التفاصيل البيبلوغرافية
| العنوان: |
WHO and ATPIII proposals for the definition of the metabolic syndrome in patients with Type 2 diabetes. |
| المؤلفون: |
Marchesini, G., Forlani, G., Cerrelli, F., Manini, R., Natale, S., Baraldi, L., Ermini, G., Savorani, G., Zocchi, D., Melchionda, N. |
| المصدر: |
Diabetic Medicine; Apr2004, Vol. 21 Issue 4, p383-387, 5p |
| مصطلحات موضوعية: |
TYPE 2 diabetes, DIAGNOSIS of diabetes, SYNDROMES, ASSOCIATIONS, institutions, etc., CARDIOVASCULAR diseases, HIGH density lipoproteins, CHOLESTEROL |
| مستخلص: |
Different criteria have been proposed by the World Health Organization (WHO) and by the Third Report of the National Cholesterol Education Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATPIII) for the diagnosis of the metabolic syndrome. Its identification is of particular importance for coronary risk assessment. The prevalence of the metabolic syndrome was determined according to the two different proposals in 1569 consecutive subjects with Type 2 diabetes. By the WHO proposal, 81% of cases (95% confidence interval, 79–83) were labelled as metabolic syndrome. Microalbuminuria had the highest specificity (99%) and visceral obesity the highest sensitivity (93%). Seventy-eight per cent of patients (95% CI, 76–80) fulfilled the ATPIII criteria for metabolic syndrome, low HDL-cholesterol having the highest specificity (95%), elevated blood pressure having the highest sensitivity. According to both proposals, 1113 patients were positive; 183 were concordantly negative, indicative of a fairly good agreement ( k statistics, 0.464). Subjects only positive for the WHO proposal were more frequently males, had a lower BMI and a higher arterial pressure. Only subjects identified by the ATPIII proposal had a significantly higher prevalence of previously detected coronary heart disease. Minimum criteria for the metabolic syndrome are met in most patients with Type 2 diabetes. Correct identification of the syndrome is important for an integrated approach to reduce the high costs and the associated disabilities. The ATPIII proposal more clearly identifies the burden of coronary heart disease associated with the metabolic syndrome. Diabet. Med. (2004) [ABSTRACT FROM AUTHOR] |
|
Copyright of Diabetic Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
