نتائج البحث - "indoleamine-2"

1

Tryptophan Catabolism as Immune Mechanism of Primary Resistance to Anti-PD-1

المؤلفون: Silvia Mezi, Simone Scagnoli, Alessio Cortellini, Andrea Botticelli, Bruna Cerbelli, Marianna Nuti, Ilaria Grazia Zizzari, Luana Lionetto, Maurizio Simmaco, Raffaele Giusti, Edoardo Cerbelli, Paolo Marchetti, Michela Roberto, Giulia Pomati

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Programmed Cell Death 1 Receptor, indoleamine-2, Gastroenterology, Metastasis, 0302 clinical medicine, Renal cell carcinoma, Neoplasms, Odds Ratio, Medicine, Immunology and Allergy, Prospective cohort study, Immune Checkpoint Inhibitors, Original Research, Aged, 80 and over, education.field_of_study, Hazard ratio, Tryptophan, indoleamine-2,3-dioxygenase, anti-pd-1, kynurenine, tryptophan metabolism, tumor immunity, Middle Aged, Prognosis, Primary tumor, Treatment Outcome, 3-dioxygenase, Female, Nivolumab, lcsh:Immunologic diseases. Allergy, medicine.medical_specialty, Population, Immunology, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, Biomarkers, Tumor, Humans, education, Aged, Neoplasm Staging, business.industry, medicine.disease, Head and neck squamous-cell carcinoma, 030104 developmental biology, Drug Resistance, Neoplasm, Neoplasm Grading, business, lcsh:RC581-607, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11e33e0a00cd114f54002e90f341879Test
http://hdl.handle.net/11573/1434713Test

2

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation

المؤلفون: Christiane A. Opitz, Adam J. Rose, Ines Heiland, Saskia Trump, Michael Platten, Joram Mooiweer, Melanie Keil, Dyah L. Dewi, Soumya R. Mohapatra, Bianca Berdel, Jana K. Sonner, Isabell Adam, Kathrin Thedieck, Ahmed Sadik

المصدر: OncoImmunology, 7(12):1486353. Taylor & Francis Group
OncoImmunology, Vol 7, Iss 12 (2018)
Oncoimmunology

مصطلحات موضوعية: 0301 basic medicine, lcsh:Immunologic diseases. Allergy, ARYL-HYDROCARBON RECEPTOR, tumor, tRNA synthetase, AMINO-ACID TRANSPORTER, inflammation and cancer, proliferation, Immunology, cancer metabolism, immunosurveillance, Activating Transcription Factor 4, Indoleamine-2, TRANSLATIONAL CONTROL, lcsh:RC254-282, 03 medical and health sciences, tryptophan-2, 0302 clinical medicine, Downregulation and upregulation, nutrients, MAMMALIAN-CELLS, Protein biosynthesis, Immunology and Allergy, Initiation factor, tryptophan, Indoleamine 2,3-dioxygenase, INDOLEAMINE 2, Original Research, GENE-EXPRESSION, RESPONSE PATHWAY, immunosuppression, Kinase, Chemistry, ATF4, starvation, TUMORAL IMMUNE RESISTANCE, EPITHELIAL-CELLS, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell biology, 030104 developmental biology, 3-dioxygenase, Oncology, 030220 oncology & carcinogenesis, T-CELLS, Phosphorylation, Indoleamine-2, 3-dioxygenase, lcsh:RC581-607, INDOLEAMINE 2,3-DIOXYGENASE

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d850db9c0fda85f070d5c186bb8378Test
https://research.rug.nl/en/publications/5a66a80a-9fd2-4ca7-a2f4-5150526fd88bTest

3

Disease tolerance mediated by phosphorylated indoleamine-2,3 dioxygenase confers resistance to a primary fungal pathogen

المؤلفون: Paolo Puccetti, Claudia Feriotti, Luigina Romani, Carmine Vacca, Eliseu Frank de Araújo, Tania Alves da Costa, Flávio V. Loures, Vera Lúcia Garcia Calich

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, Disease tolerance, T cell, Immunology, Inflammation, Biology, 3 dioxygenase, Indoleamine-2, ENZIMAS OXIRREDUTORAS, Microbiology, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Pulmonary dendritic cells, Immunity, medicine, Immunology and Allergy, Indoleamine 2,3-dioxygenase, Pathogen, Indoleamine-2,3 dioxygenase, Paracoccidioidomycosis, Phosphorylated indoleamine-2,3 dioxygenase, Signaling function, indoleamine-2,3 dioxygenase, phosphorylated indoleamine-2,3 dioxygenase, Original Research, Phosphorylated indoleamine-2, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Phosphorylation, medicine.symptom, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0b26f462e70a7a7443857304ebcb70Test
http://hdl.handle.net/11391/1425780Test

4

The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells

المؤلفون: Young-Seung Kim, Martin W. Brechbiel, Kwong Y. Tsang, Anna R. Kwilas, Massimo Fantini, Ravi A. Madan, James L. Gulley, Caroline Jochems, Christopher R. Heery, Robert C. Newton, Italia Grenga, Lauren M. Lepone, Jeffrey Schlom, Romaine I. Fernando, James W. Hodge, Renee N. Donahue

المصدر: Oncotarget

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, 3-dioxygenase (IDO), indoleamine-2, Lymphocyte Activation, 0302 clinical medicine, Oximes, Cytotoxic T cell, Medicine, Kynurenine, Sulfonamides, Tryptophan, hemic and immune systems, Middle Aged, Healthy Volunteers, Tumor antigen, Phenotype, Oncology, 030220 oncology & carcinogenesis, Female, Tumor necrosis factor alpha, Research Paper, Adult, T cells, chemical and pharmacologic phenomena, Tregs, Cancer Vaccines, Peripheral blood mononuclear cell, Interferon-gamma, Young Adult, 03 medical and health sciences, Immune system, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, dendritic cells, Aged, business.industry, Granulocyte-Macrophage Colony-Stimulating Factor, Cancer, Dendritic cell, medicine.disease, CTL, 030104 developmental biology, Immunology, Leukocytes, Mononuclear, Peptides, business, T-Lymphocytes, Cytotoxic, IDO inhibitor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1070afce2000de3f9372fe1029410bbeTest
https://doi.org/10.18632/oncotarget.9326Test

5

Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy

المؤلفون: Hiroaki Nonaka, Hiroaki Mizukami, Keiya Ozawa, Naoto Sato, Hiroyuki Fujiwara, Dongdong Wang, Yuji Takei, Yasushi Saga, Mitsuaki Suzuki, Shizuo Machida, Osamu Takikawa

المصدر: International Journal of Oncology

مصطلحات موضوعية: Cancer Research, endocrine system diseases, Cell, Down-Regulation, Mice, Nude, Biology, indoleamine-2, Transfection, Mice, Downregulation and upregulation, Cell Line, Tumor, medicine, short hairpin RNA, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, RNA, Small Interfering, Indoleamine 2,3-dioxygenase, Ovarian Neoplasms, Mice, Inbred BALB C, Oncogene, Cancer, peritoneal dissemination, Articles, Cell cycle, natural killer cell, medicine.disease, Immunohistochemistry, Xenograft Model Antitumor Assays, female genital diseases and pregnancy complications, Killer Cells, Natural, medicine.anatomical_structure, ovarian cancer, 3-dioxygenase, Oncology, Immunology, Cancer cell, Cancer research, Disease Progression, Female, Ovarian cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e917bf5c7debf7118d07a281b003d8Test
http://europepmc.org/articles/PMC3584823Test

6

Association of a polymorphism in the indoleamine- 2,3-dioxygenase gene and interferon-α-induced depression in patients with chronic hepatitis C

المؤلفون: Jason S. Simon, Alicia K. Smith, Andrew H. Miller, Clifford A. Brass, Michael P. Epstein, Ping Qiu, David James Devlin, Eric L. Gustafson, Mark S. Sulkowski, Stephanie Noviello, Joseph F. Cubells, John G. McHutchinson, Janice K. Albrecht

المصدر: Molecular psychiatry

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Genotype, Alpha interferon, Locus (genetics), Single-nucleotide polymorphism, Interferon alpha-2, indoleamine-2, Biology, Antiviral Agents, Gastroenterology, White People, Article, Polyethylene Glycols, Cellular and Molecular Neuroscience, interferon-α, single nucleotide polymorphism, Interferon, Internal medicine, medicine, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Genetic Predisposition to Disease, Allele, Promoter Regions, Genetic, genes, Molecular Biology, Alleles, Randomized Controlled Trials as Topic, Psychiatric Status Rating Scales, Polymorphism, Genetic, Depression, Interferon-alpha, Odds ratio, Hepatitis C, Chronic, Middle Aged, Center for Epidemiologic Studies Depression Scale, Recombinant Proteins, cytokines, Black or African American, Psychiatry and Mental health, 3-dioxygenase, Immunology, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8358e4933f24153be464cfc608374aTest
https://doi.org/10.1038/mp.2011.67Test

7

Tryptophan feeding of the IDO1-AhR axis in host-microbial symbioses

المؤلفون: Silvia Moretti, Rossana G. Iannitti, Antonella De Luca, Marco Gargaro, Luigina Romani, Teresa Zelante, Andrea Bartoli, Francesca Fallarino

المصدر: Frontiers in Immunology, Vol 5 (2014)
Frontiers in Immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b82899c08b2348717d1e1d121568859Test
http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00640/fullTest

8

Downregulation of indoleamine-2,3-dioxygenase in cervical cancer cells suppresses tumor growth by promoting natural killer cell accumulation

المؤلفون: Suzuyo Takahashi, Yuji Takei, Hiroaki Mizukami, Hiroyuki Fujiwara, Osamu Takikawa, Naoto Sato, Yasushi Saga, Keiya Ozawa, Shizuo Machida, Dongdong Wang, Mitsuaki Suzuki, Hiroaki Nonaka

المصدر: Oncology Reports

مصطلحات موضوعية: Cancer Research, cervical cancer, Cell, Transplantation, Heterologous, Down-Regulation, Uterine Cervical Neoplasms, Biology, indoleamine-2, Lymphocyte Activation, Natural killer cell, Interferon-gamma, Mice, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, short hairpin RNA, RNA, Small Interfering, Cell Proliferation, Mice, Inbred BALB C, Oncogene, Cell growth, Cancer, General Medicine, Articles, Cell cycle, natural killer cell, medicine.disease, Killer Cells, Natural, medicine.anatomical_structure, 3-dioxygenase, Oncology, Immunology, Cancer cell, Cancer research, Disease Progression, Female, RNA Interference, Neoplasm Transplantation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219a2c3d399b2930f3b9cad5b2e3cad8Test
https://pubmed.ncbi.nlm.nih.gov/22923135Test

9

CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2, 3-dioxygenase

المؤلفون: Megan Sykes, Thomas Wekerle, Felix B. Langer, Ines Pree, Christiana Winkler, Patrick Nierlich, Sinda Bigenzahn, Dietmar Fuchs, Ferdinand Muehlbacher, Zvonimir Koporc, Gerald Brandacher

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb40e5282bfa33c457d535bf03b72937Test
https://www.bib.irb.hr/492998Test

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