التفاصيل البيبلوغرافية
| العنوان: |
The IRG1/itaconate/TFEB axis: A new weapon in macrophage antibacterial defense. |
| المؤلفون: |
Martina, José A.1 (AUTHOR), Puertollano, Rosa1 (AUTHOR) puertolr@mail.nih.gov |
| المصدر: |
Molecular Cell. Aug2022, Vol. 82 Issue 15, p2732-2734. 3p. |
| مصطلحات موضوعية: |
*IMMUNE response, *WEAPONS, *MITOCHONDRIA |
| مستخلص: |
Zhang et al. (2022) report that itaconate, a mitochondrial metabolite produced by macrophages upon inflammatory stimuli, activates the master regulator of lysosomal biogenesis TFEB to facilitate clearance of invading bacteria and efficient immune response. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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