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1دورية أكاديمية
المؤلفون: Coleman, Robert L, Oza, Amit M, Lorusso, Domenica, Aghajanian, Carol, Oaknin, Ana, Dean, Andrew, Colombo, Nicoletta, Weberpals, Johanne I, Clamp, Andrew, Scambia, Giovanni, Leary, Alexandra, Holloway, Robert W, Gancedo, Margarita Amenedo, Fong, Peter C, Goh, Jeffrey C, O'Malley, David M, Armstrong, Deborah K, Garcia-Donas, Jesus, Swisher, Elizabeth M, Floquet, Anne, Konecny, Gottfried E, McNeish, Iain A, Scott, Clare L, Cameron, Terri, Maloney, Lara, Isaacson, Jeff, Goble, Sandra, Grace, Caroline, Harding, Thomas C, Raponi, Mitch, Sun, James, Lin, Kevin K, Giordano, Heidi, Ledermann, Jonathan A, investigators, ARIEL3, Buck, M, Dean, A, Friedlander, ML, Goh, JC, Harnett, P, Kichenadasse, G, Scott, CL, Denys, H, Dirix, L, Vergote, I, Elit, L, Ghatage, P, Oza, AM, Plante, M, Provencher, D, Weberpals, JI, Welch, S, Floquet, A, Gladieff, L, Joly, F, Leary, A, Lortholary, A, Lotz, J, Medioni, J, Tredan, O, You, B, El-Balat, A, Hänle, C, Krabisch, P, Neunhöffer, T, Pölcher, M, Wimberger, P, Amit, A, Kovel, S, Leviov, M, Safra, T, Shapira-Frommer, R, Stemmer, S, Bologna, A, Colombo, N, Lorusso, D, Pignata, S, Sabbatini, RF, Scambia, G, Tamberi, S, Zamagni, C, Fong, PC, O'Donnell, A, Gancedo, M Amenedo, Herraez, A Casado, Garcia-Donas, J, Guerra, EM, Oaknin, A, Palacio, I, Romero, I, Sanchez, A, Banerjee, SN, Clamp, A, Drew, Y, Gabra, HG, Jackson, D, Ledermann, JA, McNeish, IA, Parkinson, C, Powell, M
المصدر: The Lancet. 390(10106)
مصطلحات موضوعية: Reproductive Medicine, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Orphan Drug, Clinical Research, Cancer, Genetics, Clinical Trials and Supportive Activities, Ovarian Cancer, Rare Diseases, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, 6.2 Cellular and gene therapies, Aged, Disease-Free Survival, Double-Blind Method, Female, Follow-Up Studies, Humans, Indoles, Internationality, Maintenance Chemotherapy, Middle Aged, Molecular Targeted Therapy, Neoplasm Recurrence, Local, Ovarian Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors, Risk Assessment, Survival Rate, Treatment Outcome, ARIEL3 investigators, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/9xn4w6v7Test
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2دورية أكاديمية
المؤلفون: McNeish, IA, Kondrashova, O, Topp, M, Nesic, K, Lieschke, E, Ho, G-Y, Harrell, MI, Zapparoli, GV, Hadley, A, Holian, R, Boehm, E, Heong, V, Sanij, E, Pearson, RB, Krais, JJ, Johnson, N, McNally, O, Ananda, S, Alsop, K, Hutt, KJ, Kaufmann, SH, Lin, KK, Harding, TC, Traficante, N, DeFazio, A, Bowtell, DD, Swisher, EM, Dobrovic, A, Wakefield, MJ, Scott, CL
المساهمون: Imperial College Healthcare NHS Trust- BRC Funding, Cancer Research UK
مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, HOMOLOGOUS RECOMBINATION REPAIR, OLAPARIB MAINTENANCE THERAPY, SPORADIC BREAST-CANCER, POLYMERASE INHIBITORS, POLY(ADP-RIBOSE) POLYMERASE, PLATINUM RESPONSE, SOMATIC MUTATIONS, PROMOTER REGION, FALLOPIAN-TUBE, PHASE-2 TRIAL, Animals, Antineoplastic Agents, BRCA1 Protein, Cell Line, Tumor, Cisplatin, DNA Methylation, Female, Gene Dosage, Humans, Indoles, Kaplan-Meier Estimate, Mice, Inbred NOD, Knockout, SCID, Ovarian Neoplasms
العلاقة: Nature Communications; http://hdl.handle.net/10044/1/61797Test; https://dx.doi.org/10.1038/s41467-018-05564-zTest; RDB01; RG71079
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3دورية أكاديمية
المؤلفون: Swisher, EM, Lin, KK, Oza, AM, Scott, CL, Giordano, H, Sun, J, Konecny, GE, Coleman, RL, Tinker, AV, O'Malley, DM, Kristeleit, RS, Ma, L, Bell-McGuinn, KM, Brenton, JD, Cragun, JM, Oaknin, A, Ray-Coquard, I, Harrell, MI, Mann, E, Kaufmann, SH, Floquet, A, Leary, A, Harding, TC, Goble, S, Maloney, L, Isaacson, J, Allen, AR, Rolfe, L, Yelensky, R, Raponi, M, McNeish, IA
المصدر: Lancet Oncology , 18 (1) pp. 75-87. (2017)
مصطلحات موضوعية: Aged, Antineoplastic Agents, BRCA1 Protein, BRCA2 Protein, Drug Resistance, Neoplasm, Fallopian Tube Neoplasms, Female, Follow-Up Studies, Germ-Line Mutation, Humans, Indoles, International Agencies, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Peritoneal Neoplasms, Platinum, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, Prognosis, Prospective Studies, Salvage Therapy, Survival Rate
وصف الملف: text
العلاقة: https://discovery.ucl.ac.uk/id/eprint/10049690/1/Kristeleit_ARIEL2_HRD_Manuscript_Lancet_Oncol_09Sep2016%28clean%29.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10049690Test/
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4دورية أكاديمية
المؤلفون: Coleman, RL, Oza, AM, Lorusso, D, Aghajanian, C, Oaknin, A, Dean, A, Colombo, N, Weberpals, JI, Clamp, A, Scambia, G, Leary, A, Holloway, RW, Gancedo, MA, Fong, PC, Goh, JC, O'Malley, DM, Armstrong, DK, Garcia-Donas, J, Swisher, EM, Floquet, A, Konecny, GE, McNeish, IA, Scott, CL, Cameron, T, Maloney, L, Isaacson, J, Goble, S, Grace, C, Harding, TC, Raponi, M, Sun, J, Lin, KK, Giordano, H, Ledermann, JA, ARIEL3 investigators
المساهمون: Leidos Biomedical Research, Inc.
المصدر: 1961 ; 1949
مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Medicine, General & Internal, General & Internal Medicine, EPITHELIAL OVARIAN, SOLID TUMORS, OPEN-LABEL, CANCER, CHEMOTHERAPY, HETEROZYGOSITY, MULTICENTER, BEVACIZUMAB, Aged, Disease-Free Survival, Double-Blind Method, Female, Follow-Up Studies, Humans, Indoles, Internationality, Maintenance Chemotherapy, Middle Aged, Molecular Targeted Therapy, Neoplasm Recurrence, Local, Ovarian Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors, Risk Assessment, Survival Rate
العلاقة: Lancet; http://hdl.handle.net/10044/1/53951Test; TCGA Pilot Program; 15Y011ST
الإتاحة: https://doi.org/10.1016/S0140-6736Test(17)32440-6
http://hdl.handle.net/10044/1/53951Test -
5دورية أكاديمية
المؤلفون: Swisher, EM, Lin, KK, Oza, AM, Scott, CL, Giordano, H, Sun, J, Konecny, GE, Coleman, RL, Tinker, AV, O'Malley, DM, Kristeleit, RS, Ma, L, Bell-McGuinn, KM, Brenton, JD, Cragun, JM, Oaknin, A, Ray-Coquard, I, Harrell, MI, Mann, E, Kaufmann, SH, Floquet, A, Leary, A, Harding, TC, Goble, S, Maloney, L, Isaacson, J, Allen, AR, Rolfe, L, Yelensky, R, Raponi, M, McNeish, IA
المصدر: 87 ; 75
مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology, HOMOLOGOUS RECOMBINATION DEFICIENCY, POLY(ADP-RIBOSE) POLYMERASE, GENOMIC LOSS, DNA-REPAIR, MUTANT-CELLS, CANCER, BREAST, HETEROZYGOSITY, OLAPARIB, TUMORS, Aged, Antineoplastic Agents, BRCA1 Protein, BRCA2 Protein, Carcinoma, Ovarian Epithelial, Drug Resistance, Neoplasm, Fallopian Tube Neoplasms, Female, Follow-Up Studies, Germ-Line Mutation, Humans, Indoles, International Agencies, Middle Aged, Neoplasm Recurrence
العلاقة: Lancet Oncology; http://hdl.handle.net/10044/1/54675Test
الإتاحة: https://doi.org/10.1016/s1470-2045Test(16)30559-9
http://hdl.handle.net/10044/1/54675Test