Effects of Dexamethasone on Contralateral Testicular Immune Response in Wistar Strain Rats with Unilateral Testicular Torsion
| العنوان: | Effects of Dexamethasone on Contralateral Testicular Immune Response in Wistar Strain Rats with Unilateral Testicular Torsion |
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| المؤلفون: | Andri Kustono, Tarmono Tarmono, Fikri Rizaldi, I Ketut Sudiana |
| المصدر: | Folia Medica Indonesiana; Vol. 54 No. 1 (2018): March; 29-33 Folia Medica Indonesiana, Vol 54, Iss 1, Pp 29-33 (2018) |
| بيانات النشر: | Universitas Airlangga, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, Spermatogonium, Eosin, IgG, business.industry, lcsh:R, Urology, lcsh:Medicine, spermatogonium, medicine.disease, Dexamethasone, testicular torsion, Staining, chemistry.chemical_compound, Seminiferous tubule, medicine.anatomical_structure, Immune system, chemistry, medicine, Testicular torsion, Immunohistochemistry, business, medicine.drug |
| الوصف: | The aim of this study was to prove the effects of dexamethasone on immune responses in rats with testicular torsion. This was an experimental study with post test only control group design. In this study, 27 rats were randomly divided into 3 groups. In normal or sham group (CN) orchidectomy was performed on the right testis on day 14. The positive control group (CP) had testicular torsion for 10 h, then manual detorsion was performed after 4 h, and on day 14 orchidectomy was performed on ipsilateral and contralateral testes. The treatment group (N) had testicular torsion for 10 h and received 10 mg/kgBW dexamethasone subcutaneously 30 minutes before manual detorsion 4 hours later, and on day 14 orchidectomy was performed to ipsilateral and contralateral testes. The spermatogonium count was calculated based on the average number of intratubular seminiferous tubule section observed in contralateral testicular incision with Haematoxiliyn Eosin (HE) staining. IgG count was calculated based on the average number of extratubular seminiferous tubules observed at 5 contralateral testicular incision with immunohistochemical staining (IHC). The number of spermatogonia was significantly different between CN and CP, CN and N, and CP and N (p |
| وصف الملف: | application/pdf |
| تدمد: | 2599-056X 2355-8393 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3f409032d3584ef0802b9180c3975eTest https://doi.org/10.20473/fmi.v54i1.8049Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....db3f409032d3584ef0802b9180c3975e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2599056X 23558393 |
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