); 26-33 ; Рациональная Фармакотерапия в Кардиологии; Vol 19, No 1 (2023); 26-33 ; 2225-3653 ; 1819-6446

مصطلحات موضوعية: воспаление, interleukin 1β, interleukin 6, inflammation, интерлейкин 1β, интерлейкин 6

وصف الملف: application/pdf

العلاقة: https://www.rpcardio.com/jour/article/view/2892/2405Test; Tsao CW, Aday AW, Almarzooq ZI, et al. Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association. Circulation. 2022;145(8):e153-e639. DOI:10.1161/CIR.0000000000001052.; Payab M, Abedi M, Foroughi Heravani N et al. Brown adipose tissue transplantation as a novel alternative to obesity treatment: a systematic review. Int J Obes (London). 2021;45(1):109-21. DOI:10.1038/s41366-020-0616-5.; Liu C, Han D, Liang P, Li Y, Cao F. The Current Dilemma and Breakthrough of Stem Cell Therapy in Ischemic Heart Disease. Front Cell Dev Biol. 2021;9:636136. DOI:10.3389/fcell.2021.636136.; Müller P, Lemcke H, David R. Stem Cell Therapy in Heart Diseases - Cell Types, Mechanisms and Improvement Strategies. Cell Physiol Biochem. 2018;48(6):2607-55. DOI:10.1159/000492704.; Chacko L, P Howard J, Rajkumar C, et al. Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials. Circ Cardiovasc Qual Outcomes. 2020;13(2):e006363. DOI:10.1161/CIRCOUTCOMES.119.006363.; Soehnlein O, Libby P. Targeting inflammation in atherosclerosis - from experimental insights to the clinic. Nat Rev Drug Discov. 2021;20(8):589-610. DOI:10.1038/s41573-021-00198-1.; Cochain C, Zernecke A. Macrophages in vascular inflammation and atherosclerosis. Pflugers Arch. 2017;469(3-4):485-99. DOI:10.1007/s00424-017-1941-y.; Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996;87(6):2095-147. PMID:8630372.; IL6R Genetics Consortium Emerging Risk Factors Collaboration; Sarwar N, Butterworth AS, Freitag DFet al. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet. 2012;379(9822):1205-13. DOI:10.1016/S0140-6736(11)61931-4.; Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium; Swerdlow DI, Holmes MV, Kuchenbaecker KB, et al. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet. 2012;379(9822):1214-24. DOI:10.1016/S0140-6736(12)60110-X.; Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Low-dose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol. 2013;61(4):404-10. DOI:10.1016/j.jacc.2012.10.027.; Ridker PM, Everett BM, Thuren T, et al. CANTOS Trial Group. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J Med. 2017;377(12):1119-31. DOI:10.1056/NEJMoa1707914.; Radico F, Zimarino M, Fulgenzi F, et al. Determinants of long-term clinical outcomes in patients with angina but without obstructive coronary artery disease: a systematic review and meta-analysis. Eur Heart J. 2018;39(23):2135-46. DOI 10.1093/eurheartj/ehy185.; Jespersen L, Abildstrom SZ, Hvelplund A, et al. Burden of hospital admission and repeat angiography in angina pectoris patients with and without coronary artery disease: a registry-based cohort study. PLoS One. 2014;9(4):e93170. DOI:10.1371/journal.pone.0093170.; Shaw LJ, Merz CN, Pepine CJ, et al.; Women's Ischemia Syndrome Evaluation (WISE) Investigators. The economic burden of angina in women with suspected ischemic heart disease: results from the National Institutes of Health--National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome Evaluation. Circulation. 2006;114(9):894-904. DOI:10.1161/CIRCULATIONAHA.105.609990.; Faul F, Erdfelder E, Buchner A, Lang AG. Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods. 2009;41(4):1149-60. DOI:10.3758/BRM.41.4.1149.; Mohammad-Rezaei M, Ahmadi R, Rafiei A, et al. Serum levels of IL-32 in patients with coronary artery disease and its relationship with the serum levels of IL-6 and TNF-α. Mol Biol Rep. 2021;48(5):4263-71. DOI:10.1007/s11033-021-06441-7.; Ma W, Shen D, Liu J, et al. Statin Function as an Anti-inflammation Therapy for Depression in Patients With Coronary Artery Disease by Downregulating Interleukin-1β. J Cardiovasc Pharmacol. 2016;67(2):129-35. DOI:10.1097/FJC.0000000000000323.; Benjamin EJ, Muntner P, Alonso A, Virani SS, et al.; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation. 2019;139(10):e56-e528. DOI:10.1161/CIR.0000000000000659.; Koenig W. Inflammation Revisited: Atherosclerosis in The Post-CANTOS Era. Eur Cardiol. 2017;12(2):89-91. DOI:10.15420/ecr.2017:18:1.; Musher DM, Abers MS, Corrales-Medina VF. Acute Infection and Myocardial Infarction. N Engl J Med. 2019;380(2):171-6. DOI:10.1056/NEJMra1808137.; Sabatine MS, Giugliano RP, Keech AC, et al.; FOURIER Steering Committee and Investigators. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N Engl J Med. 2017;376(18):1713-22. DOI:10.1056/NEJMoa1615664.; Schuett H, Luchtefeld M, Grothusen C, et al. How much is too much? Interleukin-6 and its signalling in atherosclerosis. Thromb Haemost. 2009;102(2):215-22. DOI:10.1160/TH09-05-0297.; Schieffer B, Selle T, Hilfiker A, et al. Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis. Circulation. 2004;110(22):3493-500. DOI:10.1161/01.CIR.0000148135.08582.97.; Niu W, Liu Y, Qi Y, et al. Association of interleukin-6 circulating levels with coronary artery disease: a meta-analysis implementing mendelian randomization approach. Int J Cardiol. 2012;157(2):243-52. DOI:10.1016/j.ijcard.2011.12.098.; Held C, White HD, Stewart RAH, et al.; STABILITY Investigators. Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial. J Am Heart Assoc. 2017;6(10):e005077. DOI:10.1161/JAHA.116.005077.; Rai H, Colleran R, Cassese S, et al. Association of interleukin 6 -174 G/C polymorphism with coronary artery disease and circulating IL-6 levels: a systematic review and meta-analysis. Inflamm Res. 2021;70(10-12):1075-87. DOI:10.1007/s00011-021-01505-7.; Enayati S, Seifirad S, Amiri P, et al. Interleukin-1 beta, interferon-gamma, and tumor necrosis factor-alpha gene expression in peripheral blood mononuclear cells of patients with coronary artery disease. ARYA Atheroscler. 2015;11(5):267-74.; https://www.rpcardio.com/jour/article/view/2892Test

الإتاحة: https://doi.org/10.20996/1819-6446-2023-01-09Test
https://doi.org/10.1161/CIR.0000000000001052Test
https://doi.org/10.1038/s41366-020-0616-5Test
https://doi.org/10.3389/fcell.2021.636136Test
https://doi.org/10.1159/000492704Test
https://doi.org/10.1161/CIRCOUTCOMES.119.006363Test
https://doi.org/10.1038/s41573-021-00198-1Test
https://doi.org/10.1007/s00424-017-1941-yTest
https://doi.org/10.1016/S0140-6736Test(11)61931-4
https://doi.org/10.1016/S0140-6736Test(12)60110-X

المؤلفون: Livia Lenzini, Elisabetta Iori, Monica Vettore, Giorgia Gugelmo, Claudia Radu, Andrea Padoan, Gianni Carraro, Paolo Simioni, Lorenzo Calò, Angelo Avogaro, Gian Paolo Rossi, Nicola Vitturi

المصدر: Journal of Clinical Medicine, Vol 13, Iss 1, p 218 (2023)

مصطلحات موضوعية: Fabry disease, interleukin 6 receptor, exosomes, inflammation, Medicine

العلاقة: https://www.mdpi.com/2077-0383/13/1/218Test; https://doaj.org/toc/2077-0383Test; https://doaj.org/article/4e784599214e4d22bb1509edba329f96Test

الإتاحة: https://doi.org/10.3390/jcm13010218Test
https://doaj.org/article/4e784599214e4d22bb1509edba329f96Test

المؤلفون: Mengmeng Xiang, Yilun Wang, Qian Chen, Jie Wang, Zhanyan Gao, Jun Liang, Jinhua Xu

المصدر: Epigenetics, Vol 18, Iss 1 (2023)

مصطلحات موضوعية: systemic lupus erythematosus, inflammation, monocyte-derived dendritic cells, interleukin 6, cerna, long non-coding rna, Genetics, QH426-470

العلاقة: http://dx.doi.org/10.1080/15592294.2023.2226492Test; https://doaj.org/toc/1559-2294Test; https://doaj.org/toc/1559-2308Test; https://doaj.org/article/456a7206ef584a8ea887ce8bae6abf18Test

الإتاحة: https://doi.org/10.1080/15592294.2023.2226492Test
https://doaj.org/article/456a7206ef584a8ea887ce8bae6abf18Test

المؤلفون: Rui Lu, Ying-Guang Wang, Yunkun Qu, Shan-Xi Wang, Cheng Peng, Hongbo You, Wentao Zhu, Anmin Chen

المصدر: Bone & Joint Research, Vol 12, Iss 4, Pp 259-273 (2023)

مصطلحات موضوعية: dihydrocaffeic acid, osteoarthritis, chondrocyte, inflammation, mapk, nf-κb, cartilage degradation, chondrocytes, collagen ii, western blotting, aggrecan, mmp13, knee joints, interleukin 6, articular cartilage, Diseases of the musculoskeletal system, RC925-935

العلاقة: https://doaj.org/toc/2046-3758Test; https://doaj.org/article/8e2dec9b84224d96b5d0747e2c774266Test

الإتاحة: https://doi.org/10.1302/2046-3758.124.BJR-2022-0384.R1Test
https://doaj.org/article/8e2dec9b84224d96b5d0747e2c774266Test