المؤلفون: Patel, Ashish, Gill, Dipender, Shungin, Dmitry, Mantzoros, Christos S, Knudsen, Lotte Bjerre, Bowden, Jack, Burgess, Stephen

مصطلحات موضوعية: GLP1R agonists, drug target Mendelian randomization, overdispersion heterogeneity, phenotypic heterogeneity, Humans, Mendelian Randomization Analysis, Glucagon-Like Peptide-1 Receptor, Diabetes Mellitus, Type 2, Coronary Artery Disease, Phenotype, Body Mass Index, Polymorphism, Single Nucleotide, Genetic Predisposition to Disease

الإتاحة: https://doi.org/10.17863/cam.106128Test
https://www.repository.cam.ac.uk/handle/1810/364436Test

المؤلفون: Harlow, C. E., Gandawijaya, J., Bamford, R. A., Martin, E. R., Wood, A. R., van der Most, P. J., Tanaka, T., Leonard, H. L., Etheridge, A. S., Innocenti, F., Beaumont, R. N., Tyrrell, J., Nalls, M. A., Simonsick, E. M., Garimella, P. S., Shiroma, E. J., Verweij, N., van der Meer, P., Gansevoort, R. T., Snieder, H., Gallins, P. J., Jima, D. D., Wright, F., Zhou, Y. H., Ferrucci, L., Bandinelli, S., Hernandez, D. G., van der Harst, P., Patel, V. V., Waterworth, D. M., Chu, A. Y., Oguro-Ando, A., Frayling, T. M.

مصطلحات موضوعية: Anemia/drug therapy/genetics, Coronary Artery Disease/genetics, Genome-Wide Association Study, Humans, Mendelian Randomization Analysis, Myocardial Infarction/genetics, Renal Insufficiency, Chronic/genetics, CRISPR-Cas9, anaemia in chronic kidney disease, cardiovascular disease risk, drug-target mendelian randomization, functional genomics, functional validation, gene editing, mendelian randomization, population studies, statistical genetics

العلاقة: https://linkinghub.elsevier.com/retrieve/pii/S0002-9297Test(22)00356-1; Am J Hum Genet. 2022 Sep 1;109(9):1638-1652. doi:10.1016/j.ajhg.2022.08.004.; https://rde.dspace-express.com/handle/11287/622619Test; American journal of human genetics

الإتاحة: https://doi.org/10.1016/j.ajhg.2022.08.004Test
https://rde.dspace-express.com/handle/11287/622619Test

المؤلفون: Charli E. Harlow, Josan Gandawijaya, Rosemary A. Bamford, Emily-Rose Martin, Andrew R. Wood, Peter J. van der Most, Toshiko Tanaka, Hampton L. Leonard, Amy S. Etheridge, Federico Innocenti, Robin N. Beaumont, Jessica Tyrrell, Mike A. Nalls, Eleanor M. Simonsick, Pranav S. Garimella, Eric J. Shiroma, Niek Verweij, Peter van der Meer, Ron T. Gansevoort, Harold Snieder, Paul J. Gallins, Dereje D. Jima, Fred Wright, Yi-hui Zhou, Luigi Ferrucci, Stefania Bandinelli, Dena G. Hernandez, Pim van der Harst, Vickas V. Patel, Dawn M. Waterworth, Audrey Y. Chu, Asami Oguro-Ando, Timothy M. Frayling

المساهمون: Cardiovascular Centre (CVC), Groningen Kidney Center (GKC), Life Course Epidemiology (LCE), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: American Journal of Human Genetics, 109(9), 1638-1652. CELL PRESS

مصطلحات موضوعية: anaemia in chronic kidney disease, genome-wide association study, gene editing, Myocardial Infarction, Anemia, population studies, Coronary Artery Disease, Mendelian Randomization Analysis, drug-target mendelian randomization, functional validation, cardiovascular disease risk, Genetics, Humans, mendelian randomization, statistical genetics, Renal Insufficiency, Chronic, CRISPR-Cas9, functional genomics, Genetics (clinical)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5af52c8198d180333920474519e29dTest
https://research.rug.nl/en/publications/dbc76815-e070-4ba9-801d-e653aebb2f58Test