المؤلفون: Ascierto, PA, McArthur, GA, Dréno, B, Atkinson, V, Liszkay, G, Di Giacomo, AM, Mandalà, M, Demidov, L, Stroyakovskiy, D, Thomas, L, de la Cruz-Merino, L, Dutriaux, C, Garbe, C, Yan, Y, Wongchenko, M, Chang, I, Hsu, JJ, Koralek, DO, Rooney, I, Ribas, A, Larkin, J

المساهمون: Larkin, James

مصطلحات موضوعية: Humans, Melanoma, Skin Neoplasms, Neoplasm Metastasis, Sulfonamides, Azetidines, Piperidines, Indoles, Proto-Oncogene Proteins B-raf, Antineoplastic Combined Chemotherapy Protocols, Neoplasm Staging, Prognosis, Survival Rate, Follow-Up Studies, Double-Blind Method, Mutation, Adult, Aged, 80 and over, Middle Aged, Female, Male, Young Adult, Biomarkers, Tumor, Vemurafenib

وصف الملف: Print-Electronic; 1260; application/pdf

العلاقة: The Lancet. Oncology, 2016, 17 (9), pp. 1248 - 1260; https://repository.icr.ac.uk/handle/internal/664Test

الإتاحة: https://doi.org/10.1016/s1470-2045Test(16)30122-x
https://repository.icr.ac.uk/handle/internal/664Test

المؤلفون: Larkin, James, Ascierto, Paolo A, Dréno, Brigitte, Atkinson, Victoria, Liszkay, Gabriella, Maio, Michele, Mandalà, Mario, Demidov, Lev, Stroyakovskiy, Daniil, Thomas, Luc, de la Cruz-Merino, Luis, Dutriaux, Caroline, Garbe, Claus, Sovak, Mika A, Chang, Ilsung, Choong, Nicholas, Hack, Stephen P, McArthur, Grant A, Ribas, Antoni

المساهمون: Larkin,J Royal Marsden Hospital, London. Ascierto,PA Istituto Nazionale Tumori Fondazione G. Pascale, Naples,Italy. Dréno,B Hôtel Dieu Place Alexis Ricordeau,Nantes,France. Atkinson,V Princess Alexandra Hospital, Woolloongabba, QLD,Australia. Liszkay,G National Institute of Oncology, Budapest, Hungary. Maio,M Azienda Ospedaliera Universitaria Senese, Siena,Italy. Mandalà,M Papa Giovanni XXIII Hospital, Bergamo,Italy. Demidov,L Blokhin Russian Cancer Research Center, Moscow,Russia. Stroyakovskiy,D Moscow City Oncology Hospital 62, Krasnogorsk, Russia. Thomas,L Centre Hospitalier Lyon Sud, Pierre-Bénite,France. de la Cruz-Merino,L Hospital Universitario Virgen Macarena, Seville, Spain. Dutriaux,C Hôpital Saint André, Bordeaux,France. Garbe,C University of Tübingen, Tübingen, Germany. Sovak,MA, Chang,I, Choong,N, Hack,SP Genentech, South San Francisco. Ribas,A Jonsson Comprehensive Cancer Center at the University of California, Los Angeles., Supported by F. Hoffmann–La Roche/Genentech.

مصطلحات موضوعية: Indoles, Sulfonamides, Proto-oncogene proteins B-raf, MAP quinasa quinasa 1, Azetidines, Piperidinas, Sulfonamidas, Azetidinas, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols::Antineoplastic Protocols::Antineoplastic Combined Chemotherapy Protocols, Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azetines::Azetidines, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, 2-Ring::Indoles, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Survival Analysis::Kaplan-Meier Estimate, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Mitogen-Activated Protein Kinase Kinases::MAP Kinase Kinase 1, Medical Subject Headings::Check Tags::Male, Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Nevi and Melanomas::Melanoma, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged, Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation, 1-Ring::Piperidines, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Oncogene Proteins::Proto-Oncogene Proteins::raf Kinases::Proto-Oncogene Proteins B-raf, Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Sulfones::Sulfonamides, Medical Subject Headings::Information Science::Information Science::Data Collection::Vital Statistics::Mortality::Survival Rate, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult

وصف الملف: application/pdf

العلاقة: Larkin J, Ascierto PA, Dréno B, Atkinson V, Liszkay G, Maio M, et al. Combined vemurafenib and cobimetinib in BRAF-mutated melanoma. N. Engl. J. Med. 2014; 371(20):1867-76; http://hdl.handle.net/10668/2159Test

الإتاحة: https://doi.org/10.1056/NEJMoa1408868Test
http://hdl.handle.net/10668/2159Test

المؤلفون: Stephen P. Hack, James Larkin, Luis de la Cruz-Merino, Grant A. McArthur, Luc Thomas, Nicholas Choong, Claus Garbe, Gabriella Liszkay, Victoria Atkinson, Daniil Stroyakovskiy, Ilsung Chang, Lev V. Demidov, Mario Mandalà, Caroline Dutriaux, Brigitte Dréno, Antoni Ribas, Mika A. Sovak, Paolo A. Ascierto, Michele Maio

المساهمون: [Larkin,J] Royal Marsden Hospital, London.[Ascierto,PA] Istituto Nazionale Tumori Fondazione G. Pascale, Naples,Italy. [Dréno,B] Hôtel Dieu Place Alexis Ricordeau,Nantes,France. [Atkinson,V] Princess Alexandra Hospital, Woolloongabba, QLD,Australia. [Liszkay,G] National Institute of Oncology, Budapest, Hungary. [Maio,M] Azienda Ospedaliera Universitaria Senese, Siena,Italy. [Mandalà,M] Papa Giovanni XXIII Hospital, Bergamo,Italy. [Demidov,L] Blokhin Russian Cancer Research Center, Moscow,Russia. [Stroyakovskiy,D] Moscow City Oncology Hospital 62, Krasnogorsk, Russia. [Thomas,L] Centre Hospitalier Lyon Sud, Pierre-Bénite,France. [de la Cruz-Merino,L] Hospital Universitario Virgen Macarena, Seville, Spain. [Dutriaux,C] Hôpital Saint André, Bordeaux,France. [Garbe,C] University of Tübingen, Tübingen, Germany. [Sovak,MA, Chang,I, Choong,N, Hack,SP] Genentech, South San Francisco.[Ribas,A] Jonsson Comprehensive Cancer Center at the University of California, Los Angeles., Supported by F. Hoffmann–La Roche/Genentech.

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Indoles, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings], Information Science::Information Science::Data Collection::Vital Statistics::Mortality::Survival Rate [Medical Subject Headings], Azetidinas, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Mitogen-Activated Protein Kinase Kinases::MAP Kinase Kinase 1 [Medical Subject Headings], Check Tags::Male [Medical Subject Headings], Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], chemistry.chemical_compound, Internal medicine, medicine, Piperidinas, Named Groups::Persons::Age Groups::Adult [Medical Subject Headings], Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings], Vemurafenib, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Indoles [Medical Subject Headings], Survival rate, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival [Medical Subject Headings], Diseases::Neoplasms::Neoplasms by Histologic Type::Nevi and Melanomas::Melanoma [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols::Antineoplastic Protocols::Antineoplastic Combined Chemotherapy Protocols [Medical Subject Headings], Cobimetinib, Trametinib, Sulfonamides, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Survival Analysis::Kaplan-Meier Estimate [Medical Subject Headings], business.industry, MEK inhibitor, Melanoma, Sulfonamidas, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azetines::Azetidines [Medical Subject Headings], Binimetinib, Dabrafenib, General Medicine, medicine.disease, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Piperidines [Medical Subject Headings], Surgery, Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Sulfones::Sulfonamides [Medical Subject Headings], MAP quinasa quinasa 1, chemistry, Check Tags::Female [Medical Subject Headings], Proto-oncogene proteins B-raf, Azetidines, business, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Oncogene Proteins::Proto-Oncogene Proteins::raf Kinases::Proto-Oncogene Proteins B-raf [Medical Subject Headings], medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058bae456f14e0981fcd75b5620ef91eTest
https://hdl.handle.net/10668/2159Test