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1صورة
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s006Test
https://figshare.com/articles/figure/Bidirectional_MR_analysis_revealed_no_reversal_causal_effects_of_DR_on_ALT_and_AST_/25015105Test -
2صورة
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s002Test
https://figshare.com/articles/figure/Scatter_plots_displayed_the_casual_effects_of_serum_ALT_and_AST_levels_on_the_risk_of_DR_overall_and_T2DM_with_DR_/25015093Test -
3صورة
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s003Test
https://figshare.com/articles/figure/The_symmetry_of_funnel_plots_indicated_a_balanced_pleiotropy_/25015096Test -
4صورة
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s005Test
https://figshare.com/articles/figure/Leave-one-out_results_demonstrated_no_individual_SNPs_that_could_significantly_affect_the_causal_effects_of_AST_on_DR_/25015102Test -
5
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s007Test
https://figshare.com/articles/dataset/Detailed_information_for_the_datasets_of_the_exposures_and_outcomes_/25015108Test -
6
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
العلاقة: https://figshare.com/articles/dataset/The_SNPs_that_were_palindromic_or_incompatible_/25015132Test
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s013Test
https://figshare.com/articles/dataset/The_SNPs_that_were_palindromic_or_incompatible_/25015132Test -
7
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s012Test
https://figshare.com/articles/dataset/The_SNPs_that_were_lost_in_the_GWAS_summary_data_of_the_outcome_/25015129Test -
8
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s009Test
https://figshare.com/articles/dataset/Detailed_information_of_genetic_instruments_for_AST_/25015120Test -
9
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s011Test
https://figshare.com/articles/dataset/Detailed_information_of_genetic_instruments_for_GGT_/25015126Test -
10
مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Science Policy, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, wide association study, sup > 8722, single nucleotide polymorphisms, potential biological mechanisms, pleiotropy residual sum, multivariable mendelian randomization, 5 × 10, serum aspartate aminotransferase, serum alanine aminotransferase, wide significance (<, independent causal effect, diabetic microvascular complications, alp ), gamma, 206 – 1, 115 – 1, univariable mendelian randomization, three mvmr approaches, previous observational investigations, five uvmr approaches, diabetes risk factors, independent causal effects
الإتاحة: https://doi.org/10.1371/journal.pone.0296894.s017Test
https://figshare.com/articles/dataset/The_SNPs_that_were_utilized_in_MVMR_/25015144Test