التفاصيل البيبلوغرافية
| العنوان: |
Colon perforation after renal transplantation: a single-institution review |
| المؤلفون: |
Pirenne, Jacques, Lledo-Garcia, E, Benedetti, E, West, M, Hakim, N S, Sutherland, D E, Gruessner, R W, Najarian, J S, Matas, A J |
| سنة النشر: |
1997 |
| المجموعة: |
KU Leuven: Lirias |
| مصطلحات موضوعية: |
Adolescent, Adult, Aged, Child, Preschool, Colonic Diseases, Female, Graft Survival, Humans, Infant, Intestinal Perforation, Kidney Transplantation, Male, Middle Aged, Risk Factors |
| الوصف: |
Colon perforation (CP) is an uncommon but dramatic complication after renal transplantation. Of 1530 consecutive kidney transplants performed at our center, 8 recipients had an CP (incidence of 0.5%), either early (n = 5, 2-14 days) or late (n = 3, 8-48 months) post transplant. Clinical symptoms were generally vague. Biological findings were inconstant. Risk factors for CP included a cadaver graft (versus a living donor), high body weight, history of diverticulitis, and Kayexalate use. Crucial to outcome were: 1) immediate diagnosis and 2) aggressive surgical care consisting of resectional therapy, broad-spectrum antibiotics, and reduced immunosuppression. Applying these principles, mortality in our patients (25%) was lower than in previously reported series (33-64%). All grafts were functioning at the time of diagnosis; graft function was preserved in recipients who recovered from CP. Patients with a documented history of diverticulitis should undergo prophylactic colonic resection. Constipation and colonic dilatation should be treated aggressively in the early post-operative period. ; status: published |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
0902-0063 |
| العلاقة: |
Clinical transplantation vol:11 issue:2 pages:88-93; https://lirias.kuleuven.be/handle/123456789/14418Test |
| الإتاحة: |
https://lirias.kuleuven.be/handle/123456789/14418Test |
| رقم الانضمام: |
edsbas.A3D745EE |
| قاعدة البيانات: |
BASE |
