المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/journal_contribution/Oligonucleotide_primers_used_in_this_study_/16542592Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s012Test

المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/journal_contribution/_i_P_i_i_aeruginosa_i_PA14_Tat_substrate_mutants_used_in_this_study_/16542595Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s013Test

المؤلفون: Joey Kuok Hoong Yam, Thet Tun Aung, Song Lin Chua, Yingying Cheng, Gurjeet Singh Kohli, Jianuan Zhou, Florentin Constancias, Yang Liu, Zhao Cai, May Margarette Santillan Salido, Daniela I. Drautz-Moses, Scott A. Rice, Stephan Christoph Schuster, Zhao Zhi Boo, Bin Wu, Staffan Kjelleberg, Tim Tolker-Nielsen, Rajamani Lakshminarayanan, Roger W. Beuerman, Liang Yang, Michael Givskov

المساهمون: School of Biological Sciences, Singapore Centre for Environmental Life Sciences and Engineering

المصدر: Infection and immunity, 90 (8)
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22Test

مصطلحات موضوعية: 06 Biological Sciences, 07 Agricultural and Veterinary Sciences, 11 Medical and Health Sciences, Immunology, mouse corneal infection, c-di-GMP, Gene Expression Regulation, Bacterial, Microbiology, immune response, type III secretion system, transcriptomics, Mice, Infectious Diseases, Bacterial Proteins, Pseudomonas aeruginosa, in vivo biofilms, Biofilms, Type III Secretion Systems, Animals, Parasitology, Medicine [Science], Transcriptomics, Cyclic GMP

وصف الملف: Print-Electronic; application/pdf; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabfddccbc986ff3c6cef4e563402a5Test
https://hdl.handle.net/10453/164130Test

المؤلفون: Hong Wu, Lulu Song, Joey Kuok Hoong Yam, Marian Plotkin, Hengzhuang Wang, Morten Rybtke, Dror Seliktar, Theodoros Kofidis, Niels Høiby, Tim Tolker-Nielsen, Zhijun Song, Michael Givskov

المصدر: Wu, H, Song, L, Yam, J K H, Plotkin, M, Wang, H, Rybtke, M, Seliktar, D, Kofidis, T, Høiby, N, Tolker-Nielsen, T, Song, Z & Givskov, M 2022, ' Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo ', Frontiers in Cellular and Infection Microbiology, vol. 12, 826450 . https://doi.org/10.3389/fcimb.2022.826450Test

مصطلحات موضوعية: Microbiology (medical), antibiotic resistance, Infectious Diseases, PF hydrogel, Pseudomonas aeruginosa, Immunology, in vivo model, biofilm infection, Microbiology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a69301f4f40f46f7c64c5904e2e45c1Test
https://doi.org/10.3389/fcimb.2022.826450Test

المؤلفون: Martin Nilsson, Kasper Nørskov Kragh, Michael Givskov, Tim Tolker-Nielsen, Morten Rybtke, Jens Bo Andersen, Louise Dahl Hultqvist, Tim Holm Jakobsen

المساهمون: Singapore Centre for Environmental Life Sciences and Engineering

المصدر: Antimicrob Agents Chemother

مصطلحات موضوعية: medicine.disease_cause, Microbiology, 03 medical and health sciences, Bacterial Proteins, Biofilm Dispersal, medicine, Phosphodiesterase, Pharmacology (medical), Cyclic GMP, Mechanisms of Action: Physiological Effects, Escherichia coli, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, Phosphoric Diester Hydrolases, 030306 microbiology, Pseudomonas aeruginosa, Chemistry, Escherichia coli Proteins, Biofilm, Gene Expression Regulation, Bacterial, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Environmental engineering [Engineering], Infectious Diseases, Biofilms, Second messenger system, Biological dispersal, Ectopic expression, Bacteria

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7665b26b0c1a3314ed127898bc779010Test
https://doi.org/10.1128/aac.02431-20Test

المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/figure/Exogenous_rhamnolipids_do_not_enhance_PQS-dependent_expression_of_i_pqsA_i_in_a_i_tatA_i_i_pqsA_i_mutant_PQS_40_M_was_added_with_or_without_purified_rhamnolipids_50_g_ml_to_a_i_pqsA_i_mutant_grey_bars_or_a_i_tatA_i_i_pqsA_i_mutant_pink_bars/16542553Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s005Test

المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/figure/The_Tat_inhibitor_Bayer_11_7082_has_no_effect_on_light_output_at_20_or_40_M_from_a_constitutive_i_P_i_i_aeruginosa_i_CTX_i_tac_-luxCDABE_i_chromosomal_reporter_fusion_/16542544Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s002Test

المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/figure/Biochemical_basis_of_AQ_biosynthesis_/16542541Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s001Test

المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/figure/Deletion_of_the_i_tatABC_i_genes_does_not_influence_i_pqsR_i_expression_/16542547Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s003Test

المؤلفون: Eliza Ye-Chen Soh (11356153), Frances Smith (11356156), Maxime Rémi Gimenez (11356159), Liang Yang (15035), Rebecca Munk Vejborg (11356162), Matthew Fletcher (437507), Nigel Halliday (797002), Sophie Bleves (474775), Stephan Heeb (91858), Miguel Cámara (141074), Michael Givskov (235463), Kim R. Hardie (8493378), Tim Tolker-Nielsen (243072), Bérengère Ize (848548), Paul Williams (191800)

مصطلحات موضوعية: Microbiology, Genetics, Infectious Diseases, Virology, Astronomical and Space Sciences not elsewhere classified, wild type levels, reduced bioluminescence revealed, reduced antibiotic tolerance, dependent quorum sensing, dependent autoinduction resulting, div >< p, defective biofilm architecture, >< sub ><, primary signalling defect, identify factors required, pseudomonas aeruginosa <, tat prevented pqs, >< sub xmlns, edna deficient biofilms, aeruginosa tat <, aeruginosa <, dependent qs, p <, biofilm maturation, tat <, tat substrate, sub xmlns, rieske sub, >, rhla <

العلاقة: https://figshare.com/articles/figure/HHQ_and_PQS_do_not_accumulate_intracellularly_in_a_i_tatA_i_i_pqsA_i_double_mutant_harboring_the_plasmid-borne_i_pqsABCD_i_genes_in_the_absence_of_autoinduction_/16542550Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009425.s004Test