المؤلفون: Hu, Lanlin, Li, Hua, Lee, Eliot D, Grandis, Jennifer R, Bauman, Julie E, Johnson, Daniel E

المصدر: Molecular Medicine Reports. 20(6)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Rare Diseases, Cancer, Complementary and Integrative Health, Dental/Oral and Craniofacial Disease, Nutrition, Biotechnology, Genetics, Prevention, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Anticarcinogenic Agents, Antigens, Differentiation, T-Lymphocyte, Cell Line, Tumor, Gene Expression Profiling, Gene Expression Regulation, Humans, Isothiocyanates, NK Cell Lectin-Like Receptor Subfamily K, Oxidative Stress, Squamous Cell Carcinoma of Head and Neck, Sulfoxides, Transcriptome, sulforaphane, head and neck squamous cell carcinoma, chemoprevention, heme oxygenase 1, heat shock protein family A (Hsp70) member 1A, Biochemistry and Cell Biology, Oncology & Carcinogenesis, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4nd429p1Test

المؤلفون: Kampinga, Harm H, Andreasson, Claes, Barducci, Alessandro, Cheetham, Michael E, Cyr, Douglas, Emanuelsson, Cecilia, Genevaux, Pierre, Gestwicki, Jason E, Goloubinoff, Pierre, Huerta-Cepas, Jaime, Kirstein, Janine, Liberek, Krzysztof, Mayer, Matthias P, Nagata, Kazuhiro, Nillegoda, Nadinath B, Pulido, Pablo, Ramos, Carlos, De los Rios, Paolo, Rospert, Sabine, Rosenzweig, Rina, Sahi, Chandan, Taipale, Mikko, Tomiczek, Bratłomiej, Ushioda, Ryo, Young, Jason C, Zimmermann, Richard, Zylicz, Alicja, Zylicz, Maciej, Craig, Elizabeth A, Marszalek, Jaroslaw

المصدر: Cell Stress and Chaperones. 24(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Animals, Disease, Evolution, Molecular, HSP70 Heat-Shock Proteins, Humans, Protein Aggregates, Protein Domains, Protein Refolding, Heat shock protein 70, J-domain proteins, 8-stranded -sandwich domain, 8-stranded β-sandwich domain, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9940787wTest

المؤلفون: Elnatan, Daniel, Agard, David A

المصدر: Journal of Biological Chemistry. 293(35)

مصطلحات موضوعية: Biochemistry and Cell Biology, Medical Physiology, Biomedical and Clinical Sciences, Biological Sciences, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Adenosine Triphosphatases, Animals, Calcium, Crystallography, X-Ray, Humans, Magnesium, Mitochondria, Models, Molecular, Protein Binding, TNF Receptor-Associated Factor 1, Zebrafish, Zebrafish Proteins, chaperone, heat shock protein 90, mitochondria, calcium-binding protein, ATPase, ATP hydrolysis, magnesium cofactor, TNF receptor-associated protein 1, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3tg431n0Test

المؤلفون: Alves, Raquel, Santos, Diogo, Jorge, Joana, Gonçalves, Ana Cristina, Catarino, Steve, Girão, Henrique, Melo, Joana Barbosa, Sarmento-Ribeiro, Ana Bela

مصطلحات موضوعية: heat shock protein, imatinib resistance, chronic myeloid leukemia, Humans, Apoptosis, Cell Line, Tumor, Drug Resistance, Neoplasm, Fusion Proteins, bcr-abl, Heat-Shock Proteins, Imatinib Mesylate, K562 Cells, HSP90 Heat-Shock Proteins, Antineoplastic Agents, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; UID/NEU/04539/2013; UID/NEU/04539/2019; POCI-01-0145-FEDER-007440; SFRH/BD/51994/2012; SFRH/BD/145531/2019; https://hdl.handle.net/10316/114065Test

الإتاحة: https://doi.org/10.3390/molecules28031210Test
https://hdl.handle.net/10316/114065Test

المؤلفون: Samant, RS, Batista, S, Larance, M, Ozer, B, Milton, CI, Bludau, I, Wu, E, Biggins, L, Andrews, S, Hervieu, A, Johnston, HE, Al-Lazikhani, B, Lamond, AI, Clarke, PA, Workman, P

المساهمون: Hervieu Vilches, Alexia, Clarke, Paul, Workman, Paul

مصطلحات موضوعية: HSP90 inhibitor, heat shock protein, molecular chaperone, protein complexes, proteomics, tanespimycin, Humans, Proteome, Adenocarcinoma, Colonic Neoplasms, HSP90 Heat-Shock Proteins, Molecular Chaperones, Antineoplastic Agents, Mass Spectrometry, Chromatography, Gel

جغرافية الموضوع: United States

وصف الملف: Print-Electronic; application/pdf

العلاقة: 100485; S1535-9476(22)00293-6; Molecular and Cellular Proteomics, 2023, 22 (2), pp. 100485 -; https://repository.icr.ac.uk/handle/internal/5721Test

الإتاحة: https://doi.org/10.1016/j.mcpro.2022.100485Test
https://repository.icr.ac.uk/handle/internal/5721Test

المؤلفون: Kim, Jong Youl, Han, Yeonseung, Lee, Jong Eun, Yenari, Midori A

المصدر: Expert Opinion on Therapeutic Targets. 22(3)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Neurosciences, Brain Disorders, Stroke, Genetics, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, Aetiology, Animals, Brain Ischemia, Cell Death, Drug Design, HSP70 Heat-Shock Proteins, HSP90 Heat-Shock Proteins, Humans, Molecular Targeted Therapy, Neuroprotective Agents, Protein Folding, 70-kDa heat shock protein, chaperon, ischemic stroke, apoptosis, inflammation, neuroprotection, Artificial Intelligence and Image Processing, Oncology & Carcinogenesis, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3kk706kvTest

المؤلفون: Taylor, Isabelle R, Dunyak, Bryan M, Komiyama, Tomoko, Shao, Hao, Ran, Xu, Assimon, Victoria A, Kalyanaraman, Chakrapani, Rauch, Jennifer N, Jacobson, Matthew P, Zuiderweg, Erik RP, Gestwicki, Jason E

المصدر: Journal of Biological Chemistry. 293(11)

مصطلحات موضوعية: Biological Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Biotechnology, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Generic health relevance, Adaptor Proteins, Signal Transducing, Adenosine Triphosphatases, Apoptosis Regulatory Proteins, Binding Sites, Crystallography, X-Ray, Drug Discovery, Drug Evaluation, Preclinical, HSP40 Heat-Shock Proteins, HSP70 Heat-Shock Proteins, High-Throughput Screening Assays, Humans, Multiprotein Complexes, Pharmaceutical Preparations, Protein Binding, Protein Interaction Maps, Hsp70, heat shock protein, chemical biology, high-throughput screening, inhibition mechanism, inhibitor, molecular chaperone, protein complex, protein–protein interaction, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/23x9x9gnTest

المؤلفون: Cesa, Laura C, Shao, Hao, Srinivasan, Sharan R, Tse, Eric, Jain, Chetali, Zuiderweg, Erik RP, Southworth, Daniel R, Mapp, Anna K, Gestwicki, Jason E

المصدر: Journal of Biological Chemistry. 293(7)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Breast Cancer, Biotechnology, Generic health relevance, Biomarkers, Cell Line, Tumor, HSP70 Heat-Shock Proteins, HSP90 Heat-Shock Proteins, Humans, Protein Binding, Proto-Oncogene Mas, X-Linked Inhibitor of Apoptosis Protein, cancer biology, chaperone, chemical biology, heat shock protein 90, protein–protein interaction, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3fk7g6dvTest

المؤلفون: Rauch, Jennifer N, Zuiderweg, Erik RP, Gestwicki, Jason E

المصدر: Journal of Biological Chemistry. 291(38)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Underpinning research, Aetiology, Generic health relevance, Adaptor Proteins, Signal Transducing, Apoptosis Regulatory Proteins, DNA-Binding Proteins, HSC70 Heat-Shock Proteins, Humans, Multiprotein Complexes, Protein Binding, Protein Domains, Transcription Factors, kilodalton heat shock protein, molecular chaperone, nuclear magnetic resonance, protein complex, protein-protein interaction, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6sr0x68rTest

المؤلفون: Yim, Kendrick H, Prince, Thomas L, Qu, Shiwei, Bai, Fang, Jennings, Patricia A, Onuchic, José N, Theodorakis, Emmanuel A, Neckers, Leonard

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(33)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Computer Simulation, HEK293 Cells, HSP90 Heat-Shock Proteins, Humans, Mutagenesis, Site-Directed, Protein Domains, Protein Isoforms, Xanthones, molecular chaperone, heat-shock protein 90, isoform-specific inhibitor, molecular docking, caged xanthone

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6s88r49dTest